Results 21 to 30 of about 4,943 (178)

Effect of Several Naja atra Antivenom Injection Methods on the Rabbit Model of Naja naja atra Bite Poisoning

Journal of Tropical Medicine, 2023
Snakebite is a global public health concern, which often occurs in tropical and subtropical underdeveloped areas, but it is often neglected. In the southern China, Naja naja atra (Chinese cobra) is a common venomous snake that causes swelling and ...
Jie Yang, Jin-Cheng Li, Zhou Huang, Dong-Ling Huang, Fan Wang, Wan-Xia Wei, Ji-Fei Nong, Feng Yang, Xue-Ling Lu, Jun-Rong Zhu, Wei Wang   +10 more
doaj   +1 more source

An Examination of the Neutralization of In Vitro Toxicity of Chinese Cobra (Naja atra) Venom by Different Antivenoms

Biomedicines, 2020
The Chinese Cobra (Naja atra) is an elapid snake of major medical importance in southern China. We describe the in vitro neurotoxic, myotoxic, and cytotoxic effects of N.
Qing Liang, Tam Minh Huynh, Nicki Konstantakopoulos, Geoffrey K. Isbister, Wayne C. Hodgson   +4 more
doaj   +1 more source

Current treatment for venom-induced consumption coagulopathy resulting from snakebite. [PDF]

PLoS Neglected Tropical Diseases, 2014
Venomous snakebite is considered the single most important cause of human injury from venomous animals worldwide. Coagulopathy is one of the commonest important systemic clinical syndromes and can be complicated by serious and life-threatening ...
Kalana Maduwage, Geoffrey K Isbister
doaj   +1 more source

Situation of snakebite, antivenom market and access to antivenoms in ASEAN countries

BMJ Global Health, 2022
Introduction Snakebite envenoming is a neglected tropical disease posing public health challenges globally. The Association of Southeast Asian Nations (ASEAN) countries are among the tropical regions with disproportionately high incidence of snakebite.
Chanthawat Patikorn, Ahmad Khaldun Ismail, Syafiq Asnawi Zainal Abidin, Francis Bonn Blanco, Jörg Blessmann, Khamla Choumlivong, John David Comandante, Uyen Vy Doan, Zainalabidin Mohamed @ Ismail, Yi Yi Khine, Tri Maharani, Myat Thet Nwe, Reza Murad Qamruddin, Ruth Sabrina Safferi, Emelia B Santamaria, Patrick Joseph G Tiglao, Satariya Trakulsrichai, Taksa Vasaruchapong, Nathorn Chaiyakunapruk, Suthira Taychakhoonavudh, Iekhsan Othman   +20 more
openaire   +3 more sources

Effectiveness of repeated antivenom therapy for snakebite-related systemic complications

Journal of International Medical Research, 2019
Objective This study aimed to determine the effect of repeated antivenom therapy compared with that of single antivenom therapy for treating snakebite-related systemic complications.
Kyung Hoon Park, Hyungoo Shin, Hyunggoo Kang, Changsun Kim, Hyuk Joong Choi, Kyunghun Yoo, Jaehoon Oh, Tae Ho Lim   +7 more
doaj   +1 more source

In-Vitro Neutralization of the Neurotoxicity of Coastal Taipan Venom by Australian Polyvalent Antivenom: The Window of Opportunity

Toxins, 2020
Coastal taipan (Oxyuranus scutellatus) envenoming causes life-threatening neuromuscular paralysis in humans. We studied the time period during which antivenom remains effective in preventing and arresting in vitro neuromuscular block caused by taipan ...
Umesha Madhushani, Geoffrey K. Isbister, Theo Tasoulis, Wayne C. Hodgson, Anjana Silva   +4 more
doaj   +1 more source

Antivenom supply and demand: An analysis of antivenom availability and utilization in South Africa

African Journal of Emergency Medicine, 2023
Snakebites are a neglected tropical disease. In many areas, envenoming incidence and antivenom administration rates are unknown. This study compared antivenom (AV) availability to rates of envenoming and recommendations to treat (RTT) in South Africa.This retrospective study identified, extracted, and reviewed all cases of envenoming (snake bites and ...
Natalie R Neumann, Arina du Plessis, Daniël J van Hoving, Christopher O Hoyte, Anné Lermer, Stephen Wittels, Carine Marks   +6 more
openaire   +3 more sources

Determination of potency and paraspecific effects of Androctonus crassicauda (Olivier, 1807) antivenom against Mesobuthus gibbosus (Brullé, 1832) venom (Scorpiones: Buthidae)

Journal of Venomous Animals and Toxins including Tropical Diseases, 2007
Scorpion envenomation remains a real health problem in many countries. In scorpionism cases, it is often recommended that patients be treated with species-specific antivenom. Androctonus crassicauda venom has been used as antigen for antivenom production
O. Ozkan, S. Adiguzel, S. Kar, S. Yakistiran, Y. Cesaretli, K. Z. Karaer   +5 more
doaj   +1 more source

Immunological profile of antivenoms: Preclinical analysis of the efficacy of a polyspecific antivenom through antivenomics and neutralization assays

Journal of Proteomics, 2014
Parenteral administration of animal-derived antivenoms constitutes the mainstay in the treatment of snakebite envenomings. Despite the fact that this therapy has been available for over a century, the detailed understanding of the neutralizing and immunoreactivity profiles of the majority of antivenoms is pending.
Gutiérrez, José María, Lomonte, Bruno, Sanz, Libia, Calvete Chornet, Juan José, Pla Ferrer, Davinia   +4 more
openaire   +4 more sources

Population Pharmacokinetics of an Indian F(ab')2 Snake Antivenom in Patients with Russell's Viper (Daboia russelii) Bites. [PDF]

PLoS Neglected Tropical Diseases, 2015
There is limited information on antivenom pharmacokinetics. This study aimed to investigate the pharmacokinetics of an Indian snake antivenom in humans with Russell's viper bites.Patient data and serial blood samples were collected from patients with ...
Geoffrey K Isbister, Kalana Maduwage, Ana Saiao, Nicholas A Buckley, Shaluka F Jayamanne, Shahmy Seyed, Fahim Mohamed, Umesh Chathuranga, Alexandre Mendes, Chandana Abeysinghe, Harindra Karunathilake, Indika Gawarammana, David G Lalloo, H Janaka de Silva   +13 more
doaj   +1 more source