Results 31 to 40 of about 4,943 (178)

A national survey examining recognition, demand for antivenom, and overall level of preparedness for redback spider bites in Japan

open access: yesAcute Medicine & Surgery, 2016
Aim Redback spiders are rapidly becoming a nationwide problem in Japan. The domestic production of antivenom for redback spider bites has been started because of extremely low supply.
Toru Hifumi   +11 more
doaj   +1 more source

Antivenoms for Snakebite Envenomings

open access: yesInflammation & Allergy - Drug Targets, 2011
Animal-derived antivenoms constitute the mainstay in the therapy of snakebite envenoming. Antivenoms are manufactured by immunizing animals, usually horses, with venoms from a single or several medically-relevant snake species. Antivenoms are constituted by either whole IgG molecules or the immunoglobulin fragments F(ab')₂ and Fab, obtained by ...
Gutiérrez, José María   +3 more
openaire   +4 more sources

Optimising the Eco‐Friendly Extraction of Carotenoids From Gac Fruit: A Sustainable Solution for Natural Red Food Colourants

open access: yesFood Chemistry International, EarlyView.
Gac fruit's high carotenoid content, especially in the aril, makes it an excellent natural red pigment source for food applications, offering a safer alternative to synthetic dyes. Ethanol extraction achieved the highest overall pigment recovery (89.53%), whereas ethyl lactate extraction yielded the highest levels of total carotenoids, β‐carotene ...
N. Netravati   +4 more
wiley   +1 more source

Artemia salina Toxicity Assay: Standardization in a 24‐Well Microplate

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Bioassays with Artemia sp. are widely used in aquatic, environmental, and human toxicology as an initial tool to investigate the toxicity of plant extracts, isolated compounds, drugs, and products of natural or synthetic origin. These assays allow for the estimation of the median lethal concentration (LC50) and guide subsequent studies in ...
Matheus Pires Miranda   +4 more
wiley   +1 more source

Identification of antigenic proteins from the venom of Malaysian snakes using immunoprecipitation assay and tandem mass spectrometry (LC-MS/MS)

open access: yesHeliyon
Snake envenomation poses a significant risk to Malaysians and country visitors. Malaysia witnesses an estimated 650 snake bites per 100,000 population annually.
Preetha Rajendiran   +3 more
doaj   +1 more source

Proteomics and immunocharacterization of Asian mountain pit viper (Ovophis monticola) venom.

open access: yesPLoS ONE, 2021
The venomic profile of Asian mountain pit viper Ovophis monticola is clarified in the present study. Using mass spectrometry-based proteomics, 247 different proteins were identified in crude venom of O. monticola found in Thailand.
Siravit Sitprija   +10 more
doaj   +1 more source

Reports of Doses Administered and Adverse Reactions to Snake Antivenom Used in Uruguay in 2018

open access: yesFrontiers in Toxicology, 2021
In Uruguay, around 60 cases of snakebite accidents occur every year that need to be treated with specific antivenom. They are caused by two snakes of Bothrops genus: Bothrops alternatus and Bothrops pubescens.
Alba Negrin   +3 more
doaj   +1 more source

Systemic impact of intramuscular snake envenomation and intravenous immunoglobulin‐based antivenom treatment on murine plasma proteome and peptidome

open access: yesProtein Science, Volume 35, Issue 9, September 2026.
Abstract Snake envenomation remains a critical global public health challenge. In Brazil, the genus Bothrops is responsible for most accidents, typically resulting in coagulopathy, hemorrhage, and renal failure. Despite its clinical prevalence, the molecular mechanisms driving plasma protein disturbances remain poorly understood.
Bianca C. S. C. de Barros   +6 more
wiley   +1 more source

A Novel Apilic Antivenom to Treat Massive, Africanized Honeybee Attacks: A Preclinical Study from the Lethality to Some Biochemical and Pharmacological Activities Neutralization

open access: yesToxins, 2021
Massive, Africanized honeybee attacks have increased in Brazil over the years. Humans and animals present local and systemic effects after envenomation, and there is no specific treatment for this potentially lethal event.
Jhonatha Mota Teixeira-Cruz   +9 more
doaj   +1 more source

Early Adverse Reactions to Snake Antivenom: Poison Center Data Analysis

open access: yesToxins, 2022
Antivenom is an essential treatment for snake envenomation; however, early adverse reactions (EARs) are major limitations to its use. We performed a retrospective cross-sectional study using Ramathibodi Poison Center data (January 2016 to December 2017 ...
Charuwan Sriapha   +5 more
doaj   +1 more source

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