Results 11 to 20 of about 9,545 (205)

Detection of Snake Venom in Post-Antivenom Samples by Dissociation Treatment Followed by Enzyme Immunoassay [PDF]

Toxins, 2016
Venom detection is crucial for confirmation of envenomation and snake type in snake-bite patients. Enzyme immunoassay (EIA) is used to detect venom, but antivenom in samples prevents venom detection.
Kalana P. Maduwage, Margaret A. O’Leary, Anjana Silva, Geoffrey K. Isbister   +3 more
doaj   +5 more sources

Polyspecific snake antivenom may help in antivenom crisis [PDF]

BMJ, 2003
EDITOR—In Africa snakebites cause thousands of deaths annually and much permanent physical disability, but the supply of antivenom, the only specific treatment, is threatened by commercial pressures and privatisation. This has been caused over the past few years by the cessation of antivenom manufacture by Behringwerke in Germany, greatly reduced ...
Laing, G, Harrison, R, Theakston, R, Renjifo, J, Nasidi, A, Gutierrez, J, Warrell, D   +6 more
openaire   +6 more sources

Hemoperfusion as Adjunctive Therapy in Severe Snake Envenomation Refractory to Antivenom: A Case Series. [PDF]

Clin Case Rep
ABSTRACT Snake envenomation remains a significant cause of morbidity worldwide, with antivenom serving as the cornerstone of treatment. This case series describes outcomes of three male patients (ages 34–63 years) with severe envenomation who demonstrated progressive local swelling and coagulopathy despite receiving at least 15 vials of antivenom.
Hosseini SM, Shadnia S, Mostafazadeh B, Rahimi M, Zandiyeh F, Nezhad AR, Evini PET.   +6 more
europepmc   +2 more sources

Systemic impact of intramuscular snake envenomation and intravenous immunoglobulin-based antivenom treatment on murine plasma proteome and peptidome. [PDF]

Protein Sci
Abstract Snake envenomation remains a critical global public health challenge. In Brazil, the genus Bothrops is responsible for most accidents, typically resulting in coagulopathy, hemorrhage, and renal failure. Despite its clinical prevalence, the molecular mechanisms driving plasma protein disturbances remain poorly understood.
de Barros BCSC, Chaves AFA, Morone MSLC, Sachetto ATA, Santoro ML, Schilling O, Serrano SMT.   +6 more
europepmc   +2 more sources

Venoms, venomics, antivenomics [PDF]

FEBS Letters, 2009
Venoms comprise mixtures of peptides and proteins tailored by Natural Selection to act on vital systems of the prey or victim. Here we review our proteomic protocols for uncoiling the composition, immunological profile, and evolution of snake venoms. Our long‐term goal is to gain a deep insight of all viperid venom proteomes.
Calvete Chornet, Juan José, Sanz, Libia, Angulo Ugalde, Yamileth, Lomonte, Bruno, Gutiérrez, José María   +4 more
openaire   +4 more sources

Cytotoxic Effect of Bee (A. mellifera) Venom on Cancer Cell Lines

Journal of Pharmacopuncture, 2020
Objectives: Nowadays cancer treatment is an important challenge in the medical world that needs better therapies. Many active secretions produced by insects such as honey bees used to discover new anticancer drugs.
Sima Khalilifard Borojeni, Hossein Zolfagharian, Mahdi Babaie, Iraj Javadi   +3 more
doaj   +1 more source

Availability of antivenom, and antivenom and adrenaline, per level and sector.

, 2021
Availability of antivenom, and antivenom and adrenaline, per level and sector.
Aukje K Mantel-Teeuwisse (8179767), Eugene Erulu (11278987), Janneke van Oirschot (11278978), Benjamin Waldmann (11278984), Hendrika A van den Ham (11278990), Dorothy Okemo (11278981), Tim Reed (9084869), Gaby Isabelle Ooms (11278975)   +7 more
core   +1 more source

Drug Discovery for Snakebite Envenoming: Wanderings Amid Historical Antidotes and Emerging Therapeutic Opportunities. [PDF]

ChemMedChem
In this review, we provide an overview of selected historical antidotes against snakebite envenomation used in early modern Europe. Then, the evidence‐based antivenom activity of some natural compounds is discussed as resulting from more than two decades of research studies.
Bianconi E, Camaioni E, Oszajca P, Macchiarulo A.   +3 more
europepmc   +2 more sources

PHASE II UNCONTROLLED OPEN-LABEL CLINICAL TRIAL, DETECTING SAFETY, AND NON-SPECIFIC THERAPEUTIC BENEFITS OF BEE VENOM PRODUCT ABEVAC [PDF]

Journal of the Egyptian Society of Parasitology
Generally speaking, the bee venom is widely used as a natural treatment for many diseases. In orderto ascertain the safety and the therapeutic effect of a bee venom formulation, 500 male and femalepatients with complex disease cases were given ...
ABIR EL-FIKY, SHERIF ELFEEL, MOSTAFA MOHAMADY, MOHAMMED ELMARAKBY, SHYMAA YEHIA, TOSSON MORSY, DINA AFIFI, NOHA SHAHEEN, EMAN HAMMODA, DOAA ABD ELFATTAH   +9 more
doaj   +1 more source

CROSS NEUTRALIZATION OF SOME KINDS OF VIPERS AND SNAKE VENOMS FROM AFRICA AND MIDDLE EAST USING VACSERA POLYVALENT VIPER ANTISERA [PDF]

Journal of the Egyptian Society of Parasitology, 2022
As the death rate due to snake bites was differ enormously between different countries, thestudy conducted was an extensive of neutralization of lethality of two species of genus Naja,seven species of genus Vipera, and two species of Macrovipera by using
YASMIN MOHAMED, MOHAMED ZID, ERENE GIRGIS, ABIR ELFIKY   +3 more
doaj   +1 more source