Results 11 to 20 of about 4,943 (178)

Diagnosing Syndrome-Like Microangiopathic Hemolytic Anemia After Pit Viper Envenomation: Overcoming Laboratory Gaps in a Resource-Limited Setting: A Case Report From Nepal. [PDF]

Clin Case Rep
ABSTRACT Snakebite envenomation remains a significant yet often overlooked health challenge in Nepal, particularly in its rural and hilly regions. While venom‐induced consumption coagulopathy (VICC) is commonly observed with viper bites, microangiopathic hemolytic anemia (MAHA) is an extremely rare complication, especially with green pit vipers ...
Kaphle P, Gupta P, Shrestha S, Diyali N, Koirala RK, Shrestha A, Giri D, Pahari N, Sah AK, Hamal K, Bohara S.   +10 more
europepmc   +2 more sources

Severe Pediatric Snakebite With Coagulopathy and Compartment Syndrome: Conservative Management With Plasma Exchange. [PDF]

Clin Case Rep
Therapeutic plasma exchange was successfully used in a child with severe snakebite envenomation complicated by refractory venom‐induced consumptive coagulopathy and suspected compartment syndrome, leading to full recovery and avoidance of surgical intervention.
Al Muqbel ZM, Al-Majmuei A, Haider Ali A, Fahad NY, Ajjawi R, Al Dailami A, Lone A, Al Maskati M, Mohamed Mansoor N.   +8 more
europepmc   +2 more sources

Venoms, venomics, antivenomics [PDF]

FEBS Letters, 2009
Venoms comprise mixtures of peptides and proteins tailored by Natural Selection to act on vital systems of the prey or victim. Here we review our proteomic protocols for uncoiling the composition, immunological profile, and evolution of snake venoms. Our long‐term goal is to gain a deep insight of all viperid venom proteomes.
Calvete Chornet, Juan José, Sanz, Libia, Angulo Ugalde, Yamileth, Lomonte, Bruno, Gutiérrez, José María   +4 more
openaire   +4 more sources

PHASE II UNCONTROLLED OPEN-LABEL CLINICAL TRIAL, DETECTING SAFETY, AND NON-SPECIFIC THERAPEUTIC BENEFITS OF BEE VENOM PRODUCT ABEVAC [PDF]

Journal of the Egyptian Society of Parasitology
Generally speaking, the bee venom is widely used as a natural treatment for many diseases. In orderto ascertain the safety and the therapeutic effect of a bee venom formulation, 500 male and femalepatients with complex disease cases were given ...
ABIR EL-FIKY, SHERIF ELFEEL, MOSTAFA MOHAMADY, MOHAMMED ELMARAKBY, SHYMAA YEHIA, TOSSON MORSY, DINA AFIFI, NOHA SHAHEEN, EMAN HAMMODA, DOAA ABD ELFATTAH   +9 more
doaj   +1 more source

Experimental Bothrops atrox envenomation: Efficacy of antivenom therapy and the combination of Bothrops antivenom with dexamethasone. [PDF]

PLoS Neglected Tropical Diseases, 2017
Bothrops atrox snakes are the leading cause of snake bites in Northern Brazil. The venom of this snake is not included in the antigen pool used to obtain the Bothrops antivenom. There are discrepancies in reports on the effectiveness of this antivenom to
Gabriella Neves Leal Santos Barreto, Sâmella Silva de Oliveira, Isabelle Valle Dos Anjos, Hipocrates de Menezes Chalkidis, Rosa Helena Veras Mourão, Ana Maria Moura-da-Silva, Ida Sigueko Sano-Martins, Luis Roberto de Camargo Gonçalves   +7 more
doaj   +1 more source

Polyspecific snake antivenom may help in antivenom crisis [PDF]

BMJ, 2003
EDITOR—In Africa snakebites cause thousands of deaths annually and much permanent physical disability, but the supply of antivenom, the only specific treatment, is threatened by commercial pressures and privatisation. This has been caused over the past few years by the cessation of antivenom manufacture by Behringwerke in Germany, greatly reduced ...
Laing, G, Harrison, R, Theakston, R, Renjifo, J, Nasidi, A, Gutierrez, J, Warrell, D   +6 more
openaire   +4 more sources

Cytotoxic Effect of Bee (A. mellifera) Venom on Cancer Cell Lines

Journal of Pharmacopuncture, 2020
Objectives: Nowadays cancer treatment is an important challenge in the medical world that needs better therapies. Many active secretions produced by insects such as honey bees used to discover new anticancer drugs.
Sima Khalilifard Borojeni, Hossein Zolfagharian, Mahdi Babaie, Iraj Javadi   +3 more
doaj   +1 more source

Detection of Snake Venom in Post-Antivenom Samples by Dissociation Treatment Followed by Enzyme Immunoassay

Toxins, 2016
Venom detection is crucial for confirmation of envenomation and snake type in snake-bite patients. Enzyme immunoassay (EIA) is used to detect venom, but antivenom in samples prevents venom detection.
Kalana P. Maduwage, Margaret A. O’Leary, Anjana Silva, Geoffrey K. Isbister   +3 more
doaj   +1 more source

Pharmacodynamics and pharmacokinetics of snake antivenom

Sri Lanka Journal of Medicine, 2018
Intact or fractionated immunoglobulins are used as snake antivenom to treat snake envenomation. Intravenously administered antivenom binds with snake toxins in the circulation and neutralizes the toxins.
Bhagya Nikapitiya, Kalana Maduwage
doaj   +1 more source

Consequences of neglect: analysis of the sub-Saharan African snake antivenom market and the global context. [PDF]

PLoS Neglected Tropical Diseases, 2012
BACKGROUND: The worldwide neglect of immunotherapeutic products for the treatment of snakebite has resulted in a critical paucity of effective, safe and affordable therapy in many Third World countries, particularly in Africa.
Nicholas I Brown
doaj   +1 more source