Snake Venomics and Antivenomics of Bothrops diporus, a Medically Important Pitviper in Northeastern Argentina [PDF]
, 2015 Snake species within genus Bothrops are responsible for more than 80% of the snakebites occurring in South America. The species that cause most envenomings in Argentina, B.
Calvete, Juan J. +3 more
core +9 more sources
Evaluating Antivenom Efficacy against Echis carinatus Venoms—Screening for In Vitro Alternatives
Toxins, 2022 In India, polyvalent antivenom is the mainstay treatment for snakebite envenoming. Due to batch-to-batch variation in antivenom production, manufacturers have to estimate its efficacy at each stage of IgG purification using the median effective dose ...
Siddharth Bhatia +2 more
doaj +1 more source
Cytotoxic Effect of Bee (A. mellifera) Venom on Cancer Cell Lines
Journal of Pharmacopuncture, 2020 Objectives: Nowadays cancer treatment is an important challenge in the medical world that needs better therapies. Many active secretions produced by insects such as honey bees used to discover new anticancer drugs.
Sima Khalilifard Borojeni +3 more
doaj +1 more source
Polyspecific snake antivenom may help in antivenom crisis [PDF]
BMJ, 2003 EDITOR—In Africa snakebites cause thousands of deaths annually and much permanent physical disability, but the supply of antivenom, the only specific treatment, is threatened by commercial pressures and privatisation. This has been caused over the past few years by the cessation of antivenom manufacture by Behringwerke in Germany, greatly reduced ...
Laing, G +6 more
openaire +4 more sources
Repurposing cancer drugs, batimastat and marimastat, to inhibit the activity of a group I metalloprotease from the venom of the Western Diamondback rattlesnake, Crotalus atrox [PDF]
, 2020 Snakebite envenomation causes over 140,000 deaths every year predominantly in developing countries. As a result, it is one of the most lethal neglected tropical diseases.
Bicknell, Andrew B. +12 more
core +1 more source
PHASE II UNCONTROLLED OPEN-LABEL CLINICAL TRIAL, DETECTING SAFETY, AND NON-SPECIFIC THERAPEUTIC BENEFITS OF BEE VENOM PRODUCT ABEVAC [PDF]
Journal of the Egyptian Society of ParasitologyGenerally speaking, the bee venom is widely used as a natural treatment for many diseases. In orderto ascertain the safety and the therapeutic effect of a bee venom formulation, 500 male and femalepatients with complex disease cases were given ...
ABIR EL-FIKY +9 more
doaj +1 more source
Snakebite: An Exploratory Cost-Effectiveness Analysis of Adjunct Treatment Strategies. [PDF]
, 2018 The cost-effectiveness of the standard of care for snakebite treatment, antivenom, and supportive care has been established in various settings. In this study, based on data from South Indian private health-care providers, we address an additional ...
Bulfone, Tommaso C +5 more
core +2 more sources
Experimental Bothrops atrox envenomation: Efficacy of antivenom therapy and the combination of Bothrops antivenom with dexamethasone. [PDF]
PLoS Neglected Tropical Diseases, 2017 Bothrops atrox snakes are the leading cause of snake bites in Northern Brazil. The venom of this snake is not included in the antigen pool used to obtain the Bothrops antivenom. There are discrepancies in reports on the effectiveness of this antivenom to
Gabriella Neves Leal Santos Barreto +7 more
doaj +1 more source
Toxins, 2016 Venom detection is crucial for confirmation of envenomation and snake type in snake-bite patients. Enzyme immunoassay (EIA) is used to detect venom, but antivenom in samples prevents venom detection.
Kalana P. Maduwage +3 more
doaj +1 more source
Pharmacodynamics and pharmacokinetics of snake antivenom
Sri Lanka Journal of Medicine, 2018 Intact or fractionated immunoglobulins are used as snake antivenom to treat snake envenomation. Intravenously administered antivenom binds with snake toxins in the circulation and neutralizes the toxins.
Bhagya Nikapitiya, Kalana Maduwage
doaj +1 more source