Results 11 to 20 of about 18,419 (261)

In Vitro Efficacy of Antivenom and Varespladib in Neutralising Chinese Russell’s Viper (Daboia siamensis) Venom Toxicity

Toxins, 2023
The venom of the Russell’s viper (Daboia siamensis) contains neurotoxic and myotoxic phospholipase A2 toxins which can cause irreversible damage to motor nerve terminals.
Mimi Lay, Qing Liang, G. Isbister, W. Hodgson   +3 more
semanticscholar   +1 more source

The Need for Next-Generation Antivenom for Snakebite Envenomation in India

Toxins, 2023
The limitations posed by currently available antivenoms have emphasized the need for alternative treatments to counteract snakebite envenomation. Even though exact epidemiological data are lacking, reports have indicated that most global snakebite deaths
Muralidharan Vanuopadath, Karthika Rajan, Aswathy Alangode, Sudarslal Sadasivan Nair, B. Nair   +4 more
semanticscholar   +1 more source

First Case Report of an Unusual Echis genus (Squamata: Ophidia: Viperidae) Body Pattern Design in Iran [PDF]

Archives of Razi Institute, 2019
Three families of venomous snakes exist in Iran including Viperidae, Elapidae, and Hydrophidae. Viperidae family is the only family with a widespread distribution. Saw-scaled vipers are important poisonous snakes in Asia and Africa. This name is given to
S. Navidpour, A. Salemi, A. Zare Mirakabadi   +2 more
doaj   +1 more source

Antivenom preclinical efficacy testing against Asian snakes and their availability in Asia: A systematic review

PLoS ONE, 2023
Background Cross-neutralizing strategy has been applied to improve access to antivenoms, a key to reducing mortality and disability of snakebite envenoming.
Sutinee Soopairin, C. Patikorn, S. Taychakhoonavudh   +2 more
semanticscholar   +1 more source

Situation of snakebite, antivenom market and access to antivenoms in ASEAN countries

BMJ Global Health, 2022
Introduction Snakebite envenoming is a neglected tropical disease posing public health challenges globally. The Association of Southeast Asian Nations (ASEAN) countries are among the tropical regions with disproportionately high incidence of snakebite ...
C. Patikorn, A. Ismail, S. Z. Abidin, Francis Bonn Blanco, J. Blessmann, Khamla Choumlivong, J. D. Comandante, U. V. Doan, Yi Yi Khine, Tri Maharani, M. Nwe, R. Qamruddin, Ruth Sabrina Safferi, Emelia B. Santamaria, P. Tiglao, S. Trakulsrichai, T. Vasaruchapong, N. Chaiyakunapruk, S. Taychakhoonavudh, Iekhsan Othman   +19 more
semanticscholar   +1 more source

Plant-Derived Toxin Inhibitors as Potential Candidates to Complement Antivenom Treatment in Snakebite Envenomations

Frontiers in Immunology, 2022
Snakebite envenomations (SBEs) are a neglected medical condition of global importance that mainly affect the tropical and subtropical regions. Clinical manifestations include pain, edema, hemorrhage, tissue necrosis, and neurotoxic signs, and may evolve ...
A. Adrião, Aline O. dos Santos, Emilly J. S. P. de Lima, J. B. Maciel, Weider H. P. Paz, F. D. da Silva, Manuela B Pucca, A. Moura-da-Silva, W. Monteiro, M. Sartim, H. Koolen   +10 more
semanticscholar   +1 more source

A Review of the Proteomic Profiling of African Viperidae and Elapidae Snake Venoms and Their Antivenom Neutralisation

Toxins, 2022
Snakebite envenoming is a neglected tropical disease (NTD) that results from the injection of snake venom of a venomous snake into animals and humans.
Benedict C Offor, Beric Muller, L. Piater   +2 more
semanticscholar   +1 more source

Snake Venomics and Antivenomics of Bothrops diporus, a Medically Important Pitviper in Northeastern Argentina [PDF]

, 2015
Snake species within genus Bothrops are responsible for more than 80% of the snakebites occurring in South America. The species that cause most envenomings in Argentina, B.
Calvete, Juan J., Gay, Claudia Carolina, Pla, Davinia, Sanz, Libia   +3 more
core   +6 more sources

Cytotoxic Effect of Bee (A. mellifera) Venom on Cancer Cell Lines

Journal of Pharmacopuncture, 2020
Objectives: Nowadays cancer treatment is an important challenge in the medical world that needs better therapies. Many active secretions produced by insects such as honey bees used to discover new anticancer drugs.
Sima Khalilifard Borojeni, Hossein Zolfagharian, Mahdi Babaie, Iraj Javadi   +3 more
doaj   +1 more source

Repurposing cancer drugs, batimastat and marimastat, to inhibit the activity of a group I metalloprotease from the venom of the Western Diamondback rattlesnake, Crotalus atrox [PDF]

, 2020
Snakebite envenomation causes over 140,000 deaths every year predominantly in developing countries. As a result, it is one of the most lethal neglected tropical diseases.
Bicknell, Andrew B., Lakshminarayanan, Karthik, Layfield, Harry J., Mehmi, Amita, Patel, Ketan, Ravishankar, Divyashree, Salim, Anika, Sonavane, Medha, Trim, Steven A., Vaiyapuri, Rajendran, Vaiyapuri, Sakthivel, Vallance, Thomas M., Williams, Harry F.   +12 more
core   +1 more source