Results 41 to 50 of about 9,108 (207)

An Examination of the Neutralization of In Vitro Toxicity of Chinese Cobra (Naja atra) Venom by Different Antivenoms

Biomedicines, 2020
The Chinese Cobra (Naja atra) is an elapid snake of major medical importance in southern China. We describe the in vitro neurotoxic, myotoxic, and cytotoxic effects of N.
Qing Liang, Tam Minh Huynh, Nicki Konstantakopoulos, Geoffrey K. Isbister, Wayne C. Hodgson   +4 more
doaj   +1 more source

Effect of Several Naja atra Antivenom Injection Methods on the Rabbit Model of Naja naja atra Bite Poisoning

Journal of Tropical Medicine, 2023
Snakebite is a global public health concern, which often occurs in tropical and subtropical underdeveloped areas, but it is often neglected. In the southern China, Naja naja atra (Chinese cobra) is a common venomous snake that causes swelling and ...
Jie Yang, Jin-Cheng Li, Zhou Huang, Dong-Ling Huang, Fan Wang, Wan-Xia Wei, Ji-Fei Nong, Feng Yang, Xue-Ling Lu, Jun-Rong Zhu, Wei Wang   +10 more
doaj   +1 more source

Consequences of neglect: analysis of the sub-Saharan African snake antivenom market and the global context. [PDF]

PLoS Neglected Tropical Diseases, 2012
BACKGROUND: The worldwide neglect of immunotherapeutic products for the treatment of snakebite has resulted in a critical paucity of effective, safe and affordable therapy in many Third World countries, particularly in Africa.
Nicholas I Brown
doaj   +1 more source

Situation of snakebite, antivenom market and access to antivenoms in ASEAN countries

BMJ Global Health, 2022
Introduction Snakebite envenoming is a neglected tropical disease posing public health challenges globally. The Association of Southeast Asian Nations (ASEAN) countries are among the tropical regions with disproportionately high incidence of snakebite.
Chanthawat Patikorn, Ahmad Khaldun Ismail, Syafiq Asnawi Zainal Abidin, Francis Bonn Blanco, Jörg Blessmann, Khamla Choumlivong, John David Comandante, Uyen Vy Doan, Zainalabidin Mohamed @ Ismail, Yi Yi Khine, Tri Maharani, Myat Thet Nwe, Reza Murad Qamruddin, Ruth Sabrina Safferi, Emelia B Santamaria, Patrick Joseph G Tiglao, Satariya Trakulsrichai, Taksa Vasaruchapong, Nathorn Chaiyakunapruk, Suthira Taychakhoonavudh, Iekhsan Othman   +20 more
openaire   +3 more sources

In-Vitro Neutralization of the Neurotoxicity of Coastal Taipan Venom by Australian Polyvalent Antivenom: The Window of Opportunity

Toxins, 2020
Coastal taipan (Oxyuranus scutellatus) envenoming causes life-threatening neuromuscular paralysis in humans. We studied the time period during which antivenom remains effective in preventing and arresting in vitro neuromuscular block caused by taipan ...
Umesha Madhushani, Geoffrey K. Isbister, Theo Tasoulis, Wayne C. Hodgson, Anjana Silva   +4 more
doaj   +1 more source

Effectiveness of repeated antivenom therapy for snakebite-related systemic complications

Journal of International Medical Research, 2019
Objective This study aimed to determine the effect of repeated antivenom therapy compared with that of single antivenom therapy for treating snakebite-related systemic complications.
Kyung Hoon Park, Hyungoo Shin, Hyunggoo Kang, Changsun Kim, Hyuk Joong Choi, Kyunghun Yoo, Jaehoon Oh, Tae Ho Lim   +7 more
doaj   +1 more source

Accessibility of antivenom, per sector.

, 2021
Accessibility of antivenom, per sector.
Aukje K Mantel-Teeuwisse (8179767), Eugene Erulu (11278987), Janneke van Oirschot (11278978), Benjamin Waldmann (11278984), Hendrika A van den Ham (11278990), Dorothy Okemo (11278981), Tim Reed (9084869), Gaby Isabelle Ooms (11278975)   +7 more
core   +1 more source

Immunological profile of antivenoms: Preclinical analysis of the efficacy of a polyspecific antivenom through antivenomics and neutralization assays

Journal of Proteomics, 2014
Parenteral administration of animal-derived antivenoms constitutes the mainstay in the treatment of snakebite envenomings. Despite the fact that this therapy has been available for over a century, the detailed understanding of the neutralizing and immunoreactivity profiles of the majority of antivenoms is pending.
Gutiérrez, José María, Lomonte, Bruno, Sanz, Libia, Calvete Chornet, Juan José, Pla Ferrer, Davinia   +4 more
openaire   +4 more sources

Odds of myotoxicity following red-bellied black snake envenomation in patients that received early antivenom and late/no antivenom treatment.

, 2021
Odds of myotoxicity following red-bellied black snake envenomation in patients that received early antivenom and late/no antivenom treatment.
Geoffrey K. Isbister (8281572), Suchaya Sanhajariya (4810434), Stephen B. Duffull (10577008)   +2 more
core   +1 more source

Determination of potency and paraspecific effects of Androctonus crassicauda (Olivier, 1807) antivenom against Mesobuthus gibbosus (Brullé, 1832) venom (Scorpiones: Buthidae)

Journal of Venomous Animals and Toxins including Tropical Diseases, 2007
Scorpion envenomation remains a real health problem in many countries. In scorpionism cases, it is often recommended that patients be treated with species-specific antivenom. Androctonus crassicauda venom has been used as antigen for antivenom production
O. Ozkan, S. Adiguzel, S. Kar, S. Yakistiran, Y. Cesaretli, K. Z. Karaer   +5 more
doaj   +1 more source