Results 1 to 10 of about 10,435 (209)

Snakebite epidemiology, outcomes and multi-cluster risk modelling in Eswatini [PDF]

PLoS Neglected Tropical Diseases, 2023
BackgroundHalving snakebite morbidity and mortality by 2030 requires countries to develop both prevention and treatment strategies. The paucity of data on the global incidence and severity of snakebite envenoming causes challenges in prioritizing and ...
Sara Padidar
exaly   +5 more sources

Snakebite in Indonesia [PDF]

Acta Medica Indonesiana, 2016
Indonesia as one of the largest tropical and agricultural countries in the world shared the particularly high burden cases of snakebite. In the last decade, World Health Organization (WHO) has listed snakebite as one of the neglected tropical disease ...
Randy Adiwinata, Erni J Nelwan
doaj   +8 more sources

Knowledge of health workers on snakes and snakebite management and treatment seeking behavior of snakebite victims in Bhutan

PLoS Neglected Tropical Diseases, 2020
BackgroundPublished information on snakebite is rare in Bhutan although remarkably higher number of snakebites and associated deaths are reported from other South Asian countries.Aims and methodologyStructured questionnaire was used to collect knowledge ...
Sunil Sapkota, Dhan Bdr Gurung, Guru Dhakal   +2 more
exaly   +3 more sources

Repurposed small molecule toxin inhibitors neutralise a diversity of venoms from the Neotropical viperid snake genus Bothrops [PDF]

eLife
Snakebite globally claims more than 100,000 lives per year and results in morbidity for 400,000 survivors. Current treatment uses antibody-based antivenoms which are constrained by their efficacy, safety, and cost. In this study we evaluated the efficacy
Rachel H Clare, Adam Westhorpe, Emma Stars, Taline D Kazandjian, Laura-Oana Albulescu, Stefanie K Menzies, Nicholas R Casewell   +6 more
doaj   +2 more sources

Estimating snakebite incidence from mathematical models: A test in Costa Rica

PLoS Neglected Tropical Diseases, 2019
BackgroundSnakebite envenoming is a neglected public health challenge that affects mostly economically deprived communities who inhabit tropical regions.
Juan Cordovez, CARLOS Andres Bravo-Vega, Mauricio Santos Vega   +2 more
exaly   +2 more sources

Namibian spitting cobra, Naja nigricincta nigricincta (Zebra snake): Antibiotic profile of bacteria cultured from the oral pharynx, venom and snakebite wounds

South African Medical Journal, 2023
This was a cross-sectional study with the aim of characterising Naja nigricincta nigricincta’s oral bacterial flora as well as accompanying sensitivities and resistance towards antibiotics.
E Saaiman, C Buys, F Theart
doaj   +1 more source

Virus-like particles displaying conserved toxin epitopes stimulate polyspecific, murine antibody responses capable of snake venom recognition

Scientific Reports, 2022
Antivenom is currently the first-choice treatment for snakebite envenoming. However, only a low proportion of antivenom immunoglobulins are specific to venom toxins, resulting in poor dose efficacy and potency.
Stefanie K. Menzies, Charlotte A. Dawson, Edouard Crittenden, Rebecca J. Edge, Steven R. Hall, Jaffer Alsolaiss, Mark C. Wilkinson, Nicholas R. Casewell, Robert A. Harrison, Stuart Ainsworth   +9 more
doaj   +1 more source

Fatal infective necrotising fasciitis: Complication following Naja nigricincta nigricincta bite (western barred spitting cobra/zebra snake)

South African Medical Journal, 2022
Wound infections following cytotoxic snakebites are common. Bites from Naja nigricincta nigricincta (an African spitting cobra) usually present as severe dermonecrosis spreading within the subdermal fascia layer.
EL Saaiman, PJ (Christo) Buys
doaj   +1 more source

Exploring the Utility of Recombinant Snake Venom Serine Protease Toxins as Immunogens for Generating Experimental Snakebite Antivenoms

Toxins, 2022
Snakebite is a neglected tropical disease that causes high rates of global mortality and morbidity. Although snakebite can cause a variety of pathologies in victims, haemotoxic effects are particularly common and are typically characterised by ...
Nessrin Alomran, Patricia Blundell, Jaffer Alsolaiss, Edouard Crittenden, Stuart Ainsworth, Charlotte A. Dawson, Rebecca J. Edge, Steven R. Hall, Robert A. Harrison, Mark C. Wilkinson, Stefanie K. Menzies, Nicholas R. Casewell   +11 more
doaj   +1 more source

Delays, fears and training needs: Perspectives of health workers on clinical management of snakebite revealed by a qualitative study in Kitui County, Kenya

Toxicon: X, 2021
Key aims of the WHO Strategy to halve snakebite morbidity and mortality include health system strengthening and training of health workers. This requires knowledge of local health system needs and capacity, health worker training needs, and factors ...
Kieran Barnes, Cecelia Ngari, Stanley Parkurito, Leo Wood, Denis Otundo, Robert Harrison, George O. Oluoch, Anna Trelfa, Clare Baker   +8 more
doaj   +1 more source