Results 1 to 10 of about 3,616 (129)

A polyvalent coral snake antivenom with broad neutralization capacity. [PDF]

PLoS Neglected Tropical Diseases, 2019
Coral snakes of the genus Micrurus have a high diversity and wide distribution in the Americas. Despite envenomings by these animals being uncommon, accidents are often severe and may result in death. Producing an antivenom to treat these envenomings has
María Carlina Castillo-Beltrán, Juan Pablo Hurtado-Gómez, Vladimir Corredor-Espinel, Francisco Javier Ruiz-Gómez   +3 more
doaj   +2 more sources

Mass Spectrometry-Based Quantification in Snake Venomics and Antivenomics: Current Trends and Future Perspectives [PDF]

Life
Snake venomics and antivenomics approaches have increasingly relied on mass spectrometry to characterize the venom components and to evaluate the antivenom neutralization potential.
Nisha Reghu, Bipin Gopalakrishnan Nair, Muralidharan Vanuopadath   +2 more
doaj   +2 more sources

Pharmacodynamics and Pharmacokinetics of Snake Antivenom

Sri Lanka Journal of Medicine, 2018
Intact or fractionated immunoglobulins are used as snake antivenom to treat snake envenomation. Intravenously administered antivenom binds with snake toxins in the circulation and neutralizes the toxins.
Kalana Maduwage
exaly   +3 more sources

Antivenom Cross-Neutralization of the Venoms of Hydrophis Schistosus and Hydrophis curtus, Two Common Sea Snakes in Malaysian Waters

Toxins, 2015
Sea snake envenomation is a serious occupational hazard in tropical waters. In Malaysia, the beaked sea snake (Hydrophis schistosus, formerly known as Enhydrina schistosa) and the spine-bellied sea snake (Hydrophis curtus, formerly known as Lapemis ...
Kae Yi Tan, Choo Hock Tan, Nget Hong Tan
exaly   +3 more sources

A Review of the Proteomic Profiling of African Viperidae and Elapidae Snake Venoms and Their Antivenom Neutralisation

Toxins, 2022
Snakebite envenoming is a neglected tropical disease (NTD) that results from the injection of snake venom of a venomous snake into animals and humans.
Benedict C Offor, Lizelle A Piater
exaly   +3 more sources

The Snake Study: Survey of National Attitudes and Knowledge in Envenomation

Toxins, 2021
Despite recent reviews of best practice for the treatment of Australian venomous bites and stings, there is controversy about some aspects of care, particularly the use of antivenom.
George Braitberg, Vasilios Nimorakiotakis, Celene Y.L. Yap, Violet Mukaro, Ronelle Welton, Anna Parker, Jonathan Knott, David Story   +7 more
doaj   +1 more source

Proteomic Analysis, Immuno-Specificity and Neutralization Efficacy of Pakistani Viper Antivenom (PVAV), a Bivalent Anti-Viperid Antivenom Produced in Pakistan

Toxins, 2023
Snakebite envenoming is a neglected tropical disease prevalent in South Asia. In Pakistan, antivenoms are commonly imported from India despite the controversy over their effectiveness.
Andy Shing Seng Lim, Kae Yi Tan, Naeem H. Quraishi, Saud Farooque, Zahoor Ahmed Khoso, Kavi Ratanabanangkoon, Choo Hock Tan   +6 more
doaj   +1 more source

Focused Proteomics Analysis of Habu Snake (Protobothrops flavoviridis) Venom Using Antivenom-Based Affinity Chromatography Reveals Novel Myonecrosis-Enhancing Activity of Thrombin-Like Serine Proteases

Frontiers in Pharmacology, 2021
Snakebites are one of the major causes of death and long-term disability in the developing countries due to the presence of various bioactive peptides and proteins in snake venom.
Tomohisa Ogawa, Tomohisa Ogawa, Yu Tobishima, Shizuka Kamata, Youhei Matsuda, Koji Muramoto, Masafumi Hidaka, Eugene Futai, Takeshi Kuraishi, Shinichi Yokota, Motonori Ohno, Shosaku Hattori   +11 more
doaj   +1 more source

Clinical effects and antivenom dosing in brown snake (Pseudonaja spp.) envenoming--Australian snakebite project (ASP-14). [PDF]

PLoS ONE, 2012
BACKGROUND: Snakebite is a global health issue and treatment with antivenom continues to be problematic. Brown snakes (genus Pseudonaja) are the most medically important group of Australian snakes and there is controversy over the dose of brown snake ...
George E Allen, Simon G A Brown, Nicholas A Buckley, Margaret A O'Leary, Colin B Page, Bart J Currie, Julian White, Geoffrey K Isbister, ASP Investigators   +8 more
doaj   +1 more source

Challenges in care of snake envenomation in rural Pakistan: a narrative review

Toxicology Communications, 2023
Snake envenomation remains a neglected tropical disease in Pakistan per the World Health Organization, with approximately 40,000 bites and 8,200 fatalities annually.
Rmaah Memon, Timothy B. Erickson, Charlotte E. Goldfine   +2 more
doaj   +1 more source