Results 31 to 40 of about 3,616 (129)

A phase IV, prospective, observational study of the clinical safety of snake antivenoms

Revista do Instituto de Medicina Tropical de São Paulo, 2021
Snake envenoming is a neglected tropical disease that affects more than 2.7 million people worldwide. The treatment is based on the administration of antivenom composed of heterologous immunoglobulins, species-specific therapy involving the possibility ...
Denise Christie Souto Nogueira, Iara Pinheiro Calil, Roberta Márcia Marques dos Santos, Adebal de Andrade Filho, Gláucia Cota   +4 more
doaj   +1 more source

Viper and cobra venom neutralization by alginate coated multicomponent polyvalent antivenom administered by the oral route. [PDF]

PLoS Neglected Tropical Diseases, 2014
BACKGROUND:Snake bite causes greater mortality than most of the other neglected tropical diseases. Snake antivenom, although effective in minimizing mortality in developed countries, is not equally so in developing countries due to its poor availability ...
Sourav Bhattacharya, Mousumi Chakraborty, Piyasi Mukhopadhyay, P P Kundu, Roshnara Mishra   +4 more
doaj   +1 more source

Snakebites and the Effect of Serum Anti Bisa Ular (SABU) Antivenom at Dr. Hasan Sadikin General Hospital Bandung, Indonesia: an Overview Period 2015–2019

Althea Medical Journal, 2022
Background: Snakebite is considered a global health issue, especially in the Southeast Asian region. However, data regarding snakebite cases in Indonesia are still very limited.
Sharon Noor Alya, Enny Rochmawaty, Achadiyani Achadiyani, Muhammad Hasan Bashari, Hardisiswo Soedjana   +4 more
doaj   +1 more source

Neutralization of the Principal Toxins from the Venoms of Thai Naja kaouthia and Malaysian Hydrophis schistosus: Insights into Toxin-Specific Neutralization by Two Different Antivenoms

Toxins, 2016
Antivenom neutralization against cobra venoms is generally low in potency, presumably due to poor toxin-specific immunoreactivity. This study aimed to investigate the effectiveness of two elapid antivenoms to neutralize the principal toxins purified from
Kae Yi Tan, Choo Hock Tan, Shin Yee Fung, Nget Hong Tan   +3 more
doaj   +1 more source

Identification of antigenic proteins from the venom of Malaysian snakes using immunoprecipitation assay and tandem mass spectrometry (LC-MS/MS)

Heliyon
Snake envenomation poses a significant risk to Malaysians and country visitors. Malaysia witnesses an estimated 650 snake bites per 100,000 population annually.
Preetha Rajendiran, Rakesh Naidu, Iekhsan Othman, Syafiq Asnawi Zainal Abidin   +3 more
doaj   +1 more source

Cross neutralization of Afro-Asian cobra and Asian krait venoms by a Thai polyvalent snake antivenom (Neuro Polyvalent Snake Antivenom). [PDF]

PLoS Neglected Tropical Diseases, 2012
BACKGROUND: Snake envenomation is a serious public health threat in the rural areas of Asian and African countries. To date, the only proven treatment for snake envenomation is antivenom therapy.
Poh Kuan Leong, Si Mui Sim, Shin Yee Fung, Khomvilai Sumana, Visith Sitprija, Nget Hong Tan   +5 more
doaj   +1 more source

A Retrospective Descriptive Analysis of Consultations Provided by the National Poisons Centre Relating to Medicines on the Aotearoa New Zealand Antidote Stocking Guideline, 2020–2025

Emergency Medicine Australasia, Volume 38, Issue 5, October 2026.
ABSTRACT Objective Many antidotes are relatively rare‐use, indication‐specific medicines with a variable evidence base. In Aotearoa New Zealand, there are no national statistics available on their use. This study aimed to characterize the numbers of cases and advice provided by the Aotearoa New Zealand National Poisons Centre (NZNPC) on the use of true
Eeva‐Katri Kumpula, William Boroughf
wiley   +1 more source

Experimental Bothrops atrox envenomation: Efficacy of antivenom therapy and the combination of Bothrops antivenom with dexamethasone. [PDF]

PLoS Neglected Tropical Diseases, 2017
Bothrops atrox snakes are the leading cause of snake bites in Northern Brazil. The venom of this snake is not included in the antigen pool used to obtain the Bothrops antivenom. There are discrepancies in reports on the effectiveness of this antivenom to
Gabriella Neves Leal Santos Barreto, Sâmella Silva de Oliveira, Isabelle Valle Dos Anjos, Hipocrates de Menezes Chalkidis, Rosa Helena Veras Mourão, Ana Maria Moura-da-Silva, Ida Sigueko Sano-Martins, Luis Roberto de Camargo Gonçalves   +7 more
doaj   +1 more source

Evaluating Antivenom Efficacy against Echis carinatus Venoms—Screening for In Vitro Alternatives

Toxins, 2022
In India, polyvalent antivenom is the mainstay treatment for snakebite envenoming. Due to batch-to-batch variation in antivenom production, manufacturers have to estimate its efficacy at each stage of IgG purification using the median effective dose ...
Siddharth Bhatia, Avni Blotra, Karthikeyan Vasudevan   +2 more
doaj   +1 more source

Evaluation of the properties of Bungarus caeruleus venom and checking the efficacy of antivenom used in Bangladesh for its bite treatment

Toxicon: X, 2023
As a disaster-prone country with unique geographical features, snake biting is a major public health concern in Bangladesh. The primary reasons of mortality from snakebite include late presentation to the hospital, low efficacy of antivenom, and a lack ...
Md Jahangir Alam, Md.Mahmudul.Hasan Maruf, Md Asif Iqbal, Mahedi Hasan, Md Sohanur.Rahman Sohan, Md Ragib Shariar, Ibrahim Khalil Al Haidar, Mohammad Abdul Wahed Chowdhury, Aniruddha Ghose, Kazi Md Faisal Hoque, Md Abu Reza   +10 more
doaj   +1 more source