Results 51 to 60 of about 3,616 (129)

Immune response to snake envenoming and treatment with antivenom; complement activation, cytokine production and mast cell degranulation.

PLoS Neglected Tropical Diseases, 2013
BackgroundSnake bite is one of the most neglected public health issues in poor rural communities worldwide. In addition to the clinical effects of envenoming, treatment with antivenom frequently causes serious adverse reactions, including ...
Shelley F Stone, Geoffrey K Isbister, Seyed Shahmy, Fahim Mohamed, Chandana Abeysinghe, Harendra Karunathilake, Ariaranee Ariaratnam, Tamara E Jacoby-Alner, Claire L Cotterell, Simon G A Brown   +9 more
doaj   +1 more source

Does the traditional snakebite severity score correctly classify envenomated patients? [PDF]

Clinical and Experimental Emergency Medicine, 2016
Objective This study aims to help set domestic guidelines for administration of antivenom to envenomated patients after snakebites. Methods This retrospective observational case series comprised 128 patients with snake envenomation.
Seungho Kang, Jeongmi Moon, Byeongjo Chun   +2 more
doaj   +1 more source

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

The FEBS Journal, Volume 293, Issue 13, Page 3881-3898, July 2026.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin, Sumit Bhutada, Suneel S. Apte   +2 more
wiley   +1 more source

Inflammation induced by snake venoms optimizes envenomation

The Journal of Physiology, Volume 604, Issue 14, Page 5831-5852, 15 July 2026.
Abstract figure legend Schematic illustrating mechanisms underlying direct vascular absorption and subsequent movement of venom toxins into the tissues consequent to snakebite. A, snakebite into prey deposits venom toxins into the tissue interstitium, with the venom then causing acute inflammation primarily in venules.
Dirk F. van Helden, Neil Spratt, Peter J. Dosen, Sally A. McFadden, John Holdsworth, Daniel J Beard, Kirsten Coupland, Phillip Jobling, Todd A. Hardy, Derek R. Laver   +9 more
wiley   +1 more source

Diversity of Micrurus snake species related to their venom toxic effects and the prospective of antivenom neutralization.

PLoS Neglected Tropical Diseases, 2010
BackgroundMicrurus snake bites can cause death by muscle paralysis and respiratory arrest, few hours after envenomation. The specific treatment for coral snake envenomation is the intravenous application of heterologous antivenom and, in Brazil, it is ...
Gabriela D Tanaka, Maria de Fátima D Furtado, Fernanda C V Portaro, Osvaldo Augusto Sant'Anna, Denise V Tambourgi   +4 more
doaj   +1 more source

Diagnosing Syndrome‐Like Microangiopathic Hemolytic Anemia After Pit Viper Envenomation: Overcoming Laboratory Gaps in a Resource‐Limited Setting: A Case Report From Nepal

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Snakebite envenomation remains a significant yet often overlooked health challenge in Nepal, particularly in its rural and hilly regions. While venom‐induced consumption coagulopathy (VICC) is commonly observed with viper bites, microangiopathic hemolytic anemia (MAHA) is an extremely rare complication, especially with green pit vipers ...
Prabhat Kaphle, Pukar Gupta, Sarjan Shrestha, Neeru Diyali, Raj Kumar Koirala, Amrita Shrestha, Dhanlaxmi Giri, Nabin Pahari, Anil Kumar Sah, Kamal Hamal, Sujan Bohara   +10 more
wiley   +1 more source

A review on Snake Bite and Management in Nigeria- The Need for The Development of a Snake Bite Strategy

Sokoto Journal of Medical Laboratory Science, 2020
Snake-bites is a global public health and a well-known medical emergency in many parts of the world, especially in rural areas. The aim of this review is to look critically at the challenge of snake Bite in Nigeria and to advocate for the development of ...
Babangida, S. , Erhabor, O. , Erhabor, T. , Adias, T.C.
doaj  

Snake bite in South Asia: a review. [PDF]

PLoS Neglected Tropical Diseases, 2010
Snake bite is one of the most neglected public health issues in poor rural communities living in the tropics. Because of serious misreporting, the true worldwide burden of snake bite is not known.
Emilie Alirol, Sanjib Kumar Sharma, Himmatrao Saluba Bawaskar, Ulrich Kuch, François Chappuis   +4 more
doaj   +1 more source

Protein design and RNA design: Perspectives

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract Advances in deep learning and generative modeling have transformed the landscape of protein and RNA design, enabling rapid and precise creation of novel biomolecules with tailored structures and functions. In protein design, generative deep learning frameworks now support backbone generation, sequence optimization, and joint sequence–structure
Xi Chen, Xu Dai, Peilong Lu
wiley   +1 more source

A Single-Center Review of Cases to Understand the Indian Polyvalent Antivenom Use in Hump-Nosed Pit Viper Bites in South India

Journal of Emergencies, Trauma and Shock
Introduction: India, with nearly 60 venomous snake species, has just one commercially available antivenom, the Indian polyvalent antivenom (IPAV). The hump-nosed pit viper (Hypnale hypnale), an indigenous venomous snake, causes considerable morbidity and
Siju V. Abraham, Sarah Paul, Martin V. Paul, Clint Davis, Aboobacker Mohamed Rafi, Appu Suseel, Deo Mathew, C. K. Kassyap, Rajeev Punchalil Chathappan   +8 more
doaj   +1 more source