Results 1 to 10 of about 147,662 (251)
Fertility & Reproduction, 2022 Background: Endometriosis is an under-recognised and often misdiagnosed chronic disease that affects one in ten women. It occurs when cells similar to those that line a uterus grow in other parts of the body, usually around the pelvis.
Kerryn L. GARRETT +11 more
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Nature Communications, 2021 How ROS levels are regulated in cancer stem cells and their contribution to cancer resistance is currently not clear. Here, the authors show that prohibitin regulates mitochondrial ROS production stabilizing the peroxidase PRDX3 and this accounts for ...
Haohao Huang +23 more
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Proteomes, 2020 PromarkerD is a proteomics derived test for predicting diabetic kidney disease that measures the concentrations of three plasma protein biomarkers, APOA4, CD5L and IBP3.
Scott Bringans +4 more
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Foresight in clinical proteomics: current status, ethical considerations, and future perspectives
Open Research Europe, 2023 With the advent of robust and high-throughput mass spectrometric technologies and bioinformatics tools to analyze large data sets, proteomics has penetrated broadly into basic and translational life sciences research.
Filip Mundt +9 more
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Nature Communications, 2021 Dynamic assembly and disassembly of primary cilia is critical for tissue development and homeostasis. Here the authors identify lysophosphatidic acid (LPA) as a physiological extracellular factor that initiates cilia disassembly through both YAP/TAZ ...
Huai-Bin Hu +17 more
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SPS’ Digest: the Swiss Proteomics Society selection of proteomics articles [PDF]
, 2005 Despite the consolidation of the specialized proteomics literature around a few established journals, such as Proteomics, Molecular and Cellular Proteomics, and the Journal of Proteome Research, a lot of information is still spread in many different ...
Palagi Graf, Patricia +19 more
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Clinical Proteomics, 2017 Background The aim was to improve upon an existing blood-based colorectal cancer (CRC) test directed to high-risk symptomatic patients, by developing a new CRC classifier to be used with a new test embodiment.
Lisa J. Croner +8 more
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Illuminating phenotypic drug responses of sarcoma cells to kinase inhibitors by phosphoproteomics
Molecular Systems Biology, 2023 Kinase inhibitors (KIs) are important cancer drugs but often feature polypharmacology that is molecularly not understood. This disconnect is particularly apparent in cancer entities such as sarcomas for which the oncogenic drivers are often not clear. To
Chien-Yun Lee +12 more
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PROTEINCHALLENGE: Crowd sourcing in proteomics analysis and software development [PDF]
, 2013 In large-scale proteomics studies there is a temptation, after months of experimental work, to plug resulting data into a convenient—if poorly implemented—set of tools, which may neither do the data justice nor help answer the scientific question.
Falkenberg, Heiner +6 more
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