Results 11 to 20 of about 278,188 (259)

Proteomics

open access: yesJournal of Education, Health and Sport, 2021
Proteomics is a branch of molecular biology that deals with the identification and quantification of proteins in living objects, as well as the analysis of protein functions and their interactions. Proteomics is studied by proteins that are expressed
S. Dolomatov, V. Kazakova, W. Zukow
doaj   +3 more sources

AlphaPeptDeep: a modular deep learning framework to predict peptide properties for proteomics

open access: yesNature Communications, 2022
Deep learning (DL) has been frequently used in mass spectrometry-based proteomics but there is still a lot of potential. Here, the authors develop a framework that enables building DL models to predict arbitrary peptide properties with only a few lines ...
Wen-Feng Zeng   +8 more
doaj   +1 more source

GCG inhibits SARS-CoV-2 replication by disrupting the liquid phase condensation of its nucleocapsid protein

open access: yesNature Communications, 2021
Coronavirus nucleocapsid (N) protein is important for viral genome packaging and virion assembly. Here the authors show that natural chemical (-)-gallocatechin gallate (GCG) disrupts the liquid–liquid phase separation of N and inhibits SARS-CoV-2 ...
Ming Zhao   +20 more
doaj   +1 more source

Nanotechnologies in Proteomics [PDF]

open access: yesChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Yuri D, Ivanov   +3 more
openaire   +2 more sources

Highly sensitive CE-ESI-MS analysis of N-glycans from complex biological samples

open access: yesNature Communications, 2019
In-depth characterization of complex glycomes is complicated by the immense structural diversity of glycans. Here, the authors present a mass spectrometry-based strategy for untargeted, sensitive glycan profiling and identify 167 N-glycan compositions in
Guinevere S. M. Lageveen-Kammeijer   +7 more
doaj   +1 more source

The Endogenous Metabolite Glycerophosphocholine Promotes Longevity and Fitness in Caenorhabditis elegans

open access: yesMetabolites, 2022
Metabolism and aging are closely connected. The choline derivative glycerophosphocholine (GPC), an important precursor of the neurotransmitter acetylcholine, plays important roles in brain and nervous system function.
Jia-Yu Liu   +11 more
doaj   +1 more source

Redox Proteomics [PDF]

open access: yesAntioxidants & Redox Signaling, 2012
Proteins are major targets of reactive oxygen and nitrogen species (ROS/RNS) and numerous post-translational, reversible or irreversible modifications have been characterized, which may lead to a change in the structure and/or function of the oxidized protein.
D. A. Butterfield, I. Dalle-Donne
openaire   +2 more sources

Organelle Proteomics [PDF]

open access: yesCurrent Protocols in Protein Science, 2006
AbstractThis unit describes strategies for studying the proteomes of organelles, which is one example of targeted proteomics. It relies heavily on previously published units dealing with organelle preparation, protein solubilization, and proteomics techniques. A specific commentary for organelle proteomics is provided.
Lescuyer, Pierre   +3 more
openaire   +5 more sources

Combining LOPIT with differential ultracentrifugation for high-resolution spatial proteomics

open access: yesNature Communications, 2019
Spatial proteomics allows studying cellular protein localisations at system-wide scale. Here, the authors show that combining the previously developed hyperLOPIT method with differential centrifugation yields protein localisation maps at suborganellar ...
Aikaterini Geladaki   +8 more
doaj   +1 more source

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