Results 11 to 20 of about 331,596 (261)

Proteomics beyond trypsin [PDF]

, 2015
Peptide-centered shotgun analysis of proteins has been the core technology in mass spectrometry based proteomics and has enabled numerous biological discoveries, such as the large-scale charting of protein-protein interaction networks, the quantitative ...
Tsiatsiani, Liana, Heck, Albert J R, Albert J. R. Heck, Sub Biomol.Mass Spectrometry & Proteom., Liana Tsiatsiani, Biomolecular Mass Spectrometry and Proteomics, Sub Biomol.Mass Spect. and Proteomics   +6 more
core   +1 more source

Reconciling proteomics with next generation sequencing [PDF]

, 2015
Both genomics and proteomics technologies have matured in the last decade to a level where they are able to deliver system-wide data on the qualitative and quantitative abundance of their respective molecular entities, that is DNA/RNA and proteins.
Low, Teck Yew, Heck, Albert Jr, Sub Biomol.Mass Spectrometry & Proteom., Biomolecular Mass Spectrometry and Proteomics, Sub Biomol.Mass Spect. and Proteomics   +4 more
core   +1 more source

PROTEINCHALLENGE: Crowd sourcing in proteomics analysis and software development [PDF]

, 2013
In large-scale proteomics studies there is a temptation, after months of experimental work, to plug resulting data into a convenient—if poorly implemented—set of tools, which may neither do the data justice nor help answer the scientific question.
Falkenberg, Heiner, Mageean, Craig J., Khoudoli, Guennadi A., Linding, Rune, Dyrlund, Thomas Franck, Martin, Sarah F., Dyrlund, Thomas F.   +6 more
core   +1 more source

Environmental and structural proteomics

, 2015
[No abstract available]sem informação10413sem informaçãosem informaçãoRenella, G., Ogunseitan, O., Giagnoni, L., Arenella, M., (2014) Soil Biol Biochem, 69, p.
Ramos, Carlos H.I., Capelo, José Luis, Arruda, Marco A.Z., Lodeiro, Carlos   +3 more
core   +1 more source

Proteomics of industrial fungi: trends and insights for biotechnology [PDF]

, 2010
Filamentous fungi are widely known for their industrial applications, namely, the production of food-processing enzymes and metabolites such as antibiotics and organic acids.
Oliveira, J.M., Graaff, L.H., de, Leo H. de Graaff, José Miguel P. Ferreira de Oliveira   +3 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Next-generation proteomics: towards an integrative view of proteome dynamics

, 2013
Next-generation sequencing allows the analysis of genomes, including those representing disease states. However, the causes of most disorders are multifactorial, and systems-level approaches, including the analysis of proteomes, are required for a more ...
Heck, A.J.R., Munoz-Peralta, J., Altelaar, A.F.M., Sub Biomol.Mass Spectrometry & Proteom., Biomolecular Mass Spectrometry and Proteomics, Sub Biomol.Mass Spect. and Proteomics   +5 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

PRIME-XS, a European infrastructure for proteomics

, 2014
The PRIME-XS consortium is a pan-European infrastructure for proteomics. As a prologue to this special issue of Molecular & Cellular Proteomics on the research activities of the PRIME-XS consortium, we, as the guest editors of this issue, provide an ...
Olsen, Jesper V, Sub Algemeen Biomolecular Science, Heck, Albert J R, Molecular Pharmacy, Aebersold, Ruedi, Sub Biomol.Mass Spectrometry & Proteom., Raijmakers, Reinout, Biomolecular Mass Spectrometry and Proteomics, Sub Biomol.Mass Spect. and Proteomics   +8 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source