Results 11 to 20 of about 394,740 (302)
Journal of Education, Health and Sport, 2021 Proteomics is a branch of molecular biology that deals with the identification and quantification of proteins in living objects, as well as the analysis of protein functions and their interactions. Proteomics is studied by proteins that are expressed
S. Dolomatov, V. Kazakova, W. Zukow
doaj +3 more sources
Fertility & Reproduction, 2022 Background: Endometriosis is an under-recognised and often misdiagnosed chronic disease that affects one in ten women. It occurs when cells similar to those that line a uterus grow in other parts of the body, usually around the pelvis.
Kerryn L. GARRETT +11 more
doaj +1 more source
Nature Communications, 2021 How ROS levels are regulated in cancer stem cells and their contribution to cancer resistance is currently not clear. Here, the authors show that prohibitin regulates mitochondrial ROS production stabilizing the peroxidase PRDX3 and this accounts for ...
Haohao Huang +23 more
doaj +1 more source
Proteomes, 2020 PromarkerD is a proteomics derived test for predicting diabetic kidney disease that measures the concentrations of three plasma protein biomarkers, APOA4, CD5L and IBP3.
Scott Bringans +4 more
doaj +1 more source
Nature Communications, 2021 Dynamic assembly and disassembly of primary cilia is critical for tissue development and homeostasis. Here the authors identify lysophosphatidic acid (LPA) as a physiological extracellular factor that initiates cilia disassembly through both YAP/TAZ ...
Huai-Bin Hu +17 more
doaj +1 more source
Clinical Proteomics, 2017 Background The aim was to improve upon an existing blood-based colorectal cancer (CRC) test directed to high-risk symptomatic patients, by developing a new CRC classifier to be used with a new test embodiment.
Lisa J. Croner +8 more
doaj +1 more source
Illuminating phenotypic drug responses of sarcoma cells to kinase inhibitors by phosphoproteomics
Molecular Systems Biology, 2023 Kinase inhibitors (KIs) are important cancer drugs but often feature polypharmacology that is molecularly not understood. This disconnect is particularly apparent in cancer entities such as sarcomas for which the oncogenic drivers are often not clear. To
Chien-Yun Lee +12 more
doaj +1 more source
Transcriptionally imprinted glycomic signatures of acute myeloid leukemia
Cell & Bioscience, 2023 Background Acute myeloid leukemia (AML) is a genetically and phenotypically heterogeneous disease that has been suffering from stagnant survival curves for decades.
Constantin Blöchl +4 more
doaj +1 more source
Open Research Europe, 2023 With the advent of robust and high-throughput mass spectrometric technologies and bioinformatics tools to analyze large data sets, proteomics has penetrated broadly into basic and translational life sciences research.
Filip Mundt +9 more
doaj +1 more source