Results 41 to 50 of about 394,740 (302)

Toward an Optimized Workflow for Middle-Down Proteomics [PDF]

, 2017
Mass spectrometry (MS)-based proteomics workflows can crudely be classified into two distinct regimes, targeting either relatively small peptides (i.e., 0.7 kDa < Mw < 3.0 kDa) or small to medium sized intact proteins (i.e., 10 kDa < Mw < 30 kDa ...
Heck, AJR, Shabaz Mohammed (237215), Marino, Fabio, Mohammed, Shabaz, Shabaz Mohammed, Cristobal, A, Cristobal, Alba, Harm Post (1973920), van den Toorn, Henk W.P., Harm Post, van den Toorn, HWP, Fabio Marino, Post, Harm, Alba Cristobal, Mohammed, S, Mohammed, Shabaza, Heck, Albert J R, Albert J. R. Heck (9680), Sub Biomol.Mass Spectrometry & Proteom., Henk W. P. van den Toorn, Biomolecular Mass Spectrometry and Proteomics, Post, H, Henk W. P. van den Toorn (2227249), Heck, Albert J.R., Albert J. R. Heck, Alba Cristobal (659462), Fabio Marino (1405816), Marino, F, Cristobal Gonzalez de Durana, Alba, van den Toorn, Henk W P, Afd Biomol.Mass Spect. and Proteomics   +30 more
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Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Proteomics of industrial fungi: trends and insights for biotechnology [PDF]

, 2010
Filamentous fungi are widely known for their industrial applications, namely, the production of food-processing enzymes and metabolites such as antibiotics and organic acids.
Oliveira, J.M., Graaff, L.H., de, Leo H. de Graaff, José Miguel P. Ferreira de Oliveira   +3 more
core   +1 more source

Application of a validated prognostic plasma protein biomarker test for renal decline in type 2 diabetes to type 1 diabetes: the Fremantle Diabetes Study Phase II

Clinical Diabetes and Endocrinology
Background There are scant data relating to prognostic biomarkers for chronic kidney disease (CKD) complicating type 1 diabetes. The aim of this study was to assess the performance of the plasma protein biomarker-based PromarkerD test developed and ...
Timothy M. E. Davis, Wendy A. Davis, Scott D. Bringans, James K. C. Lui, Tasha S. C. Lumbantobing, Kirsten E. Peters, Richard J. Lipscombe   +6 more
doaj   +1 more source

Proteomes: A New Proteomic Journal [PDF]

Proteomes, 2012
In the early years of proteomics, mass spectrometry served only as a technique in protein chemistry facilitating the characterization of purified proteins and mapping their posttranslational modifications (PTMs). A bit later this technique almost completely replaced Edman degradation and amino acid analysis.
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Quantitative proteomics in resected renal cancer tissue for biomarker discovery and profiling [PDF]

, 2014
BACKGROUND: Proteomics-based approaches for biomarker discovery are promising strategies used in cancer research. We present state-of-art label-free quantitative proteomics method to assess proteome of renal cell carcinoma (RCC) compared with noncancer ...
J T-J Huang, Bray, S E, Fleming, S., Lamont, D J, D J Lamont, Zakikhani, P, P Zakikhani, M A V Mudaliar, Atrih, A, S Fleming, Zakikhani, P., Lamont, D. J., Barton, G.; id_orcid, G Nabi, G Barton, A Atrih, Bray, S. E., Barton, G, Huang, J. T.-J.; id_orcid, Mudaliar, M. A. V., Atrih, A., Fleming, S, Nabi, G, Nabi, G., Huang, J T-J, S E Bray, Mudaliar, M A V   +26 more
core   +1 more source

Functional proteomics

Clinica Chimica Acta, 2005
With the increase in the number of genome sequencing projects, there is a concomitant exponential growth in the number of protein sequences whose function is still unknown. Functional proteomics constitutes an emerging research area in the proteomic field whose approaches are addressed towards two major targets: the elucidation of the biological ...
MONTI, MARIA, ORRU S, PAGNOZZI D, PUCCI, PIETRO   +3 more
openaire   +4 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Investigating molecular factors regulating cancer biology: from proteomics to multi-omics [PDF]

, 2019
Recent technological advances in studying proteins using mass spectrometry (MS-based proteomics) have empowered in-depth profiling of the human proteome, such that MS-based proteomics can nowadays identify disease-specific proteins indicative of a ...
Ressa, Anna, Biomolecular Mass Spectrometry and Proteomics, Afd Biomol.Mass Spect. and Proteomics   +2 more
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