Results 31 to 40 of about 576,501 (302)

Quantitative profiling of the human substantia nigra proteome from laser-capture microdissected FFPE tissue [PDF]

, 2020
Laser-capture microdissection (LCM) allows the visualization and isolation of morphologically distinct subpopulations of cells from heterogeneous tissue specimens.
Griesser, Eva, Lamond, Angus I., Lenter, Martin, Stierstorfer, Birgit, Ten Have, Sara, Wyatt, Hannah   +5 more
core   +3 more sources

Differential neuroproteomic and systems biology analysis of spinal cord injury [PDF]

, 2016
Acute spinal cord injury (SCI) is a devastating condition with many consequences and no known effective treatment. Although it is quite easy to diagnose traumatic SCI, the assessment of injury severity and projection of disease progression or recovery ...
Bramlett, Helen M, Das, Jyotirmoy H, Dietrich, W. Dalton, Moghieb, Ahmed, Selig, Tyler, Wang, Kevin K. W, Wang, Michael S, Yang, Zhihui, Yost, Richard A   +8 more
core   +2 more sources

Proteomics Discovery of Disease Biomarkers

Biomarker Insights, 2008
Recent technological developments in proteomics have shown promising initiatives in identifying novel biomarkers of various diseases. Such technologies are capable of investigating multiple samples and generating large amount of data end-points. Examples
Mamoun Ahram, Emanuel F. Petricoin
doaj   +2 more sources

Current challenges in software solutions for mass spectrometry-based quantitative proteomics [PDF]

, 2012
This work was in part supported by the PRIME-XS project, grant agreement number 262067, funded by the European Union seventh Framework Programme; The Netherlands Proteomics Centre, embedded in The Netherlands Genomics Initiative; The Netherlands ...
A Alexandridou, A Gruhler, A Leitner, A Michalski, A Panchaud, A Thompson, A Wolf-Yadlin, AD Polpitiya, AHP America, AI Nesvizhskii, AI Nesvizhskii, AI Nesvizhskii, AJR Heck, Albert J. R. Heck, AM Mayampurath, B Breukelen van, B Carrillo, B Ma, B Macek, B Schwanhäusser, B Zybailov, BAP Roxas, Bas van Breukelen, BO Keller, C Christin, C Ji, C Kumar, CH Becker, CK Frese, C–C Tsou, D Chelius, D Hoof Van, D MacDougall, D Tsur, D Valkenborg, DH Lundgren, DK Han, DL Swaney, DL Tabb, DL Tabb, DM Good, DN Perkins, E Deutsch, E Qeli, EL Hendrickson, G Audi, GL Finney, H Lam, H Lam, H Liu, H Steen, H Steen, I Beer, IP Shadforth, J Cox, J Cox, J Elias, J Gouw, J Grossmann, J Klimek, J Listgarten, J Meija, J Rappsilber, J Seidler, J Zhang, JC Silva, JF Kellie, JF Timms, JV Olsen, K Flikka, K Kultima, K Podwojski, KA Neilson, KC Hansen, KL Simpson, L Martens, L Ting, LF Waanders, LK Iwai, LN Mueller, M Bantscheff, M Bantscheff, M Bern, M Junqueira, M Kohl, M Mann, M Sandin, M Senko, M Unlü, M Vandenbogaert, MA Baldwin, MA Grobei, MA Kuzyk, MC Codrea, ME Belov, ME Sardiu, MH Elliott, MJ MacCoss, MM Savitski, MW Duncan, N Colaert, N Mischerikow, N Wang, NM Griffin, OA Mirgorodskaya, P Lu, P Mallick, P Mortensen, Pedro R. Cutillas, Peter R. Baker, PJ Boersema, PL Ross, PR Baker, PR Cutillas, PR Cutillas, R Aebersold, R Clarke, R Matthiesen, R Matthiesen, R Purves, R Usaite, R Zhang, RA Bradshaw, RD Smith, RE Moore, RJ Chalkley, RJ Chalkley, RJ Jacob, S Cappadona, S Cappadona, S Carr, S Dasari, S Houel, S Julka, S Ong, S-E Ong, SA Beausoleil, SA Gerber, Salvatore Cappadona, SJ Callister, SK Park, SP Gygi, SY Ow, T Shinkawa, TM Annesley, TS Collier, TT Aye, V Faca, V Lange, VG Tusher, VP Andreev, W Weiss, W Yan, W Zhu, WM Old, WX Schulze, X Yang, Y Ishihama, Y Oda, YJ Kim, Z Khan, Z Khan, Z-Q Ma   +162 more
core   +2 more sources

Proteomics: in pursuit of effective traumatic brain injury therapeutics [PDF]

, 2015
Effective traumatic brain injury (TBI) therapeutics remain stubbornly elusive. Efforts in the field have been challenged by the heterogeneity of clinical TBI, with greater complexity among underlying molecular phenotypes than initially conceived.
Ahmed F, Andrew K Ottens, Bales JW, Begum G, Berger RP, Bonislawski DP, Bos R, Boulenguez P, Boutte AM, Brandner S, Brandner S, Campos-Martorell M, Cortes DF, Crawford F, Dachir S, Daoud H, Evans TM, Gackiere F, Gonzalez MI, Guingab-Cagmat JD, Gyorgy A, Gyorgy AB, Jaramillo ML, Jeter CB, Kabadi SV, Kabadi SV, Kahle KT, Kumar A, Levi S, Li BC, Liang J, Liang J, Lin WM, Loane DJ, Loov C, Lopez NE, Maier O, Manley GT, Maurer MH, Mehan ND, Mohseni S, Mondello S, Mondello S, Ottens AK, Ottens AK, Pavel N Lizhnyak, Prieto DA, Rau TF, Rosenfeld JV, Saatman KE, Schmid KE, Shen S, Shen Y, Siman R, Siman R, Sun C, Talley Watts L, Tsai YT, Wagner AK, Wu P, Xiong Y, Yu W, Zetterberg H, Zgavc T, Zhou XM   +64 more
core   +2 more sources

Combining LOPIT with differential ultracentrifugation for high-resolution spatial proteomics

Nature Communications, 2019
Spatial proteomics allows studying cellular protein localisations at system-wide scale. Here, the authors show that combining the previously developed hyperLOPIT method with differential centrifugation yields protein localisation maps at suborganellar ...
Aikaterini Geladaki, Nina Kočevar Britovšek, Lisa M. Breckels, Tom S. Smith, Owen L. Vennard, Claire M. Mulvey, Oliver M. Crook, Laurent Gatto, Kathryn S. Lilley   +8 more
doaj   +1 more source

Platelet proteomics [PDF]

Journal of Thrombosis and Haemostasis, 2003
As anucleate cell particles, platelets do not lend themselves to analysis by traditional cell and molecular biology techniques. Moreover, while valuable information may be gleaned from studies of messenger RNA in platelets, the rapid events in platelets are not governed by or dependent on alterations in gene expression.
P B, Maguire, D J, Fitzgerald
openaire   +2 more sources

Proteomic Approach for Extracting Cytoplasmic Proteins from Streptococcus sanguinis using Mass Spectrometry [PDF]

, 2017
Streptococcus sanguinis is a commensal and early colonizer of oral cavity as well as an opportunistic pathogen of infectious endocarditis. Extracting the soluble proteome of this bacterium provides deep insights about the physiological dynamic changes ...
Elrami, Fadi, Nelson, Kristina, Xu, Ping
core   +3 more sources

Synaptosome Proteomics [PDF]

, 2007
Our knowledge of the complex synaptic proteome and its relationship to physiological or pathological conditions is rapidly expanding. This has been greatly accelerated by the application of various evolving proteomic techniques, enabling more efficient protein resolution, more accurate protein identification, and more comprehensive characterization of ...
Fengju, Bai, Frank A, Witzmann
openaire   +2 more sources

Biomarkers of inflammatory arthritis and proteomics [PDF]

, 2013
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FitzGerald, Oliver, R., Stephen, S., Opeyemi, Staunton, Lisa   +3 more
core   +3 more sources