Results 61 to 70 of about 331,596 (261)

Proteomics studies in inner ear disorders: Pathophysiology and biomarkers [PDF]

open access: yes, 2015
Although proteomics has been exploited in a wide range of diseases for identification of biomarkers and pathophysiological mechanisms, there are still biomedical disciplines such as otology where proteomics platforms are underused due to technical ...
Kobeissy, Firas H.   +4 more
core   +1 more source

Proteomics [PDF]

open access: yesJournal of Biomedicine and Biotechnology, 2010
Garcia, Benjamin A.   +4 more
openaire   +2 more sources

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Identification of screening biomarkers for chromosomal anomalies and pregnancy-related disorder using quantitative plasma proteomics [PDF]

open access: yes, 2011
Due to the risk associated with invasive procedures, a large research effort has been expended to the development of risk free alternatives. Current results indicate that we may be approaching the long sought goal of Non-Invasive Prenatal Diagnosis (NIPD)
Kolla, Varaprasad
core   +1 more source

aliyurtsevenn/COVID-19-Plasma-Proteomics: COVID19-Proteomics

open access: yes, 2022
Code to implement bioinformatics analysis for the COVID-19 plasma proteomics ...
Ali Yurtseven
core   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Proteomics of transcription factors

open access: yes, 2011
Peptide mass spectrometry (MS) is an invaluable analytical method in biological and medical research. It is the only technique that, when integrated with liquid chromatography (LC) and database search tools, allows a highly sensitive qualitative ...
Mischerikow, N.   +2 more
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Application of chemical proteomics to biomarker discovery in cardiac research

open access: yes, 2010
This thesis is primarily focused on (i.) exploring chemical probes to increase sensitivity and specificity for the investigation of low abundant cardiac proteins applicable to both biology and biomarker discovery, and (ii.) exploiting different aspects ...
Dep Farmaceutische wetenschappen   +2 more
core  

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