Results 21 to 30 of about 128,459 (218)

Development and characterization of single domain monoclonal antibody against programmed cell death ligand-1; as a cancer inhibitor candidate [PDF]

Iranian Journal of Basic Medical Sciences, 2022
Objective(s): One of the important interactions in controlling the human immune system is the reaction between checkpoint proteins such as programmed cell death-1 (PD-1) and its ligand, PD-L1.
Akbar Oghalaei, Feriedon Mahbudi, Fatemeh Rahimi Jamnani, Somayeh Piri-Gavgani, Fatemeh Kazemi-Lomedasht, Aida Hassanzadeh-Eskafi, Delavar Shahbazzadeh, Ahmad Adeli, Yeganeh Talebkhan, Mahdi Behdani   +9 more
doaj   +1 more source

Comparative Studies of the Venom of a New Taipan Species, Oxyuranus temporalis, with Other Members of Its Genus

Toxins, 2014
Taipans are highly venomous Australo-Papuan elapids. A new species of taipan, the Western Desert Taipan (Oxyuranus temporalis), has been discovered with two specimens housed in captivity at the Adelaide Zoo.
Carmel M. Barber, Frank Madaras, Richard K. Turnbull, Terry Morley, Nathan Dunstan, Luke Allen, Tim Kuchel, Peter Mirtschin, Wayne C. Hodgson   +8 more
doaj   +1 more source

On the occurrence of Persian Gulf Sea Snake, Hydrophis lapemoides (Gray, 1849) (Reptilia, Squamata, Elapidae, Hydrophiinae), along the coast of Bangladesh [PDF]

Check List, 2021
We provide the first evidence of the presence of the Persian Gulf Sea Snake, Hydrophis lapemoides (Gray, 1849), along the coast of Bangladesh. This species was assumed to exist in there, but neither specimens nor confirmed observations exist until now ...
Mohammad Abdul Wahed Chowdhury, Md. Rafiqul Islam, Abdul Auawal, Najmul Hasan, Harij Uddin, Ibrahim Khalil Al Haidar   +5 more
doaj   +3 more sources

Monkeying around with venom: an increased resistance to α-neurotoxins supports an evolutionary arms race between Afro-Asian primates and sympatric cobras

BMC Biology, 2021
Background Snakes and primates have a multi-layered coevolutionary history as predators, prey, and competitors with each other. Previous work has explored the Snake Detection Theory (SDT), which focuses on the role of snakes as predators of primates and ...
Richard J. Harris, K. Anne-Isola Nekaris, Bryan G. Fry   +2 more
doaj   +1 more source

ANTIVIRAL EFFECT OF THE EGYPTIAN BEE VENOM (BV) AND ITS FRACTION (PLA2) ON INFLUENZA VIRUS: IN-VITRO STUDY [PDF]

Journal of the Egyptian Society of Parasitology, 2020
Influenza is a viral infection that attacks the respiratory system. For most people, the fludisappears on its own but sometimes the flu and its complications can be deadly. This studyestablished a new trend to treat Influenza virus by using bee venom and
AYMAN T. A. MORSY, WALAA H. SALAMA, NORHAN M. ELASMY, ABIR A. ELFIKY   +3 more
doaj   +1 more source

A symmetry or asymmetry: Functional and compositional comparison of venom from the left and right glands of the Indochinese spitting cobra (Naja siamensis)

Toxicon: X, 2020
Contralaterally positioned maxillary (upper jaw) venom glands in snakes are mechanically independent, being able to discharge venom from either gland separately.
Richard J. Harris, Christina N. Zdenek, Amanda Nouwens, Charlotte Sweeney, Nathan Dunstan, Bryan G. Fry   +5 more
doaj   +1 more source

In vivo immunotherapy of lung cancer using cross-species reactive vascular endothelial growth factor nanobodies [PDF]

Iranian Journal of Basic Medical Sciences, 2017
Objective(s): Lung cancer is the main leading cause of cancer death worldwide. Angiogenesis is the main step in proliferation and spreading of tumor cells.
vFatemeh Kazemi-Lomedasht v, Kamran Pooshang-Bagheri, Mahdi Habibi-Anbouhi, Ensiyeh Hajizadeh-Safar, Delavar Shahbazzadeh, Hasan Mirzahosseini, Mahdi Behdani   +6 more
doaj   +1 more source

Coagulotoxic Cobras: Clinical Implications of Strong Anticoagulant Actions of African Spitting Naja Venoms That Are Not Neutralised by Antivenom but Are by LY315920 (Varespladib)

Toxins, 2018
Snakebite is a global tropical disease that has long had huge implications for human health and well-being. Despite its long-standing medical importance, it has been the most neglected of tropical diseases.
Mátyás A. Bittenbinder, Christina N. Zdenek, Bianca op den Brouw, Nicholas J. Youngman, James S. Dobson, Arno Naude, Freek J. Vonk, Bryan G. Fry   +7 more
doaj   +1 more source

Isolation and Pharmacological Characterization of α-Elapitoxin-Ot1a, a Short-Chain Postsynaptic Neurotoxin from the Venom of the Western Desert Taipan, Oxyuranus temporalis

Toxins, 2016
Taipans (Oxyuranus spp.) are elapids with highly potent venoms containing presynaptic (β) and postsynaptic (α) neurotoxins. O. temporalis (Western Desert taipan), a newly discovered member of this genus, has been shown to possess venom which displays ...
Carmel M. Barber, Muhamad Rusdi Ahmad Rusmili, Wayne C. Hodgson   +2 more
doaj   +1 more source

Webslinger vs. Dark Knight: First record of a false widow spider Steatoda nobilis preying on a pipistrelle bat in Britain

Ecosphere, 2022
The noble false widow spider Steatoda nobilis continues to expand its range globally with possible implications for public health and native species. Of the European Union list of 66 species of invasive plants and animals, none are spiders. S. nobilis is
John P. Dunbar, Aiste Vitkauskaite, Colin Lawton, Ben Waddams, Michel M. Dugon   +4 more
doaj   +1 more source