Results 41 to 50 of about 115,629 (246)

Innovations in Pedriatic Cradiopulmonary Bypass: a continuous process of quality improvement [PDF]

open access: yes, 2011
Cardiopulmonary bypass (CPB) is defined as a technique that temporarily replaces the function of the heart and lungs, maintaining an adequate blood circulation and oxygen content of the body during surgery of the heart and great vessels.
Golab, H.D. (Hanna)
core  

Modified Glucose-Insulin-Potassium Regimen Provides Cardioprotection With Improved Tissue Perfusion in Patients Undergoing Cardiopulmonary Bypass Surgery [PDF]

open access: yes, 2020
Background Laboratory studies demonstrate glucose-insulin-potassium (GIK) as a potent cardioprotective intervention, but clinical trials have yielded mixed results, likely because of varying formulas and timing of GIK treatment and different clinical ...
Chen, Wensheng   +12 more
core   +1 more source

Genetic variation of TLR4 influences immunoendocrine stress response: an observational study in cardiac surgical patients [PDF]

open access: yes, 2011
Introduction: Systemic inflammation (e.g. following surgery) involves Toll-like receptor (TLR) signaling and leads to an endocrine stress response. This study aims to investigate a possible influence of TLR2 and TLR4 single nucleotide polymorphisms (SNPs)
Boehm, Olaf   +9 more
core   +2 more sources

Understanding the influence of transfusion and blood loss on tranexamic acid concentration in scoliosis surgery with blood loss

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Tranexamic acid (TXA) stabilizes clot formation by inhibiting fibrin degradation and improves postoperative outcomes. However, rare adverse events (e.g., thrombosis, seizures) warrant dose–risk evaluation. This study examines how perioperative blood loss and transfusion practices affect TXA concentrations during paediatric scoliosis surgery ...
Paula Alexandra Sá   +4 more
wiley   +1 more source

Clinical outcomes following surgical intervention for critical congenital heart disease in neonates: a retrospective study in China

open access: yesBMC Pediatrics
Objective This study aims to examine the incidence and clinical outcomes of critical congenital heart disease (CCHD) in neonates in China, with a specific focus on prognostic indicators following surgical intervention.
Xiao-Juan Zhang   +6 more
doaj   +1 more source

Topical use of antifibrinolytic agents reduces postoperative bleeding: a double-blind, prospective, randomized study [PDF]

open access: yes, 2007
Objective: Postoperative bleeding is still one of the most common complications of cardiac surgery. Antifibrinolytic agents successfully reduce bleeding, but there are controversies concerning adverse effects after their systemic use.
Barić, Davor   +7 more
core   +1 more source

Transcatheter Left Ventricular Restoration in Ischemic Heart Failure and Dilated Cardiomyopathy

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Ischemic heart disease is the leading global cause of death and frequently progresses to ischemic heart failure (IHF) after myocardial infarction through adverse left ventricular (LV)remodeling. Surgical LV restoration improves ventricular geometry and function but is limited by invasiveness and inconsistent outcomes.
Muhammad Mohid Haroon   +19 more
wiley   +1 more source

Impact of dexmedetomidine on mortality in critically ill patients with acute kidney injury: a retrospective propensity score matching analysis

open access: yesBMJ Open, 2023
Objectives This study sought to estimate the effect of dexmedetomidine (DEX) administration on mortality in critically ill patients with acute kidney injury (AKI).Design A retrospective cohort study.Setting The study sourced its data from the ...
Peng Gao   +5 more
doaj   +1 more source

TAVR in Male Patients With Large Aortic Valve Annuli: A Propensity‐Matched Analysis of Balloon‐Expandable Versus Self‐Expanding Valves

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Trans‐catheter aortic valve replacement (TAVR) in patients with large annuli poses procedural difficulties and possible complications. Aims We sought to compare the peri‐procedural and long‐term outcomes of patients with large annuli undergoing TAVR with self‐expanding (SEV) versus balloon‐expandable (BEV) valves.
Lior Zornitzki   +12 more
wiley   +1 more source

The organ-protective effects of nitric oxide in adult patients undergoing cardiac surgery with cardiopulmonary bypass: a systematic review and meta-analysis

open access: yesBMC Anesthesiology
Background Postoperative organ dysfunction remains a major challenge in adult cardiac surgery with cardiopulmonary bypass (CPB), frequently involving the kidneys, heart, and lungs.
Jieru Zhang   +10 more
doaj   +1 more source

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