Results 41 to 50 of about 83,107 (337)

Chronic granulomatous disease. Update and review

Revista Alergia México, 2019
Chronic granulomatous disease (CGD) is a primary immunodeficiency syndrome which is characterized by increased susceptibility to severe fungal and bacterial infections.
Itzel López-Hernández, Marcos Suárez-Gutiérrez, Eros Efraín Santos-Chávez, Sara Espinosa, Lizbeth Blancas-Galicia   +4 more
doaj   +1 more source

PTPN22 gene polymorphism in Takayasu's arteritis [PDF]

, 2008
Objective. Takayasu's arteritis (TA) is a chronic, rare granulomatous panarteritis of unknown aetiology involving mainly the aorta and its major branches.
Akar, S., Aksu, K., Ateş, A., Bicakcigil, M., Direskeneli, H., Fresko, I., Inanc, M., Kamali, S., Keser, G., Kiraz, S., Onat, A.M., Sahin, N., Saruhan-Direskeneli, G., Tunç, E., Yücel, E., Çobankara, Veli, Özbalkan, Z., Özer, H., Öztürk, M.A.   +18 more
core   +2 more sources

Glial Fibrillary Acidic Protein Astrocytopathy Based on a Two‐Center Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glial fibrillary acidic protein astrocytopathy (GFAP‐A) is a recently defined nosological form belonging to the class of autoimmune inflammatory disorders affecting the central nervous system (CNS). Here, we report the clinical and MRI characteristics, treatment, and prognosis of a GFAP‐A cohort from two centers in China.
Ti Wu, Hao Zhang, Chao Gao, Qiuhua Yu, Moli Fan, Lin‐Jie Zhang, Haipeng Zhang, Hengri Cong, Yuzhen Wei, Chotima Böttcher, Alexej Verkhratsky, Friedemann Paul, Fu‐Dong Shi, Tian Song   +13 more
wiley   +1 more source

Atypical Presentation of Chronic Granulomatous Disease in a Child

Atti della Accademia Peloritana dei Pericolanti - Classe di Scienze Medico-Biologiche, 2017
Chronic granulomatous disease is a rare, inherited immunodeficiency caused by deletions or mutations in genes that encode subunits of the NADPH oxidase complex. The pattern of chronic granulomatous disease inheritance can be X-linked (about 70% of cases)
Chiara Cuzzupè, Simona Santucci, Elda Pitrolo, Celeste Casto, Irene Viola, Claudio Romano, Mariella Valenzise, Filippo De Luca   +7 more
doaj   +1 more source

Cryptococcus, Pathological observations of five autopsy cases and one biopsy case [PDF]

, 1959
Pathologic, anatomical, and histological findings of 5 autopsy cases and one biopsy case of cryptococcosis have been described. Macroscopically the foci of the lung are grayish white or yellowish white in color and range in size from the small acinous ...
Inohara, Tsuyoshi, Kanamoto, Akihisa, Kuroda, Kiyoshi, Murase, Joji, Ogawa, Katsuo, Uejima, Akira   +5 more
core   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Hybrid Imaging in Head and Neck Sarcoidosis [PDF]

, 2019
To determine the prevalence of head and neck sarcoidosis (HNS) and evaluate the role of hybrid molecular imaging in HNS. Between 2010 and 2018, 222 patients with chronic sarcoidosis and presence of prolonged symptoms of active disease were referred to ...
Artiko, Vera M., Grozdic Milojevic, Isidora, Saponjski, Jelena, Sobic-Saranovic, Dragana, Tadic, Marijana   +4 more
core   +1 more source

Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives

Advanced Science, EarlyView.
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu, Yang Liu, Jian Zhou, Hongli Lai, Hongxia Ruan, Dongsheng Wu, Shun Zhu, Xudong Zhou, Wananqi Ma, Yuchen Huang, Shuting Lei, Han Luo, Jie Chen, Binwu Ying   +13 more
wiley   +1 more source

BCG‐Derived Outer Membrane Vesicles Induce TLR2‐Dependent Trained Immunity to Protect Against Polymicrobial Sepsis

Advanced Science, EarlyView.
B‐OMVs, nanoscale vesicles derived from BCG, are identified as effective and safe inducers of trained immunity that protect against sepsis. Through TLR2‐mediated metabolic and epigenetic reprogramming of hematopoietic stem cells, B‐OMVs enhance inflammatory response and phagocytic activity.
Yuan Gong, Wenyan Hao, Lingqi Xu, Yingyi Yang, Zhenzhen Dong, Peng Pan, Zhenjiang Bai, Jie Huang, Kaidi Yang, Zhu Jin, Rui Kang, Qiang Shan, Jiang huai Wang, Zijian Zhou, Daolin Tang, Jian Wang, Huiting Zhou   +16 more
wiley   +1 more source

Chronic granulomatous disease

Indian Journal of Dermatology, Venereology and Leprology, 2005
A 2(1/2)-year-old child presented with multiple discrete granulomatous lesions on the face and flexural regions since the age of 2 months along with lymphadenopathy. The patient also had recurrent bouts of pyodermas and respiratory tract infections.
S Suprakasan, Prasanna K. Moorthy, K. Preethi, Sabeena Jayapalan, Pradeep S Nair   +4 more
openaire   +3 more sources