Results 41 to 50 of about 318,207 (300)
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Abelian combinatorial gauge symmetry
SciPost Physics CoreCombinatorial gauge symmetry is a principle that allows us to construct lattice gauge theories with two key and distinguishing properties: a) only one- and two-body interactions are needed; and b) the symmetry is exact rather than emergent in an ...
Hongji Yu, Dmitry Green, Andrei E. Ruckenstein, Claudio Chamon
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Comments on QCD3 and anomalies with fundamental and adjoint matter
Journal of High Energy Physics, 2022 ’t Hooft anomaly matching is powerful for constraining the low energy phases of gauge theories. In 3d one common anomaly is the parity anomaly in a T-symmetric theory where one cannot gauge the global symmetry group without breaking the time-reversal ...
Nakarin Lohitsiri, Tin Sulejmanpasic
doaj +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Non-invertible global symmetries and completeness of the spectrum
Journal of High Energy Physics, 2021 It is widely believed that consistent theories of quantum gravity satisfy two basic kinematic constraints: they are free from any global symmetry, and they contain a complete spectrum of gauge charges.
Ben Heidenreich +5 more
doaj +1 more source
Symmetry and Z_2-Orbifolding Approach in Five-dimensional Lattice Gauge Theory
, 2010 In a lattice gauge-Higgs unification scenario using a Z_2-orbifolded extra-dimension, we find a new global symmetry in a case of SU(2) bulk gauge symmetry.
Ishiyama, K. +3 more
core +1 more source
FEBS Open Bio, EarlyView.This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
Automatic Peccei–Quinn symmetry
European Physical Journal C: Particles and Fields, 2019 We present a dynamical (composite) axion model where the Peccei–Quinn (PQ) symmetry arises automatically as a consequence of chirality and gauge symmetry. The Standard Model is simply extended by a confining and chiral SU(5) gauge symmetry.
M. B. Gavela +3 more
doaj +1 more source