Results 41 to 50 of about 29,293 (218)

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

Neisseria meningitidis Serogroup X ST-5799 (ST-22 complex) in Turkey: A unique pediatric case

open access: yesHuman Vaccines & Immunotherapeutics, 2018
Although outbreaks of Neisseria meningitidis serogroup X occured in a couple of African countries, a limited number of serogroup X meningococcal cases were reported in America and Europe as well as Turkey.
Gönül Tanır   +8 more
doaj   +1 more source

Genomics of Neisseria meningitidis

open access: yesInternational Journal of Medical Microbiology, 2001
An important feature of disease caused by Neisseria meningitidis is the propensity to invade the meninges. Much progress has been made in our understanding of how this pathogen circumvents the physical properties of this cellular barrier. This review will address the new possibilities offered by the recent availability of meningococcal genome sequences.
openaire   +2 more sources

Heparin‐Binding Protein in Cerebrospinal Fluid as a Biomarker for Bacterial Meningitis: A Study of Diagnostic Accuracy

open access: yesAnnals of Neurology, EarlyView.
Objective We aimed to evaluate the diagnostic accuracy of heparin‐binding protein (HBP) in cerebrospinal fluid for the diagnosis of bacterial meningitis in patients with a suspected central nervous system infection. Methods This prospective multicenter cohort study determined the diagnostic accuracy of HBP in cerebrospinal fluid (CSF) for bacterial ...
Sabine E. Olie   +6 more
wiley   +1 more source

Conservation of Meningococcal Antigens in the Genus Neisseria

open access: yesmBio, 2013
Neisseria meningitidis, one of the major causes of bacterial meningitis and sepsis, is a member of the genus Neisseria, which includes species that colonize the mucosae of many animals.
Alessandro Muzzi   +4 more
doaj   +1 more source

A systematic review of the diagnostic accuracy of Loop-mediated-isothermal AMPlification (LAMP) in the diagnosis of invasive meningococcal disease in children

open access: yesBMC Pediatrics, 2019
Background The early recognition of meningococcal disease in children is vital. During the prodrome however, meningococcal infection presents similarly to many self-limiting viral infections. This mandates a cautious approach with many children receiving
Thomas Waterfield   +4 more
doaj   +1 more source

Variabilidad de las meningoencefalitis bacterianas en el Hospital Pediátrico "Pepe Portilla" Variability of the bacterial meningoencephalitis at "Pepe Portilla" Paediatric Hospital

open access: yesRevista de Ciencias Médicas de Pinar del Río, 2009
Se realizó un estudio retrospectivo y prospectivo longitudinal de las Meningoencefalitis Bacterianas diagnosticadas en el Hospital Pediátrico "Pepe Portilla" en el año 2006 y 2007, con el objetivo de determinar los gérmenes que han aislado en dicha ...
Maydelin Fernández González   +3 more
doaj  

Recent Advancements in Microfluidic Biosensors for Clinical Applications

open access: yesiLABMED, EarlyView.
The combination of low‐consumption microfluidic chips and high‐sensitivity biosensors enables rapid and accurate detection of complex target analytes. This integrated system holds significant potential for applications in disease diagnosis, health monitoring, and treatment management.
Haiyan Wang, Wenjuan Wu
wiley   +1 more source

Species-specificity of the BamA component of the bacterial outer membrane protein-assembly machinery. [PDF]

open access: yesPLoS ONE, 2013
The BamA protein is the key component of the Bam complex, the assembly machinery for outer membrane proteins (OMP) in gram-negative bacteria. We previously demonstrated that BamA recognizes its OMP substrates in a species-specific manner in vitro.
Elena B Volokhina   +6 more
doaj   +1 more source

Early detection of cerebrospinal fluid/serum glucose ratio: A promising value for mortality prognosis in patients with acute bacterial meningitis

open access: yesJournal of General and Family Medicine, EarlyView.
This study revealed that a glucometer‐based measurement significantly improved the turnaround time required for CSF/serum glucose ratio measurement compared to conventional laboratory tests, which could be considered a reliable aid to the mortality prognosis.
Nasrin Khodashenas   +3 more
wiley   +1 more source

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