Mining of Leaf Rust Resistance Genes Content in Egyptian Bread Wheat Collection
Plants, 2021 Wheat is a major nutritional cereal crop that has economic and strategic value worldwide. The sustainability of this extraordinary crop is facing critical challenges globally, particularly leaf rust disease, which causes endless problems for wheat ...
Mohamed A. M. Atia +5 more
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Mfold web server for nucleic acid folding and hybridization prediction
Nucleic Acids Res., 2003 The abbreviated name, 'mfold web server', describes a number of closely related software applications available on the World Wide Web (WWW) for the prediction of the secondary structure of single stranded nucleic acids.
M. Zuker
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Nucleic acid–protein interfaces studied by MAS solid-state NMR spectroscopy
Journal of Structural Biology: X, 2022 Solid-state NMR (ssNMR) has become a well-established technique to study large and insoluble protein assemblies. However, its application to nucleic acid–protein complexes has remained scarce, mainly due to the challenges presented by overlapping nucleic
Philipp Innig Aguion +2 more
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Structure and Composition Define Immunorecognition of Nucleic Acid Nanoparticles.
Nano letters (Print), 2018 Nucleic acid nanoparticles (NANPs) have evolved as a new class of therapeutics with the potential to detect and treat diseases. Despite tremendous advancements in NANP development, their immunotoxicity, one of the major impediments in clinical ...
Enping Hong +5 more
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Splitting aptamers and nucleic acid enzymes for the development of advanced biosensors
Nucleic Acids Research, 2020 In analogy to split-protein systems, which rely on the appropriate fragmentation of protein domains, split aptamers made of two or more short nucleic acid strands have emerged as novel tools in biosensor set-ups.
Mégane Debiais +3 more
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Lipid-Nucleic Acid Supramolecular Complexes: Lipoplex Structure and the Kinetics of Formation
AIMS Biophysics, 2015 The need for synthetic gene therapy or gene silencing vehicles that can insert therapeutic nucleic acids (DNA or siRNA) into cells (so-called transfection) has focused interest on lipid-nucleic acid assemblies (lipoplexes).
Nily Dan
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G4IPDB: A database for G-quadruplex structure forming nucleic acid interacting proteins
Scientific Reports, 2016 Nucleic acid G-quadruplex structure (G4) Interacting Proteins DataBase (G4IPDB) is an important database that contains detailed information about proteins interacting with nucleic acids that forms G-quadruplex structures.
S. Mishra +3 more
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Dioxaphosphorinane-Constrained Nucleic Acid Dinucleotides as Tools for Structural Tuning of Nucleic Acids [PDF]
Journal of Nucleic Acids, 2012 We describe a rational approach devoted to modulate the sugar-phosphate backbone geometry of nucleic acids. Constraints were generated by connecting one oxygen of the phosphate group to a carbon of the sugar moiety. The so-called dioxaphosphorinane rings were introduced at key positions along the sugar-phosphate backbone allowing the control of the six-
Catana, Dan-Andrei +5 more
openaire +5 more sources
Dissecting Functional Biological Interactions Using Modular RNA Nanoparticles
Molecules, 2022 Nucleic acid nanoparticles (NANPs) are an exciting and innovative technology in the context of both basic and biomedical research. Made of DNA, RNA, or their chemical analogs, NANPs are programmed for carrying out specific functions within human cells ...
Kaitlin Klotz +2 more
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Sharing and archiving nucleic acid structure mapping data.
RNA: A publication of the RNA Society, 2011 Nucleic acids are particularly amenable to structural characterization using chemical and enzymatic probes. Each individual structure mapping experiment reveals specific information about the structure and/or dynamics of the nucleic acid.
P. Rocca-Serra +16 more
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