Results 41 to 50 of about 23,867 (162)

The insertion of Neomycin cassette impairs maternal and social behaviors in Arc/Arg3.1 knock-out mice [PDF]

arXiv
The Neomycin resistance cassette (Neo+) is commonly inserted in the genome of mice to generate knock-out (KO) models. The effect of gene deletion on social behaviors in mice is controversial between studies using different Neo+ and Neo-mouse lines, particularly Arc/Arg3.1 KO lines.
arxiv  

Diagnosis and successful treatment of open pyometra in a wild European brown hare (Lepus europaeus)

Veterinary Record Case Reports, EarlyView.
Abstract This case report describes an open pyometra in a wild adult female hare (Lepus europaeus) that was rescued in the Umbria countryside (Italy) during mid‐January. The clinical signs observed included anorexia and a mucopurulent to haemorrhagic discharge from the vulva.
Claudia Massone, Oriana Cianca, Isabella Costantino, Daniele Marini, Domenico Caivano   +4 more
wiley   +1 more source

Towards the convergent therapeutic potential of G protein‐coupled receptors in autism spectrum disorders

British Journal of Pharmacology, EarlyView., 2023
Abstract Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two core symptoms: deficits in social interaction and communication, and stereotyped behaviours. G protein‐coupled receptors (GPCRs) are the largest family of cell‐surface receptors that transduce extracellular signals to convergent intracellular signalling ...
Anil Annamneedi, Caroline Gora, Ana Dudas, Xavier Leray, Véronique Bozon, Pascale Crépieux, Lucie P. Pellissier   +6 more
wiley   +1 more source

Factors Influencing Pregnant Women's Participation in Randomised Clinical Trials in India: A Qualitative Study

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 132, Issue 6, Page 772-781, May 2025.
ABSTRACT Objective To explore factors affecting participation of pregnant women in randomised clinical trials in Belagavi, Karnataka, India. Design A qualitative study using semi‐structured in‐depth interviews and focus group discussions as data collection methods.
Mridula Shankar, Umesh Charantimath, Ashwini Dandappanavar, Alya Hazfiarini, Yeshita V. Pujar, Manjunath S. Somannavar, Sara Rushwan, Joshua P. Vogel, A. Metin Gülmezoglu, Shivaprasad S. Goudar, Meghan A. Bohren   +10 more
wiley   +1 more source

Gαq signalling from endosomes: A new conundrum

British Journal of Pharmacology, EarlyView., 2023
Abstract G‐protein‐coupled receptors (GPCRs) constitute the largest family of membrane receptors, and are involved in the transmission of a variety of extracellular stimuli such as hormones, neurotransmitters, light and odorants into intracellular responses.
Carole Daly, Bianca Plouffe
wiley   +1 more source

Intrauterine Contraction Monitoring in Chorioamnionitis: A Secondary, Blinded Analysis of a Randomised Controlled Trial Cohort

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 132, Issue 6, Page 795-804, May 2025.
ABSTRACT Objective To study the effects of chorioamnionitis on uterine activity and to investigate associations between external and intrauterine monitoring methods and neonatal outcomes. Design Secondary analysis of a randomised controlled trial cohort. Setting Two labour wards, in a university tertiary hospital and a central hospital.
Milla Juhantalo, Tuija Hautakangas, Outi Palomäki, Jukka Uotila   +3 more
wiley   +1 more source

Ectopic and molar pregnancies in Brazil: A secondary analysis of the WHO multi‐country survey on abortion

International Journal of Gynecology &Obstetrics, EarlyView.
Luís Henrique Leão, Camila Ayume Amano Cavalari, Luiz Francisco Baccaro   +2 more
wiley   +1 more source

Risk Prediction Models for Stress Urinary Incontinence in Pregnant and Postpartum Women: A Systematic Review and Critical Appraisal

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 132, Issue 7, Page 880-891, June 2025.
ABSTRACT Background Many studies have developed or validated prediction models to estimate the risk of stress urinary incontinence (SUI) in pregnant and postpartum women, but the quality of the model development and model applicability remains unknown. Objectives To systematically review and critically evaluate currently available prediction models for
Yuqing Hou, Suwen Feng, Baoqin Tong, Shuping Lu, Hongyan Wang   +4 more
wiley   +1 more source

Propranolol and Oxytocin‐Induced Contractility in Gravid Human Myometrium: An Ex Vivo Laboratory Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To determine the effect of propranolol on myometrial contractions induced by low dose and high dose oxytocin. Design Prospective ex vivo laboratory study. Setting Mount Sinai Hospital, Toronto. Population Full‐term parturients who underwent elective caesarean deliveries (CD).
Mrinalini Balki, Lauren M. Miller, Jayalakshmi Caliaperumal, Stella Wang, Ella Huszti, John C. Kingdom   +5 more
wiley   +1 more source

Progesterone Luteal Support in Natural Cycles for Unexplained Infertility: A Randomised Controlled Trial (The PiNC Trial)

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To compare the effect of luteal‐phase progesterone supplementation in natural cycles to expectant management on live birth rates in women with unexplained infertility (UI). Design An open‐label, parallel‐arm, single‐centre randomised controlled trial. Setting One tertiary NHS‐funded fertility unit.
Claudia Raperport, Elpiniki Chronopoulou, Aviva Petrie, Roy Homburg, Elizabeth Timlick, Sheetal Barhate, Kristina Sackett, Priya Bhide   +7 more
wiley   +1 more source