Results 41 to 50 of about 336,402 (275)

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Impact of pneumococcal conjugate vaccination: a retrospective study of hospitalization for pneumonia in North-East Italy [PDF]

, 2016
Introduction. Pneumonia remains a common reason for hospitalizing infants and the elderly worldwide, and streptococcal infection is often responsible. The aim of this study was to assess the burden of pneumonia in a large general population. Methods. All
Baldo, Vincenzo, Baldovin, Tatjana, Bertoncello, Chiara, Buja, Alessandra, Clagnan, E, Cocchio, Silvia, Del Zotto, S, Furlan, Patrizia, Gallo, T, Saia, Mario   +9 more
core   +1 more source

Point-of-care measurement of blood lactate in children admitted with febrile illness to an African District Hospital. [PDF]

, 2011
BACKGROUND: Lactic acidosis is a consistent predictor of mortality owing to severe infectious disease, but its detection in low-income settings is limited to the clinical sign of "deep breathing" because of the lack of accessible technology for its ...
Acierno, B. Amos, B. Nadjm, Day, English, English, English, F. Muro, G. Mtove, Gore, H. Reyburn, I. C. E. Hendriksen, J. Todd, Kahigwa, Krishna, Krishna, Maitland, Marsh, Marsh, Molyneux, Nadjm, Reyburn, Taylor   +22 more
core   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Expression and significance of serum vitamin D and LL-37 levels in infants with bacterial pneumonia

Frontiers in Pediatrics, 2022
ObjectiveTo investigate the significance of vitamin D and human antimicrobial peptide LL-37 in the occurrence and development of bacterial pneumonia in infants.MethodsFrom January 2021 to January 2022, 80 infants with bacterial pneumonia were selected ...
Shaojie Zhao, Shaojie Zhao, Yixiu He, Menglan Pan, Bingzhang Chen, Siqi Zhang, Yufeng Zhang, Yafei Zhu   +7 more
doaj   +1 more source

Demographic characteristics and opportunistic diseases associated with attrition during preparation for antiretroviral therapy in primary health centres in Kibera, Kenya. [PDF]

, 2011
Using routine data from HIV-positive adult patients eligible for antiretroviral therapy (ART), we report on routinely collected demographic characteristics and opportunistic diseases associated with pre-ART attrition (deaths and loss to follow-up). Among
Amuron, Anglaret, Boehme, Braitstein, Etard, Fox, Gilks, Gilks, Grant, Ingle, Ingle, Janoof, Jones, Larson, Lawn, Lawn, Lucas, Peters, Scott, Van Griensven, Zachariah   +20 more
core   +2 more sources

Will Memantine Exacerbate Seizures in People With Epilepsy? A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate whether add‐on memantine would exacerbate seizures in people with epilepsy. Methods This was a prospective cohort study. People with epilepsy diagnosed with cognitive impairment were consecutively invited. Those who agreed were followed up for at least 24 weeks.
Peiyu Wang, Lu Lu, Hui Gao, Qi Zhang, Jing Xiao, Josemir W. Sander, Weixi Xiong, Dong Zhou   +7 more
wiley   +1 more source

Systemic infections after acute stroke [PDF]

, 2008
After an acute stroke, systemic infection can complicate the recovery process and lead to a worse clinical outcome, including a higher risk of mortality.
Damian Jenkinson, Englyst, Hamidon, Joseph Kwan, Kammersgaard, Kwan, Mike Vassallo, Nicola Englyst, Niel-Weise, Oconnor, V Hugh Perry, Werner   +11 more
core   +1 more source

Life‐Threatening Bradycardia in Anti‐NMDA‐Receptor Encephalitis and a Novel Use for Permanent Pacing

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Pediatric anti‐NMDA receptor encephalitis (pNMDARE) is an autoantibody‐mediated disorder that can cause severe autonomic dysfunction, including symptomatic bradycardia and asystole. Dysautonomia can last for years, making it very challenging to manage.
Sarah Tucker, Abhijit Das, Andres Jimenez, Areeba Basit, Yike Jiang, Emily A. Smitherman, Heather Van Mater, Taylor Howard, Alexander J. Sandweiss, Kristen S. Fisher   +9 more
wiley   +1 more source

Accuracy of the diagnosis of pneumonia in Canadian pediatric emergency departments: A prospective cohort study.

PLoS ONE
BackgroundThe diagnosis of pediatric pneumonia and determination of the likely pathogen are complicated as the clinical picture overlaps with other respiratory illnesses, interpretation of radiographs is subjective, and laboratory results are rarely ...
Joan L Robinson, James D Kellner, Jennifer Crotts, Gabino Travassos, Guanmin Chen, Valerie G Kirk, Martin Pusic, Martin Reed, Sarah Reid, Michael Weinstein, Ravi Bhargava, Maala Bhatt, Kathy Boutis, Sarah Curtis, Serge Gouin, Tim Lynch, Richard van Wylick, David W Johnson   +17 more
doaj   +1 more source