Results 1 to 10 of about 29,910 (137)

Assessment of an Antibody-in-Lymphocyte Supernatant Assay for the Etiological Diagnosis of Pneumococcal Pneumonia in Children

Frontiers in Cellular and Infection Microbiology, 2020
New diagnostic tests for the etiology of childhood pneumonia are needed. We evaluated the antibody-in-lymphocyte supernatant (ALS) assay to detect immunoglobulin (Ig) G secretion from ex vivo peripheral blood mononuclear cell (PBMC) culture, as a ...
Michael J. Carter, Michael J. Carter, Michael J. Carter, Michael J. Carter, Michael J. Carter, Pallavi Gurung, Claire Jones, Claire Jones, Shristy Rajkarnikar, Rama Kandasamy, Rama Kandasamy, Meeru Gurung, Stephen Thorson, Madhav C. Gautam, Krishna G. Prajapati, Bibek Khadka, Anju Maharjan, Julian C. Knight, David R. Murdoch, Thomas C. Darton, Thomas C. Darton, Thomas C. Darton, Merryn Voysey, Merryn Voysey, Brian Wahl, Katherine L. O'Brien, Sarah Kelly, Sarah Kelly, Imran Ansari, Ganesh Shah, Nina Ekström, Merit Melin, Andrew J. Pollard, Andrew J. Pollard, Dominic F. Kelly, Dominic F. Kelly, Shrijana Shrestha   +36 more
doaj   +1 more source

Epidemiology of Pneumococcal Pneumonia in Louisville, Kentucky, and Its Estimated Burden of Disease in the United States

Microorganisms, 2023
Streptococcus pneumoniae remains a primary pathogen in hospitalized patients with community-acquired pneumonia (CAP). The objective of this study was to define the epidemiology of pneumococcal pneumonia in Louisville, Kentucky, and to estimate the burden
Julio Ramirez, Stephen Furmanek, Thomas R. Chandler, Timothy Wiemken, Paula Peyrani, Forest Arnold, William Mattingly, Ashley Wilde, Jose Bordon, Rafael Fernandez-Botran, Ruth Carrico, Rodrigo Cavallazzi, The University of Louisville Pneumonia Study Group   +12 more
doaj   +1 more source

The potential role of pneumococcal conjugate vaccine in reducing acute respiratory inflammation in community-acquired pneumococcal pneumonia

Journal of Biomedical Science, 2020
Background Pneumococcal conjugate vaccine (PCV) reduces both invasive pneumococcal disease (IPD) and other pneumococcal infections worldwide. We investigated the impact of stepwise implementation of childhood PCV programs on the prevalence of ...
Ching-Fen Shen, Shih-Min Wang, Hsin Chi, Yi-Chuan Huang, Li-Min Huang, Yhu-Chering Huang, Hsiao-Chuan Lin, Yu-Huai Ho, Chao A. Hsiung, Ching-Chuan Liu, Taiwan Pediatric Infectious Disease Alliance   +10 more
doaj   +1 more source

Clinical and Microbiological Factors Associated with High Nasopharyngeal Pneumococcal Density in Patients with Pneumococcal Pneumonia. [PDF]

PLoS ONE, 2015
We aimed to study if certain clinical and/or microbiological factors are associated with a high nasopharyngeal (NP) density of Streptococcus pneumoniae in pneumococcal pneumonia.
Helena Alpkvist, Simon Athlin, Pontus Nauclér, Björn Herrmann, Guma Abdeldaim, Hans-Christian Slotved, Jonas Hedlund, Kristoffer Strålin   +7 more
doaj   +1 more source

Use of procalcitonin and C-reactive protein to evaluate vaccine efficacy against pneumonia. [PDF]

PLoS Medicine, 2005
Pneumonia remains the leading cause of death in young children. The poor specificity of chest radiographs (CXRs) to diagnose pneumococcal pneumonia may underestimate the efficacy of pneumococcal conjugate vaccine in preventing pneumococcal pneumonia.The ...
Shabir A Madhi, Jayvant R Heera, Locadiah Kuwanda, Keith P Klugman   +3 more
doaj   +1 more source

Incidence of Hospitalized Pneumococcal Pneumonia among Adults in Guatemala, 2008-2012. [PDF]

PLoS ONE, 2015
Streptococcus pneumoniae is a leading cause of pneumonia worldwide. However, the burden of pneumococcal pneumonia among adults in low- and middle-income countries is not well described.Data from 2008-2012 was analyzed from two surveillance sites in ...
Carmen Lucía Contreras, Jennifer R Verani, María Renee Lopez, Antonio Paredes, Chris Bernart, Fabiola Moscoso, Aleida Roldan, Wences Arvelo, Kim A Lindblade, John P McCracken   +9 more
doaj   +1 more source

A Retrospective Analysis to Estimate the Burden of Invasive Pneumococcal Disease and Non-Invasive Pneumonia in Children <15 Years of Age in the Veneto Region, Italy

Children, 2022
Despite advances in preventative interventions, invasive pneumococcal disease and pneumonia cause significant morbidity and mortality in children. We studied the annual incidence of pneumococcal-specific and syndromic invasive disease and non-invasive ...
Elisa Barbieri, Gloria Porcu, Tianyan Hu, Tanaz Petigara, Francesca Senese, Gian Marco Prandi, Antonio Scamarcia, Luigi Cantarutti, Anna Cantarutti, Carlo Giaquinto   +9 more
doaj   +1 more source

Invasive pneumococcal disease, pneumococcal pneumonia and all-cause pneumonia in Hong Kong during the COVID-19 pandemic compared with the preceding 5 years: a retrospective observational study

BMJ Open, 2021
Objectives To compare the incidence and severity of invasive pneumococcal diseases (IPDs), pneumococcal pneumonia and all-cause pneumonia during the COVID-19 pandemic period with universal masking and social distancing with that of previous 5 years ...
Pak-leung Ho, King-Pui Florence Chan, Ting-Fung Ma, Mary Sau-Man Ip   +3 more
doaj   +1 more source

Response to Shami et al. ‘Evaluating the cost-effectiveness of a sequential pneumococcal vaccination compared to single dose vaccination strategy for adults in Hong Kong’ (Hum Vacc Immunother 2020)

Human Vaccines & Immunotherapeutics, 2021
The recently published article by Shami et al. describes a cost-effectiveness analysis of sequential pneumococcal vaccination with 13-valent pneumococcal conjugate vaccine (PCV13) followed by 23-valent pneumococcal polysaccharide vaccine (PPSV23 ...
Ulrike K. Buchwald, Temitope Folaranmi, Thomas Weiss   +2 more
doaj   +1 more source

Influence of Older Age and Other Risk Factors on Pneumonia Hospitalization in Switzerland in the Pneumococcal Vaccine Era

Frontiers in Medicine, 2019
Background: Pneumococcal pneumonia is a disease of the extremes of age. However, as other traditional risk factors for pneumococcal pneumonia also increase with older age, it is unclear if older age itself should be an indication for pneumococcal ...
Werner C. Albrich, Frank Rassouli, Frederike Waldeck, Christoph Berger, Florent Baty   +4 more
doaj   +1 more source