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Pneumococcal pneumonia [PDF]

Thorax, 2019
Pneumococcal conjugate vaccines (PCV) were first licensed in 2000 and have been introduced into national immunisation programme in more than 145 countries.
David Goldblatt, Elizabeth Miller
openaire   +5 more sources

Invasive pneumococcal disease, pneumococcal pneumonia and all-cause pneumonia in Hong Kong during the COVID-19 pandemic compared with the preceding 5 years: a retrospective observational study

BMJ Open, 2021
Objectives To compare the incidence and severity of invasive pneumococcal diseases (IPDs), pneumococcal pneumonia and all-cause pneumonia during the COVID-19 pandemic period with universal masking and social distancing with that of previous 5 years ...
Pak-leung Ho, King-Pui Florence Chan, Ting-Fung Ma, Mary Sau-Man Ip   +3 more
doaj   +2 more sources

Burden of Severe Pneumonia, Pneumococcal Pneumonia and Pneumonia Deaths in Indian States: Modelling Based Estimates.

PLoS ONE, 2015
The burden of severe pneumonia in terms of morbidity and mortality is unknown in India especially at sub-national level. In this context, we aimed to estimate the number of severe pneumonia episodes, pneumococcal pneumonia episodes and pneumonia deaths ...
Habib Farooqui, Mark Jit, David L Heymann, Sanjay Zodpey   +3 more
doaj   +2 more sources

Influence of Older Age and Other Risk Factors on Pneumonia Hospitalization in Switzerland in the Pneumococcal Vaccine Era

Frontiers in Medicine, 2019
Background: Pneumococcal pneumonia is a disease of the extremes of age. However, as other traditional risk factors for pneumococcal pneumonia also increase with older age, it is unclear if older age itself should be an indication for pneumococcal ...
Werner C. Albrich, Frank Rassouli, Frederike Waldeck, Christoph Berger, Florent Baty   +4 more
doaj   +2 more sources

Neutrophil Recruitment in Pneumococcal Pneumonia

Frontiers in Cellular and Infection Microbiology, 2022
Streptococcus pneumoniae (Spn) is the primary agent of community-acquired pneumonia. Neutrophils are innate immune cells that are essential for bacterial clearance during pneumococcal pneumonia but can also do harm to host tissue. Neutrophil migration in
Catherine S. Palmer, Jacqueline M. Kimmey   +1 more
doaj   +2 more sources

Btk inhibitor ibrutinib reduces inflammatory myeloid cell responses in the lung during murine pneumococcal pneumonia

Molecular Medicine, 2019
Background Streptococcus pneumoniae is a major causative agent in community-acquired pneumonia and sepsis. Overwhelming lung inflammation during pneumococcal pneumonia may hamper lung function.
Alexander P. de Porto, Zhe Liu, Regina de Beer, Sandrine Florquin, Onno J. de Boer, Rudi W. Hendriks, Tom van der Poll, Alex F. de Vos   +7 more
doaj   +2 more sources

Systematic review on the impact of the pneumococcal conjugate vaccine ten valent (PCV10) or thirteen valent (PCV13) on all-cause, radiologically confirmed and severe pneumonia hospitalisation rates and pneumonia mortality in children 0-9 years old

Journal of Global Health, 2023
Background There is an ongoing need to assess the impact of pneumococcal conjugate vaccines (PCVs) to guide the use of these potentially valuable but under-utilized vaccines against pneumonia, which is one of the most common causes of post-neonatal ...
R. Reyburn, Anthea Tsatsaronis, Claire von Mollendorf, Kim Mulholland, Fiona M. Russell, Trevor Hamish Steve Amy Amanda Claire Kim Fiona Maeve San Duke Graham Graham Gray Gwee von Mollendorf Mulhol, T. Duke, H. Graham, Steve Graham, Amy Z Gray, A. Gwee, Claire von Mollendorf, Kim Mulholland, Fiona M. Russell, Maeve Hume-Nixon, Saniya Kazi, Priya M Kevat, Eleanor Neal, C. Nguyen, A. Quach, R. Reyburn, K. Ryan, P. Walker, C. Wilkes, P. Chua, Yasir Bin Nisar, J. Simon, W. Were   +27 more
semanticscholar   +1 more source

Incidence and Estimated Vaccine Effectiveness Against Hospitalizations for All-Cause Pneumonia Among Older US Adults Who Were Vaccinated and Not Vaccinated With 13-Valent Pneumococcal Conjugate Vaccine

JAMA Network Open, 2022
This cohort study estimates the association between vaccination with 13-valent pneumococcal conjugate vaccine and hospitalizations for all-cause pneumonia and lower respiratory tract infection among older adults in a large health care system in ...
Amber Hsiao, John R Hansen, J. Timbol, Ned Lewis, R. Isturiz, R. Alexander-Parrish, J. McLaughlin, B. Gessner, Nicola P Klein   +8 more
semanticscholar   +1 more source

Recruitment and training of alveolar macrophages after pneumococcal pneumonia

JCI Insight, 2022
Recovery from pneumococcal pneumonia remodels the pool of alveolar macrophages so that they exhibit new surface marker profiles, transcriptomes, metabolomes, and responses to infection.
E. Arafa, A. Shenoy, K. Barker, N. Etesami, I. Martin, C. Lyon, De Ana, E. Na, C. Odom, Wesley N. Goltry, F. Korkmaz, A. Wooten, Anna C. Belkina, A. Guillon, E. Forsberg, Matthew R. Jones, L. Quinton, J. Mizgerd, C. L. D. Ana   +18 more
semanticscholar   +1 more source

PCV13 Vaccination of Adults against Pneumococcal Disease: What We Have Learned from the Community-Acquired Pneumonia Immunization Trial in Adults (CAPiTA)

Microorganisms, 2022
The Community-Acquired Pneumonia immunization Trial in Adults (CAPiTA) evaluated older adult pneumococcal vaccination and was one of the largest vaccine clinical trials ever conducted.
C. Theilacker, M. Fletcher, L. Jodar, B. Gessner   +3 more
semanticscholar   +1 more source