Results 11 to 20 of about 417,620 (216)
Frontiers in Cellular and Infection Microbiology, 2020 New diagnostic tests for the etiology of childhood pneumonia are needed. We evaluated the antibody-in-lymphocyte supernatant (ALS) assay to detect immunoglobulin (Ig) G secretion from ex vivo peripheral blood mononuclear cell (PBMC) culture, as a ...
Michael J. Carter +36 more
doaj +1 more source
The Role of Neutrophils and Neutrophil Elastase in Pneumococcal Pneumonia
Frontiers in Cellular and Infection Microbiology, 2021 Streptococcus pneumoniae, also known as pneumococcus, is a Gram-positive diplococcus and a major human pathogen. This bacterium is a leading cause of bacterial pneumonia, otitis media, meningitis, and septicemia, and is a major cause of morbidity and ...
H. Domon, Y. Terao
semanticscholar +1 more source
Microorganisms, 2023 Streptococcus pneumoniae remains a primary pathogen in hospitalized patients with community-acquired pneumonia (CAP). The objective of this study was to define the epidemiology of pneumococcal pneumonia in Louisville, Kentucky, and to estimate the burden
Julio Ramirez +12 more
doaj +1 more source
Non-invasive pneumococcal pneumonia due to vaccine serotypes: A systematic review and meta-analysis
EClinicalMedicine, 2021 Summary Background Non-invasive pneumococcal pneumonia causes significant morbidity and mortality in older adults. Understanding pneumococcal sero-epidemiology in adults ≥50 years is necessary to inform vaccination policies and the updating of ...
L. Lansbury +4 more
semanticscholar +1 more source
Journal of Biomedical Science, 2020 Background Pneumococcal conjugate vaccine (PCV) reduces both invasive pneumococcal disease (IPD) and other pneumococcal infections worldwide. We investigated the impact of stepwise implementation of childhood PCV programs on the prevalence of ...
Ching-Fen Shen +10 more
doaj +1 more source
Clinical and Microbiological Factors Associated with High Nasopharyngeal Pneumococcal Density in Patients with Pneumococcal Pneumonia. [PDF]
PLoS ONE, 2015 We aimed to study if certain clinical and/or microbiological factors are associated with a high nasopharyngeal (NP) density of Streptococcus pneumoniae in pneumococcal pneumonia.
Helena Alpkvist +7 more
doaj +1 more source
A longitudinal analysis of pneumococcal vaccine serotypes in pneumonia patients in Germany
European Respiratory Journal, 2021 Pneumococcal infections are globally the most frequent vaccine-preventable cause of death [1], and community-acquired pneumonia (CAP) caused by Streptococcus pneumoniae is the main burden of pneumococcal disease in the elderly [2].
C. Bahrs +9 more
semanticscholar +1 more source
Use of procalcitonin and C-reactive protein to evaluate vaccine efficacy against pneumonia. [PDF]
PLoS Medicine, 2005 Pneumonia remains the leading cause of death in young children. The poor specificity of chest radiographs (CXRs) to diagnose pneumococcal pneumonia may underestimate the efficacy of pneumococcal conjugate vaccine in preventing pneumococcal pneumonia.The ...
Shabir A Madhi +3 more
doaj +1 more source
Incidence of Hospitalized Pneumococcal Pneumonia among Adults in Guatemala, 2008-2012. [PDF]
PLoS ONE, 2015 Streptococcus pneumoniae is a leading cause of pneumonia worldwide. However, the burden of pneumococcal pneumonia among adults in low- and middle-income countries is not well described.Data from 2008-2012 was analyzed from two surveillance sites in ...
Carmen Lucía Contreras +9 more
doaj +1 more source
Children, 2022 Despite advances in preventative interventions, invasive pneumococcal disease and pneumonia cause significant morbidity and mortality in children. We studied the annual incidence of pneumococcal-specific and syndromic invasive disease and non-invasive ...
Elisa Barbieri +9 more
doaj +1 more source