Burden of Severe Pneumonia, Pneumococcal Pneumonia and Pneumonia Deaths in Indian States: Modelling Based Estimates. [PDF]
, 2015 The burden of severe pneumonia in terms of morbidity and mortality is unknown in India especially at sub-national level. In this context, we aimed to estimate the number of severe pneumonia episodes, pneumococcal pneumonia episodes and pneumonia deaths ...
Farooqui, Habib +3 more
core +15 more sources
Insights into pneumococcal pneumonia using lung aspirates and nasopharyngeal swabs collected from pneumonia patients in The Gambia. [PDF]
, 2020 We investigated the pathogenesis of pneumococcal pneumonia using clinical specimens collected for pneumonia surveillance in The Gambia. Lung aspirates and nasopharyngeal swabs from 31 patients were examined by culture, qPCR, whole genome sequencing ...
Dunne, EM +10 more
core +4 more sources
An economic analysis of a pneumococcal vaccine programme in people aged over 64 years in a developed country setting. [PDF]
, 2005 BACKGROUND: Polysaccharide pneumococcal vaccination for older adults is being introduced in developed country settings. Evidence of protection by this vaccine against pneumococcal pneumonia, or confirmation that illness and death from bacteraemia are ...
Cutts, Felicity T +3 more
core +1 more source
Increased pathogenicity of pneumococcal serotype 1 is driven by rapid autolysis and release of pneumolysin [PDF]
, 2020 Streptococcus pneumoniae serotype 1 is the predominant cause of invasive pneumococcal disease in sub-Saharan Africa, but the mechanism behind its increased invasiveness is not well understood.
Baltazar, Murielle +11 more
core +4 more sources
Clinical outcomes of pneumococcal pneumonia caused by antibiotic-resistant strains in Asian countries: a study by the Asian network for surveillance of resistant pathogens [PDF]
, 2004 To evaluate the clinical outcomes of pneumococcal pneumonia caused by antibiotic-resistant strains in Asian countries, we performed a prospective observational study of 233 cases of adult pneumococcal pneumonia in 9 Asian countries from January 2000 to ...
Carlos, Celia Carpio +19 more
core +1 more source
Estimating the burden of pneumococcal pneumonia among adults: a systematic review and meta-analysis of diagnostic techniques [PDF]
, 2016 Background: Pneumococcal pneumonia causes significant morbidity and mortality among adults. Given limitations of diagnostic tests for non-bacteremic pneumococcal pneumonia, most studies report the incidence of bacteremic or invasive pneumococcal disease (
Carratalà, Jordi +5 more
core +1 more source
IL-17 can be protective or deleterious in murine pneumococcal pneumonia [PDF]
, 2018 Streptococcus pneumoniae is the major bacterial cause of community-acquired pneumonia, and the leading agent of childhood pneumonia deaths worldwide. Nasal colonization is an essential step prior to infection.
Bayes, Hannah K. +4 more
core +3 more sources
Impact of Pneumococcal Conjugate Vaccines on Pneumonia Hospitalizations in High- and Low-Income Subpopulations in Brazil. [PDF]
, 2017 BackgroundPneumococcal conjugate vaccines (PCVs) are being used worldwide. A key question is whether the impact of PCVs on pneumonia is similar in low- and high-income populations.
Kürüm, Esra +7 more
core +2 more sources
Indirect effect of 7-valent and 13-valent pneumococcal conjugated vaccines on pneumococcal pneumonia hospitalizations in elderly [PDF]
, 2018 Background: Pneumonia is one of the leading causes of mortality and has a high burden in morbidity. In Portugal, 7-valent pneumococcal conjugated vaccine (PCV) was used since 2001 and PCV10/13 since 2009, being the last introduced into the National ...
Froes, Filipe +6 more
core +2 more sources
Epithelial cell–derived secreted and transmembrane 1a signals to activated neutrophils during pneumococcal pneumonia [PDF]
, 2016 Airway epithelial cell responses are critical to the outcome of lung infection. In this study, we aimed to identify unique contributions of epithelial cells during lung infection.
Belkina, Anna C. +12 more
core +1 more source