Challenges in estimating the impact of pneumococcal conjugate vaccines through surveillance [PDF]
SCOPUS: re.jinfo:eu-repo/semantics ...
Hanquet, Germaine, Vergison, Anne
core +1 more source
In vivo Neutralization of Pro-inflammatory Cytokines During Secondary Streptococcus pneumoniae Infection Post Influenza A Virus Infection [PDF]
An overt pro-inflammatory immune response is a key factor contributing to lethal pneumococcal infection in an influenza pre-infected host and represents a potential target for therapeutic intervention.
Boehme, Julia D. +8 more
core +1 more source
Genetic factors regulating lung vasculature and immune cell functions associate with resistance to pneumococcal infection [PDF]
Streptococcus pneumoniae is an important human pathogen responsible for high mortality and morbidity worldwide. The susceptibility to pneumococcal infections is controlled by as yet unknown genetic factors.
Jonczyk, Magda S. +7 more
core +5 more sources
A Trial of a 7-Valent Pneumococcal Conjugate Vaccine in HIV-Infected Adults. [PDF]
BACKGROUND: Streptococcus pneumoniae is a leading and serious coinfection in adults with human immunodeficiency virus (HIV) infection, particularly in Africa.
French, N +9 more
core +4 more sources
The TRIP database showed most Acute Respiratory Infections questions were already addressed by Cochrane reviews [PDF]
OBJECTIVE: Cochrane systematic reviews require more methodological support from Cochrane Review Groups (CRGs) than is customary in journals, CRGs must prioritise reviews to conserve resources.
Brassey, Jon +4 more
core +1 more source
No temporal association between influenza outbreaks and invasive pneumococcal infections [PDF]
Objective: To assess whether the influenza peak in populations precedes the annual peak for invasive pneumococcal infections (IPI) in winter.Design: Ecological study.
Arenz, Stephan +3 more
core +1 more source
Mortality from infectious pneumonia in metal workers: a comparison with deaths from asthma in occupations exposed to respiratory sensitizers [PDF]
Introduction: national analyses of mortality in England and Wales have repeatedly shown excess deaths from pneumonia in welders. During 1979-1990 the excess was attributable largely to deaths from lobar pneumonia and pneumonias other than ...
Brown, Terry +4 more
core +1 more source
PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao +16 more
wiley +1 more source
ABSTRACT Sutimlimab is a monoclonal antibody against complement fraction C1s approved for the treatment of hemolytic anemia due to cold agglutinin disease (CAD). Here, we analyzed and report the largest international CAD cohort of sutimlimab‐treated patients ever reported to highlight its safety and effectiveness in the real‐world setting. We accrued a
Bruno Fattizzo +38 more
wiley +1 more source
Abstract Background Current guidelines make no recommendations on discharge interventions or scheduling outpatient follow‐up after hospitlization for commnity‐acquired pneumonia (CAP). Objectives To assess the impact of scheduling early primary care follow‐up prior to discharge home among survivors of hypoxemic CAP hospitalizations.
Andrew J. Davis +12 more
wiley +1 more source

