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Pneumococcal Vaccines: Past Findings, Present Work, and Future Strategies [PDF]

open access: yesVaccines, 2021
The importance of Streptococcus pneumoniae has been well established. These bacteria can colonize infants and adults without symptoms, but in some cases can spread, invade other tissues and cause disease with high morbidity and mortality. The development
Giuliana S. Oliveira   +3 more
doaj   +2 more sources

Pneumococcal Vaccines

open access: yesMicrobiology Spectrum, 2019
Streptococcus pneumoniae is a Gram-Positive pathogen that is a major causative agent of pneumonia, otitis media, sepsis and meningitis across the world.
D. E. Briles   +4 more
doaj   +4 more sources

Uptake of Pneumococcal Vaccines Among U.S. Adults After 2022 Update to Recommendations [PDF]

open access: yesAJPM Focus
Introduction: Updated recommendations for adult pneumococcal vaccination in the U.S. (publication date: January 27, 2022) incorporated 2 new vaccines (15- and 20-valent pneumococcal conjugate vaccines), removed 13-valent pneumococcal conjugate vaccine ...
Ahuva Averin, MPP   +5 more
doaj   +2 more sources

Clonal expansion within pneumococcal serotype 6C after use of seven-valent vaccine [PDF]

open access: yes, 2013
Streptococcus pneumoniae causes invasive infections, primarily at the extremes of life. A seven-valent conjugate vaccine (PCV7) is used to protect against invasive pneumococcal disease in children.
Chan, Jacqueline   +10 more
core   +23 more sources

Bacterium-like Particles from Corynebacterium pseudodiphtheriticum as Mucosal Adjuvant for the Development of Pneumococcal Vaccines [PDF]

open access: yesVaccines
Previously, it was shown that intranasally (i.n.) administered Corynebacterium pseudodiphtheriticum 090104 (Cp) or CP-derived bacterium-like particles (BLPs) improve the immunogenicity of the pneumococcal conjugate vaccine (PCV).
Ramiro Ortiz Moyano   +10 more
doaj   +2 more sources

Review of global use of licensed vaccines and development of new vaccines for the prevention of pneumococcal infection

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2021
Streptococcus pneumoniae infection is the most common cause of high morbidity and mortality among children under 5 years of age, immunocompromised people, and the elderly.
M. V. Savkina   +6 more
doaj   +1 more source

Recent progress in pneumococcal protein vaccines

open access: yesFrontiers in Immunology, 2023
Pneumococcal infections continue to pose a significant global health concern, necessitating the development of effective vaccines. Despite the progress shown by pneumococcal polysaccharide and conjugate vaccines, their limited coverage and the emergence ...
Sha Li   +4 more
doaj   +1 more source

Pneumococcal vaccine [PDF]

open access: yesPostgraduate Medical Journal, 1997
Summary Streptococcus pneumoniae is a frequent cause of pneumonia and meningitis. This article looks at the pneumococcal vaccine, its uses, efficacy, and adverse effects and how vaccination may be improved. We also look at the role of the new conjugate vaccines.
K L, Hattotuwa, C R, Hind
openaire   +2 more sources

Development of Next Generation Streptococcus pneumoniae Vaccines Conferring Broad Protection

open access: yesVaccines, 2020
Streptococcus pneumoniae is a major pathogen causing pneumonia with over 2 million deaths annually, especially in young children and the elderly. To date, at least 98 different pneumococcal capsular serotypes have been identified. Currently, the vaccines
Malihe Masomian   +3 more
doaj   +1 more source

Emerging pneumococcal serotypes in Iraq: scope for improved vaccine development [version 2; peer review: 2 approved]

open access: yesF1000Research, 2023
Pneumococcal disease is a global public health concern as it affects the young, aged and the immunocompromised. The development of pneumococcal vaccines and their incorporation in the immunization programs has helped to reduce the global burden of ...
Ahmed H. Radhi   +4 more
doaj   +1 more source

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