Results 41 to 50 of about 32,416 (217)

CLINICAL AND IMMUNOLOGICAL EFFECT OF PNEUMOCOCCAL CONJUGATED VACCINES IN IMMUNOCOMPROMISED PATIENTS

Педиатрическая фармакология, 2010
Invasive pneumococcal infection is the most frequent cause of death in patients with immunodeficiences. The antibiotics used previously for prevention purposes are not efficient enough due to the developing antibiotic resistance.
A.A. Tarasova, M.P. Kostinov
doaj   +2 more sources

Cost effectiveness of pediatric pneumococcal conjugate vaccines: a comparative assessment of decision-making tools. [PDF]

, 2011
BACKGROUND: Several decision support tools have been developed to aid policymaking regarding the adoption of pneumococcal conjugate vaccine (PCV) into national pediatric immunization programs.
A.M. Henao, Henao, Ana Maria, J. Hombach, Hutubessy, Raymond, Edmunds, John W, Beutels, Philippe, Joachim Hombach, Hutubessy Raymond, R. Somkrua, Chaiyakunapruk, Nathorn, Hombach, Joachim, R. Hutubessy, John W Edmunds, Ana Maria Henao, Philippe Beutels, Hombach Joachim, Nathorn Chaiyakunapruk, Henao Ana Maria, Edmunds John W, P. Beutels, Somkrua, Ratchadaporn, Edmunds, John W., Melegaro, Alessia, N. Chaiyakunapruk, Ratchadaporn Somkrua, Chaiyakunapruk Nathorn, Beutels Philippe, Raymond Hutubessy, Melegaro Alessia, Somkrua Ratchadaporn, Alessia Melegaro, W.J. Edmunds   +31 more
core   +1 more source

Adult indication 13-valent pneumococcal conjugate vaccine clinical development overview: formulation, safety, immunogenicity (dosing and sequence), coadministration, and efficacy

Expert Review of Vaccines
Introduction There was no 13-valent pneumococcal conjugate vaccine (PCV13) adult antibody concentration threshold regulatory criterion for licensure – unlike the pediatric indication; consequently, for the adult indication, PCV13 serotype-specific ...
Mark A. Fletcher, Beate Schmoele-Thoma, Jelena Vojicic, Derek Daigle, Peter R. Paradiso, Graciela del Carmen Morales   +5 more
doaj   +1 more source

Environmental factors which can affect the burden of pneumococcal disease and the immune response to pneumococcal vaccines: the need for more precisely delineated vaccine recommendations

Expert Review of Vaccines, 2019
Introduction: Precision medicine describes the customization of healthcare tailored to the individual patient. Generally, vaccines are considered as public health tools rather than from the individual patient perspective.
Seong-Beom Park, Hyun-Jin Kim, Hee-Jin Cheong   +2 more
doaj   +1 more source

In‐line Raman spectroscopy real‐time glucose prediction method for commercial pneumococcal vaccine drug substance fermentation manufacturing process control

Biotechnology Progress, EarlyView.
Abstract Traditional off‐line analysis methods to quantify residual metabolite concentrations in a drug substance fermentation process consume valuable time, require costly resources, and demand potentially hazardous manual operations when working with pathogenic biological organisms.
Griffin P. Thomas, Brian C. Marks, Barbara B. Alvarado‐Hernandez, Matthew Woodling, James O'Connor, Roberto Ortiz, John Higgins, Jon Shanter   +7 more
wiley   +1 more source

A Trial of a 7-Valent Pneumococcal Conjugate Vaccine in HIV-Infected Adults. [PDF]

, 2010
BACKGROUND: Streptococcus pneumoniae is a leading and serious coinfection in adults with human immunodeficiency virus (HIV) infection, particularly in Africa.
Zijlstra, EE, Molyneux, Malcolm E, White, Sarah A., Mwaiponya, Martin, Mwalukomo, Thandie, Gordon, Stephen, Zijlstra, Eduard E, Longwe, Herbert, French, N, Mwalukomo, T, White, SA, French, Neil, Gordon, SB, Mwaiponya, M, Gilks, CF, Gilks, Charles F, Mwafulirwa, Gershom, Molyneux, Malcolm E., Mwafulirwa, G, Molyneux, ME, Gordon, Stephen B., Gordon, Stephen B, White, Sarah; id_orcid, Longwe, H, Gilks, Charles F., White, Sarah A, Zijlstra, Eduard E.   +26 more
core   +1 more source

ERA OF CONJUGATE VACCINES: INTERNATIONAL EXPERIENCE OF SUCCESSFUL APPLICATION

Педиатрическая фармакология, 2008
The article highlights comparative characteristics of the polysaccharide and conjugate vaccines against pneumococcal infection, meningococcosis and haemophilus influenza. The author stresses the advantage of the conjugate vaccines.
M.V. Fedoseenko, M.G. Galitskaya, L.S. Namazova   +2 more
doaj   +2 more sources

Next-Generation Whole-Cell Pneumococcal Vaccine

Vaccines, 2019
Streptococcus pneumoniae remains a major public health hazard. Although Pneumococcal Conjugate Vaccines (PCVs) are available and have significantly reduced the rate of invasive pneumococcal diseases, there is still a need for new vaccines with unlimited ...
Victor Morais, Esther Texeira, Norma Suarez   +2 more
doaj   +1 more source

Scheduling early primary care follow‐up after pneumonia: A retrospective target trial emulation in five hospitals

Journal of Hospital Medicine, EarlyView.
Abstract Background Current guidelines make no recommendations on discharge interventions or scheduling outpatient follow‐up after hospitlization for commnity‐acquired pneumonia (CAP). Objectives To assess the impact of scheduling early primary care follow‐up prior to discharge home among survivors of hypoxemic CAP hospitalizations.
Andrew J. Davis, Stephanie P. Taylor, Catherine L. Hough, Mari Armstrong‐Hough, Li Yan, Catherine K. Ettman, Katy Sadowski, Khyzer B. Aziz, Patrick G. Lyons, Katrina E. Hauschildt, Marc Kowalkowski, Eliana M. Perrin, Theodore J. Iwashyna   +12 more
wiley   +1 more source

Trends in hospitalizations for vaccine‐preventable diseases in the United States from 2014 to 2024

Journal of Hospital Medicine, EarlyView.
Abstract Background and Objectives Vaccination rates have declined in recent years, resulting in outbreaks of vaccine‐preventable diseases (VPDs) among children. We aimed to evaluate VPD hospitalization rates from 2014 to 2024 and to report associated trends in outcomes including intensive care utilization, mortality, readmissions, and costs.
Nathan M. Money, Erin Sullivan, Hannah Rector, Corrie E. McDaniel, Jessica L. Markham, Mersine A. Bryan   +5 more
wiley   +1 more source