Results 61 to 70 of about 27,136 (186)

The New Era of Pneumococcal Vaccination in Adults: What Is Next?

Vaccines
Streptococcus pneumoniae remains the leading cause of community-acquired pneumonia in adults and bacterial meningitis in children worldwide. In addition to pneumonia, invasive pneumococcal diseases (IPDs), such as bacteremia and meningitis, pose a ...
Lale Ozisik
doaj   +1 more source

Nonencapsulated Streptococcus pneumoniae: Emergence and Pathogenesis

mBio, 2016
While significant protection from pneumococcal disease has been achieved by the use of polysaccharide and polysaccharide-protein conjugate vaccines, capsule-independent protection has been limited by serotype replacement along with disease caused by ...
Lance E. Keller, D. Ashley Robinson, Larry S. McDaniel   +2 more
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, Volume 73, Issue 8, August 2026.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Prevention of pneumococcal diseases in the post-seven valent vaccine era: A European perspective

BMC Infectious Diseases, 2012
Background The burden of invasive pneumococcal disease in young children decreased dramatically following introduction of the 7-valent pneumococcal conjugate vaccine (PCV7). The epidemiology of S.
Weil-Olivier Catherine, van der Linden Mark, de Schutter Iris, Dagan Ron, Mantovani Lorenzo   +4 more
doaj   +1 more source

Neonatal Bloodstream Infections: A Narrative Review on Diagnostic and Therapeutic Challenges and Prospects in Developing Countries

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Bloodstream infections (BSIs) pose a significant global health challenge, particularly in developing countries. Neonates are highly vulnerable due to underdeveloped immune systems and immature physical barriers, a risk amplified by poor hygiene and limited healthcare access in low‐ and middle‐income countries (LMICs), leading to an ...
Alex Odoom, Abdul‐Halim Osman, Onyansaniba K. Ntim, Fleischer C. N. Kotey, Eric S. Donkor   +4 more
wiley   +1 more source

Prevalence, Antimicrobial Resistance, and Genetic Diversity of Non‐Typeable Streptococcus pneumoniae Carriage: A Systematic Review and Meta‐Analysis

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Non‐typeable Streptococcus pneumoniae (NT‐Sp) strains lack detectable capsules and are often missed by traditional serotyping. While associated primarily with asymptomatic carriage, NT‐Sp has emerged as a key player in antimicrobial resistance (AMR) gene dissemination and serotype replacement in the post‐vaccine era. This systematic
Robert K. Reeks, Onyansaniba K. Ntim, Eric S. Donkor   +2 more
wiley   +1 more source

Triptych of the Hermit Saints: pneumococcal polysaccharide vaccines for the elderly

Risk Management and Healthcare Policy, 2018
Ger T Rijkers,1,2 Laura IE Yousif,1 Simone MC Spoorenberg,3 Frans J van Overveld1 1Department of Science, University College Roosevelt, Middelburg, the Netherlands; 2Department of Medical Microbiology and Immunology, St. Antonius Hospital ...
Rijkers GT, Yousif LIE, Spoorenberg SMC, van Overveld FJ   +3 more
doaj  

Overwhelming Post‐Splenectomy Sepsis From Capnocytophaga canimorsus

International Journal of Laboratory Hematology, EarlyView.
Maitlyn Hsia, Maud Ahmad, Cyrus C. Hsia, Benjamin Chin‐Yee   +3 more
wiley   +1 more source

Unveiling Gut Homeostasis Disruption in Sepsis: Towards an Integrated Mechanistic and Translational Roadmap

Cell Proliferation, Volume 59, Issue 8, August 2026.
Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao, Lin Qi, Guijun Zou, Xingpeng Yang, Yizhao Ma, Zhifu Li, Xiaohui Du, Pengyue Zhao   +7 more
wiley   +1 more source

Novel processes to obtain pneumococcal surface proteins for vaccines

Applied Microbiology and Biotechnology
Current pneumococcal vaccines are based on the protection offered by capsular polysaccharides from only a few from > 100 serotypes; therefore, serotype-independent vaccines composed of pneumococcal surface proteins are being developed.
Viviane Maimoni Gonçalves
doaj   +1 more source