Pneumococcal carriage in sub-Saharan Africa--a systematic review. [PDF]
BACKGROUND: Pneumococcal epidemiology varies geographically and few data are available from the African continent. We assess pneumococcal carriage from studies conducted in sub-Saharan Africa (sSA) before and after the pneumococcal conjugate vaccine (PCV)
Bottomley, Christian +15 more
core +1 more source
Cellular immunity to Streptococcus pneumoniae: implications for vaccine-mediated prevention
Introduction Streptococcus pneumoniae asymptomatically colonizes the nasopharynx but can also cause mucosal infections or invasive pneumococcal disease.
Heather VanSeggelen +7 more
doaj +1 more source
Safety and Efficacy of Pneumococcal Vaccination in Pediatric Nephrotic Syndrome
Nephrotic syndrome affects both children and adults. Idiopathic nephrotic syndrome is reported to be one of the most frequent renal pathologies in childhood.
Shamitha Thishakya Goonewardene +16 more
doaj +1 more source
Surveillance of invasive pneumococcal disease in 30 EU countries: Towards a European system?
In this era of new pneumococcal conjugate vaccines (PCV), we described and compared surveillance of invasive pneumococcal disease (IPD) and PCV policies in 30 European countries to provide guidance for Europe-wide surveillance.
Perrocheau, Anne +31 more
core +1 more source
Meningococcal and pneumococcal meningitis in Northern Ghana [PDF]
Despite improvements in technology, treatments and understanding of how bacterial meningitis develops, the disease remains a potentially life-threatening emergency capable of causing significant morbidity and mortality. N. meningitidis, S.
Forgor, Abdulai Adams
core +1 more source
Trained Immunity in Childhood Vaccination
Trained immunity as an emerging concept in paediatric vaccinology. Trained immunity links vaccine stimuli through epigenetic and metabolic reprogramming to enhanced innate immune cell function, thereby strengthening protection against diverse pathogens while promoting adaptive immune responses through more efficient antigen presentation and co ...
ChenRongRong Cai +2 more
wiley +1 more source
Common NFKBIL2 polymorphisms and susceptibility to pneumococcal disease: a genetic association study. [PDF]
INTRODUCTION: Streptococcus pneumoniae remains a major global health problem and a leading cause of death in children worldwide. The factors that influence development of pneumococcal sepsis remain poorly understood, although increasing evidence points ...
Rautanen, Anna +51 more
core +1 more source
Pneumococcal serotype-specific antibodies persist through early childhood after infant immunization: follow-up from a randomized controlled trial [PDF]
BACKGROUND: In a previous UK multi-center randomized study 278 children received three doses of 7-valent (PCV-7) or 13-valent (PCV-13) pneumococcal conjugate vaccine at 2, 4 and 12 months of age.
Trück, J +50 more
core +1 more source
Abstract Background Vaccination is effective at preventing severe illness related to influenza, pneumococcal disease and coronavirus disease 2019 COVID‐19. Vaccine coverage among older Australians is incomplete, and hospitals currently administer very few vaccine doses.
Victoria Deacon +5 more
wiley +1 more source
Dynamic models of pneumococcal carriage and the impact of the Heptavalent Pneumococcal Conjugate Vaccine on invasive pneumococcal disease. [PDF]
BACKGROUND: The 7-valent pneumococcal conjugate vaccine has been introduced in national immunisation programmes of most industrialised countries and recently in two African GAVI eligible countries (Rwanda and The Gambia). However the long term effects of
George, Robert +24 more
core +2 more sources

