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Postgraduate Medical Journal, 1997 Summary Streptococcus pneumoniae is a frequent cause of pneumonia and meningitis. This article looks at the pneumococcal vaccine, its uses, efficacy, and adverse effects and how vaccination may be improved. We also look at the role of the new conjugate vaccines.
K L, Hattotuwa, C R, Hind
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Development of Next Generation Streptococcus pneumoniae Vaccines Conferring Broad Protection
Vaccines, 2020 Streptococcus pneumoniae is a major pathogen causing pneumonia with over 2 million deaths annually, especially in young children and the elderly. To date, at least 98 different pneumococcal capsular serotypes have been identified. Currently, the vaccines
Malihe Masomian +3 more
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Efficacy and effectiveness of extended-valency pneumococcal conjugate vaccines [PDF]
Korean Journal of Pediatrics, 2014 The 7-valent pneumococcal protein conjugate vaccine (PCV7) has been shown to be highly efficacious against invasive pneumococcal diseases and effective against pneumonia and in reducing otitis media. The introduction of PCV7 has resulted in major changes
Hyunju Lee, Eun Hwa Choi, Hoan Jong Lee
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F1000Research, 2023 Pneumococcal disease is a global public health concern as it affects the young, aged and the immunocompromised. The development of pneumococcal vaccines and their incorporation in the immunization programs has helped to reduce the global burden of ...
Ahmed H. Radhi +4 more
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The COVID-19 pandemic increased the demand for pneumococcal vaccination in Japan
Human Vaccines & Immunotherapeutics, 2021 Although routine vaccinations in children decreased during the coronavirus disease 2019 (COVID-19) pandemic, pneumococcal vaccine coverage in older adults has remained unknown.
Akira Komori +2 more
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Pneumococcal Choline-Binding Proteins Involved in Virulence as Vaccine Candidates
Vaccines, 2021 Streptococcus pneumoniae is a pathogen responsible for millions of deaths worldwide. Currently, the available vaccines for the prevention of S.
Julio Sempere +5 more
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BMC Public Health, 2019 Background Streptococcus pneumoniae causes substantial morbidity and mortality among children. The introduction of pneumococcal conjugate vaccines (PCV) has the potential to dramatically reduce disease burden.
S. F. La Vincente +18 more
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Adult pneumococcal vaccination – new opportunities
Family Medicine & Primary Care Review, 2023 Pneumococcal infections (Streptococcus pneumoniae) remain a significant epidemiological problem globally. Although an invasive pneumo-coccal disease (IPD), which includes meningitis, sepsis and pneumonia with bacteremia, is the most severe form of ...
ERNEST KUCHAR +13 more
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30-Minute Highly Multiplexed VaxArray Immunoassay for Pneumococcal Vaccine Antigen Characterization
Vaccines, 2022 Pneumonia accounts for over 20% of deaths worldwide in children aged 1 to 5 years, disproportionately affecting lower- and middle-income countries.
Tianjing Hu +11 more
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Vaccines, 2020 Various studies indicate that vaccination, especially with pneumococcal vaccines, protects against symptomatic cases of SARS-CoV-2 infection and death.
Robert Root-Bernstein
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