Results 41 to 50 of about 417,620 (216)

The anticipated severity of a "1918-like" influenza pandemic in contemporary populations: the contribution of antibacterial interventions. [PDF]

PLoS ONE, 2012
Recent studies have shown that most of deaths in the 1918 influenza pandemic were caused by secondary bacterial infections, primarily pneumococcal pneumonia.
Yu-Wen Chien, Bruce R Levin, Keith P Klugman   +2 more
doaj   +1 more source

MicroRNA-223 Dampens Pulmonary Inflammation during Pneumococcal Pneumonia

Cells, 2023
Community-acquired pneumonia remains a major contributor to global communicable disease-mediated mortality. Neutrophils play a leading role in trying to contain bacterial lung infection, but they also drive detrimental pulmonary inflammation, when ...
Cengiz Goekeri, Peter Pennitz, Wibke Groenewald, Ulrike Behrendt, Holger Kirsten, Christian M. Zobel, Sarah Berger, Gitta A. Heinz, Mir-Farzin Mashreghi, Sandra-Maria Wienhold, Kristina Dietert, Anca Dorhoi, Achim D. Gruber, Markus Scholz, Gernot Rohde, Norbert Suttorp, CAPNETZ Study Group, Martin Witzenrath, Geraldine Nouailles   +18 more
doaj   +1 more source

Scheduling early primary care follow‐up after pneumonia: A retrospective target trial emulation in five hospitals

Journal of Hospital Medicine, EarlyView.
Abstract Background Current guidelines make no recommendations on discharge interventions or scheduling outpatient follow‐up after hospitlization for commnity‐acquired pneumonia (CAP). Objectives To assess the impact of scheduling early primary care follow‐up prior to discharge home among survivors of hypoxemic CAP hospitalizations.
Andrew J. Davis, Stephanie P. Taylor, Catherine L. Hough, Mari Armstrong‐Hough, Li Yan, Catherine K. Ettman, Katy Sadowski, Khyzer B. Aziz, Patrick G. Lyons, Katrina E. Hauschildt, Marc Kowalkowski, Eliana M. Perrin, Theodore J. Iwashyna   +12 more
wiley   +1 more source

Effect of 10-valent pneumococcal conjugate vaccine on the incidence of radiologically-confirmed pneumonia and clinically-defined pneumonia in Kenyan children: an interrupted time-series analysis

Lancet Global Health, 2019
Summary Background Pneumococcal conjugate vaccines (PCV) are highly protective against invasive pneumococcal disease caused by vaccine serotypes, but the burden of pneumococcal disease in low-income and middle-income countries is dominated by pneumonia ...
Micah Silaba, Michael Ooko, C. Bottomley, J. Sande, R. Benamore, Kate Park, James Ignas, Kathryn Maitland, Kathryn Maitland, N. Mturi, Anne Makumi, M. Otiende, S. Kagwanja, Sylvester Safari, V. Ochola, Tahreni Bwanaali, Tahreni Bwanaali, E. Bauni, E. Bauni, F. Gleeson, M. Knoll, I. Adetifa, I. Adetifa, Kevin Marsh, Kevin Marsh, T. N. Williams, T. N. Williams, Tatu Kamau, S. Sharif, O. Levine, L. Hammitt, L. Hammitt, J. Scott   +32 more
semanticscholar   +1 more source

Trends in hospitalizations for vaccine‐preventable diseases in the United States from 2014 to 2024

Journal of Hospital Medicine, EarlyView.
Abstract Background and Objectives Vaccination rates have declined in recent years, resulting in outbreaks of vaccine‐preventable diseases (VPDs) among children. We aimed to evaluate VPD hospitalization rates from 2014 to 2024 and to report associated trends in outcomes including intensive care utilization, mortality, readmissions, and costs.
Nathan M. Money, Erin Sullivan, Hannah Rector, Corrie E. McDaniel, Jessica L. Markham, Mersine A. Bryan   +5 more
wiley   +1 more source

Impact of pneumococcal conjugate vaccines on hospitalizations for pneumonia in the United States

Expert Review of Vaccines, 2019
Introduction: Pneumonia is one of the leading causes of morbidity and mortality among children and older adults. Pneumococcal conjugate vaccines (PCVs) were introduced into the US routine infant vaccination schedule leading to substantial reductions of ...
Andrew D. Wiese, M. Griffin, Carlos G. Grijalva   +2 more
semanticscholar   +1 more source

Infection risk in rheumatoid arthritis patients treated with biologic and targeted therapies

Rheumatology &Autoimmunity, EarlyView.
In this context, infections associated with each biologic and targeted drug are summarized to inform the stratification of RA patients, including the characteristics of the susceptible patients and their concomitant therapy. We aim to provide a benefit‐risk analysis for clinical decision, and vital indications for the prevention of highly correlated ...
Lujing Wang, Jieshi Lin, Jie Qian
wiley   +1 more source

A population-based study on the burden of hospitalized pediatric pneumococcal disease in Taiwan before and after the introduction of 13-valent pneumococcal conjugate vaccine into the childhood immunization program in 2015

BMC Infectious Diseases
Background To estimate the burden of invasive pneumococcal disease, non-bacteremic pneumococcal pneumonia, and acute otitis media before and after inclusion of the 13-valent pneumococcal vaccine (PCV13) into Taiwan’s Childhood Immunization Program in ...
Ting-An Yen, Jhong-Lin Wu, Chi-Chuan Wang, Ling-Ya Huang, See-Hwee Yeo, Dony Patel, Cindy Thiow Koon Lim, Hung-Wei Lin, Eriko Yamada, Isaya Sukarom   +9 more
doaj   +1 more source

A model for predicting bacteremia in patients with community-acquired pneumococcal pneumonia: a retrospective observational study

BMC Pulmonary Medicine, 2018
Background Pneumococcal pneumonia causes high morbidity and mortality among adults. This study aimed to identify risk factors for bacteremic pneumococcal pneumonia, and to construct a prediction model for the development of bacteremia in patients with ...
Yasuyoshi Washio, Akihiro Ito, Shogo Kumagai, Tadashi Ishida, Akio Yamazaki   +4 more
doaj   +1 more source

Pathogenesis and prevention of risk of cardiovascular events in patients with pneumococcal community‐acquired pneumonia

Journal of Internal Medicine, 2019
It is now well recognized that cardiovascular events (CVE) occur quite commonly, both in the acute phase and in the long‐term, in patients with community‐acquired pneumonia (CAP).
C. Feldman, S. Normark, B. Henriques‐Normark, R. Anderson   +3 more
semanticscholar   +1 more source