Results 51 to 60 of about 417,620 (216)

Antimicrobial Resistance in Children With Bloodstream Infections: A Population‐Based Study in Stockholm, Sweden

Acta Paediatrica, EarlyView.
ABSTRACT Aim We retrospectively evaluated trends in antimicrobial resistance (AMR) in paediatric bloodstream infections and assessed changes in antimicrobial prescription patterns over a 20‐year period. Methods We analysed positive blood cultures from children admitted with suspected serious infection between 1998 and 2018.
Joachim Luthander, Rutger Bennet, Per Nydert, Margareta Eriksson, Christian G. Giske, Anna Nilsson   +5 more
wiley   +1 more source

Retrospective database analysis for clinical diagnoses commonly associated with pneumococcal diseases in the Malaysian healthcare system over a 3-year period (2013–2015)

BMC Infectious Diseases
Background Pneumococcal disease caused by Streptococcus pneumoniae is an important cause of morbidity and mortality across all ages, particularly in younger children and older adults. Here, we describe pneumococcal disease hospitalizations at Ministry of
Saravanan S. R. Sundaramurthy, Kristen E. Allen, Mark A. Fletcher, Kok Fui Liew, Boekhtiar Borhanuddin, Mohammad Ali, Graciela Morales, Bradford Gessner, Jerusha Naidoo, Jo Southern   +9 more
doaj   +1 more source

A Retrospective Study of the Clinical Burden of Hospitalized All-Cause and Pneumococcal Pneumonia in Canada

Canadian Respiratory Journal, 2016
Background. Routine vaccination against Streptococcus pneumoniae is recommended in Canada for infants, the elderly, and individuals with chronic comorbidity.
Shelly A. McNeil, Nawab Qizilbash, Jian Ye, Sharon Gray, Giovanni Zanotti, Samantha Munson, Nathalie Dartois, Craig Laferriere   +7 more
doaj   +1 more source

Effectiveness of 13-Valent Pneumococcal Conjugate Vaccine Against Hospitalization for Community-Acquired Pneumonia in Older US Adults: A Test-Negative Design

Clinical Infectious Diseases, 2018
Our study demonstrated real-world, direct effectiveness of 13-valent pneumococcal conjugate vaccine against vaccine-type community-acquired pneumonia following introduction into a routine immunization program among adults aged ≥65 years, many of whom had
J. McLaughlin, Q. Jiang, R. Isturiz, H. Sings, D. Swerdlow, B. Gessner, R. Carrico, P. Peyrani, T. Wiemken, William A. Mattingly, J. Ramirez, L. Jodar   +11 more
semanticscholar   +1 more source

Unveiling Gut Homeostasis Disruption in Sepsis: Towards an Integrated Mechanistic and Translational Roadmap

Cell Proliferation, EarlyView.
Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao, Lin Qi, Guijun Zou, Xingpeng Yang, Yizhao Ma, Zhifu Li, Xiaohui Du, Pengyue Zhao   +7 more
wiley   +1 more source

Herd effects of child vaccination with pneumococcal conjugate vaccine against pneumococcal non-invasive community-acquired pneumonia: What is the evidence?

Human Vaccines & Immunotherapeutics, 2017
Quantification of pneumococcal conjugate vaccines (PCVs) herd effects are mainly performed on invasive pneumococcal disease (IPD) but there is conflicting evidence regarding herd effects of PCVs on non-IPD pneumococcal community-acquired pneumonia.
Cornelis H. van Werkhoven
doaj   +1 more source

Pneumococcal pneumonia prevalence among adults with severe acute respiratory illness in Thailand - comparison of Bayesian latent class modeling and conventional analysis

BMC Infectious Diseases, 2019
Background Determining the etiology of pneumonia is essential to guide public health interventions. Diagnostic test results, including from polymerase chain reaction (PCR) assays of upper respiratory tract specimens, have been used to estimate prevalence
Ying Lu, Lawrence Joseph, Patrick Bélisle, Pongpun Sawatwong, Anchalee Jatapai, Toni Whistler, Somsak Thamthitiwat, Wantana Paveenkittiporn, Supphacoke Khemla, Chris A. Van Beneden, Henry C. Baggett, Christopher J. Gregory   +11 more
doaj   +1 more source

Risk Factors of Blood Culture Positivity and Mortality in Bloodstream Infections: A Population‐Based Study of Patients With B‐Cell Malignancies

European Journal of Haematology, EarlyView.
ABSTRACT Background Bloodstream infections remain a major cause of mortality among cancer patients. Pathogen surveillance and risk stratification tools are key to improved management. This study describes trends in causative pathogens and explores risk factors for positive blood cultures (PBCs) and post‐infection mortality in cancer patients.
Mathias Holmsgaard Eskesen, Alexander Djupnes Fuglkjær, Tarec Christoffer El‐Galaly, Paw Jensen, Izabela Ewa Nielsen, Laurids Østergaard Poulsen, Mikkel Runason Simonsen, Kirstine Kobberøe Søgaard   +7 more
wiley   +1 more source

Animal Models of Pneumococcal pneumonia

International Journal of Molecular Sciences, 2019
Streptococcus pneumoniae remains the most common bacterial pathogen causing lower respiratory tract infections and is a leading cause of morbidity and mortality worldwide, especially in children and the elderly.
N. Borsa, M. D. Di Pasquale, M. Restrepo
semanticscholar   +1 more source

Legionella pneumophila pneumonia in South Eastern Sydney: diagnosis, prognosis and public health outcomes

Internal Medicine Journal, EarlyView.
Abstract Background Legionellosis causes more severe disease than other aetiologies of community‐acquired pneumonia (CAP). Early recognition and treatment of Legionella pneumonia reduce mortality. Urinary antigen testing (UAT) has facilitated rapid and reliable diagnosis of Legionella pneumonia. Aims The aims of this study were as follows: (i) identify
Sue Qian, Nickson Ning, Kelli Snyders, Misha Klingstrom, Pam Konecny, Vicky Sheppeard, Rachael Roberts, Georgia Shimmin, Robert Stevens, Richard Sullivan   +9 more
wiley   +1 more source