Results 71 to 80 of about 417,620 (216)
The Role of Polyphenols in Respiratory and Gut Health: From the Perspective of Gut‐Lung Axis
ABSTRACT The gut‐lung axis constitutes a dynamic, multidirectional communication platform between the gastrointestinal and respiratory tracts. Its complexity arises from the integrated crosstalk among the microbiota, immune system, and redox homeostasis, collectively influencing disease susceptibility and progression.
Jian Kang +7 more
wiley +1 more source
Excessive activation of neutrophils results in the release of neutrophil elastase (NE), which leads to lung injury in severe pneumonia. Previously, we demonstrated a novel immune subversion mechanism involving microbial exploitation of this NE ability ...
H. Domon +10 more
semanticscholar +1 more source
ABSTRACT Sutimlimab is a monoclonal antibody against complement fraction C1s approved for the treatment of hemolytic anemia due to cold agglutinin disease (CAD). Here, we analyzed and report the largest international CAD cohort of sutimlimab‐treated patients ever reported to highlight its safety and effectiveness in the real‐world setting. We accrued a
Bruno Fattizzo +38 more
wiley +1 more source
Pneumococcal (Pneumonia) Vaccines [PDF]
Phalgoon, Shah +3 more
openaire +2 more sources
ABSTRACT Background and Aim Pneumonia contributes substantially to the childhood mortality burden in low and middle‐income countries (LMICs). Reported predictors of mortality in childhood pneumonia in LMIC are varied. This study aimed to describe predictors of mortality among children with pneumonia in a tertiary hospital in Ghana.
Sandra Kwarteng Owusu +17 more
wiley +1 more source
ABSTRACT Background Pneumococcus are often found in the respiratory tract of healthy people, especially children, and are a common cause of infections such as otitis media, sinusitis, conjunctivitis and community‐acquired pneumonia. In other cases, the bacteria can cause more serious conditions known collectively as invasive pneumococcal disease (IPD),
Pamela Di Giovanni +9 more
wiley +1 more source
Pyroptosis maintains immune homeostasis by eliminating damaged or infected cells, but its dysregulation promotes inflammation and cancer progression. The diagram illustrates key activation pathways, links with other programmed cell deaths, and cancer‐specific effects, enhancing its dual protective and pathogenic roles.
Diego Liviu Boaru +18 more
wiley +1 more source
Are the pneumococcal polysaccharide vaccines effective? Meta-analysis of the prospective trials
The objective was to review the evidence of effectiveness of the polyvalent polysaccharide pneumococcal vaccine from prospective properly randomised controlled trials comparing pneumococcal vaccines with placebo in subjects who are immunocompetent and ...
Lipsky Benjamin A +2 more
doaj +1 more source
ABSTRACT Background As overall survival improves in metastatic hormone‐sensitive prostate cancer (mHSPC), non‐cancer causes of death are increasingly relevant. Methods We conducted a real‐world multicenter study of patients diagnosed with mHSPC treated with ADT alone or in combination. Causes of death before progression to castration‐resistant prostate
Marta Garcia de Herreros +15 more
wiley +1 more source

