Results 41 to 50 of about 68,845 (338)

Internalisation of membrane progesterone receptor-α after treatment with progesterone: Potential involvement of a clathrin-dependent pathway [PDF]

, 2009
This article has been made available through the Brunel Open Access Publishing Fund.Internalisation and recycling of seven trans-membrane domain receptors is a critical regulatory event for their signalling.
Dong, J, Foster, H, Karteris, E, Reynolds, A, Stenbeck, G, Thomas, P   +5 more
core   +1 more source

Fertility-sparing treatment in early endometrial cancer: current state and future strategies [PDF]

Obstetrics & Gynecology Science, 2020
Endometrial cancer (EC) is the fifth most common cancer in women worldwide. Global estimates show rising incidence rates in both developed and developing countries.
Andreas Obermair, Eva Baxter, Donal J. Brennan, Jessica N. McAlpine, Jennifer J. Muellerer, Frédéric Amant, Mignon D. J. M. van Gent, Robert L. Coleman, Shannon N. Westin, Melinda S. Yates, Camilla Krakstad, Monika Janda   +11 more
doaj   +1 more source

Association between diabetes, diabetes treatment and risk of developing endometrial cancer. [PDF]

, 2014
BackgroundA growing body of evidence suggests that diabetes is a risk factor for endometrial cancer incidence. However, most of these studies used case-control study designs and did not adjust for obesity, an established risk factor for endometrial ...
Beresford, S, Chen, C, Chlebowski, R, Garcia, L, Kuller, L, Luo, J, Margolis, KL, Regier, M, Wactawski-Wende, J   +8 more
core   +2 more sources

Estradiol, Progesterone, and Transforming Growth Factor α Regulate Insulin-Like Growth Factor Binding Protein-3 (IGFBP3) Expression in Mouse Endometrial Cells [PDF]

, 2009
Insulin-like growth factor 1 (IGF1) Is Involved in the proliferation of mouse and rat endometrial cells in a paracrine or autocrine manner. Insulin-like growth factor binding protein-3 (IGFBP3) modulates actions of IGFs directly or indirectly.
Hembree JR, Huynh H, Munetoshi Kanayama, Ohtsuki T, Ohtsuki T, Pierro E, Sakae Takeuchi, Shiraga M, Sumio Takahashi, Takaoka M, Tetsuya Maekawa   +10 more
core   +1 more source

Progesterone Receptor Status Predicts Response to Progestin Therapy in Endometriosis

Journal of Clinical Endocrinology and Metabolism, 2018
Context Progestin-based therapy is the first-line treatment for managing endometriosis-associated pain. However, response to progestins is currently variable and unpredictable.
V. Flores, A. Vanhie, Tran Dang, H. Taylor   +3 more
semanticscholar   +1 more source

Metabolic, inflammatory and haemostatic effects of a low-dose continuous combined HRT in women with type 2 diabetes: potentially safer with respect to vascular risk? [PDF]

, 2003
BACKGROUND Conventional hormone replacement therapy (HRT) containing conjugated equine oestrogen (CEE) and medroxyprogesterone acetate (MPA) increases triglyceride, C- reactive protein (CRP) and coagulation Factor VII concentrations, potentially ...
Alan J. Jaap, Andersen, Anderson, Ann Rumley, Anne Kelly, Brussard, Cushman, Dichtl, Ferrara, Gordon D. Lowe, Gornstein, Herrington, Hokanson, Hulley, Ian A. Greer, John R. Petrie, Joyce McKenzie, Kanaya, Kenneth Paterson, Knopp, Koh, Kroon, Kroon, Lokkegaard, Lowe, Lowe, Lowe, Lynne Crawford, Manning, Meade, Naveed Sattar, Perera, Petitti, Pradhan, Rapp, Ridker, Ridker, Rossouw, Sattar, Sattar, Stephen Gallacher, Stork, Van Baal, Van Baal, Vehkavaara, Woodward, Zanger   +46 more
core   +1 more source

The potential influence of estrogen-containing oral contraception on clozapine metabolism in a patient with known pharmacogenomic status [PDF]

Mental Health Clinician
Clozapine is primarily metabolized via cytochrome P450(CYP)1A2 and to a lesser extent CYP3A4, CYP2C19, and CYP2D6. Metabolic inhibitors of clozapine, such as fluvoxamine and ciprofloxacin, are important to recognize to avoid adverse drug events. Estrogen-
Alyssa K. Kuhn, Meina L. Determan, Jessica A. Wright, PharmD, Eric Matey, Jonathan G. Leung   +4 more
doaj   +1 more source

Effects of Oral Contraceptive Androgenicity on Visuospatial and Social-Emotional Cognition: A Prospective Observational Trial

Brain Sciences, 2020
Oral contraceptives (OCs) containing estrogen and progesterone analogues are widely used amongst reproductive-aged women, but their neurocognitive impact is poorly understood.
Caroline Gurvich, Annabelle M. Warren, Roisin Worsley, Abdul-Rahman Hudaib, Natalie Thomas, Jayashri Kulkarni   +5 more
doaj   +1 more source

Breast Cancer Risk with Progestin Subdermal Implants: A Challenge in Patients Counseling

Frontiers in Endocrinology, 2021
There is a steady global rise in the use of progestin subdermal implants, where use has increased by more than 20 times in the past two decades. BC risk has been reported with the older progestin only methods such as oral pills, injectables, and ...
Ghada Mohammed, Noha A. Mousa, Iman M. Talaat, Iman M. Talaat, Haya Ibrahim, Maha Saber-Ayad, Maha Saber-Ayad   +6 more
doaj   +1 more source

Ovarian function during hormonal contraception assessed by endocrine and sonographic markers: a systematic review [PDF]

, 2016
This systematic review focuses on the literature evidence for residual ovarian function during treatment with hormonal contraceptives. We reviewed all papers which assessed residual ovarian activity during hormonal contraceptive use, using endocrine ...
Bastianelli, Carlo, Candelieri, Miriam, D'Arpe, Stella, DI FELICIANTONIO, Mara, Franceschetti, Silvia, Piccioni, Maria Grazia   +5 more
core   +1 more source