Results 41 to 50 of about 702,734 (359)

The CRASH trial: the first large-scale, randomised, controlled trial in head injury. [PDF]

, 2001
The global epidemic of head injuries is just beginning. Many are caused by road traffic crashes. It is estimated that, by 2020, road traffic crashes will have moved from its present position of ninth to third in the world disease burden ranking, as ...
Roberts, I
core   +2 more sources

Randomised controlled trials [PDF]

Postgraduate Medical Journal, 1999
Randomised controlled trials , Alejandro Jadad, pp 128. BMJ Books, 1998. £12.95 (£11.95 to BMA members), paperback. ISBN 0 7279 1208 9. ★★★ The issue of trial design is increasingly recognised as central to the evaluation of the benefit from any healthcare intervention.
openaire   +2 more sources

Early antiviral treatment in outpatients with COVID-19 (FLARE): a structured summary of a study protocol for a randomised controlled trial

Trials, 2021
Objectives The objective of this trial is to assess whether early antiviral therapy in outpatients with COVID-19 with either favipiravir plus lopinavir/ritonavir, lopinavir/ritonavir alone, or favipiravir alone, is associated with a decrease in viral ...
Li-An K. Brown, Nick Freemantle, Judy Breuer, Hakim-Moulay Dehbi, Kashfia Chowdhury, Gemma Jones, Felicia Ikeji, Amalia Ndoutoumou, Krishneya Santhirakumar, Nicky Longley, Anna M. Checkley, Joseph F. Standing, David M. Lowe   +12 more
doaj   +1 more source

IJCM_25A: Effect of one-to-one counselling of mothers attending an immunization clinic on breastfeeding among infants- A Randomised Controlled Trial

Indian Journal of Community Medicine
Background: To improve breastfeeding practices, many interventions have been studied at various critical contact points. Our study aimed to improve exclusive breastfeeding by integrating a limited number of counselling sessions with routine immunization ...
Maiti Urmimala, Maroof Khan Amir, Bhasin S K, Shah Dheeraj   +3 more
doaj   +1 more source

Ondansetron for irritable bowel syndrome with diarrhoea: randomised controlled trial

Efficacy and Mechanism Evaluation, 2023
Background Irritable bowel syndrome with diarrhoea is characterised by frequent, loose or watery stools with associated urgency, resulting in marked reduction of quality of life. Ondansetron, a 5-hydroxytryptamine-3 receptor antagonist, has been shown to
David Gunn, Rabia Topan, Ron Fried, Ivana Holloway, Richard Brindle, Suzanne Hartley, Lorna Barnard, Maura Corsetti, S Mark Scott, Adam Farmer, Ayesha Akbar, Maria Eugenicos, Nigel Trudgill, Kapil Kapur, John McLaughlin, David S Sanders, Arvind Ramadas, Peter Whorwell, Lesley Houghton, Phil G Dinning, Qasim Aziz, Alexander C Ford, Amanda Farrin, Robin Spiller   +23 more
doaj   +1 more source

A single blind, multicenter, randomized controlled trial to evaluate the effectiveness and cost of a novel nutraceutical (LopiGLIK®) lowering cardiovascular disease risk [PDF]

, 2018
Context: Cardiovascular disease (CVD) costs the economy €210 billion per year in Europe. There is an association between low-density lipoprotein cholesterol (LDL-C) and CVD risk.
Izzo, Raffaele, Manfrin, Andrea, Manzi, Maria Virginia, Rozza, Francesco, Trimarco, Valentina   +4 more
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A systematic review of randomised controlled trials on the effectiveness of exercise programs on lumbo pelvic pain among postnatal women [PDF]

, 2015
Background: A substantial number of women tend to be affected by Lumbo Pelvic Pain (LPP) following child birth. Physical exercise is indicated as a beneficial method to relieve LPP, but individual studies appear to suggest mixed findings about its ...
A Garshasbi, A Gutke, A Gutke, A Gutke, A Gutke, A Tanvi, A Vleeming, AB Granath, AG Cramp, B Stuge, B Stuge, C Richardson, CB Olsson, CB Olsson, CD Skaggs, CF Yan, CG Maher, DB Stapleton, E Kontopantelis, E Líndal, E Thorell, EC Larsen, EK Bjelland, HM McCormack, HS Robinson, HS Robinson, HY Chang, I Mogren, IM Mogren, J Walker, JM Kendall, JM Mens, JM Mens, K Björklund, K Gjestland, L Nilsson-Wikmar, L Nilsson‐Wikmar, L Norén, M Kumle, M Perry, MA Mohseni-Bandpei, Meei-Ling Gau, NA Al‐Sayegh, NC Foley, NK Vøllestad, NN Ansari, O Airaksinen, O Ayanniyi, Pei-Ching Tseng, S Chaudry, S Malmqvist, SA Olivo, Shuby Puthussery, SM Wang, WWK To, Y Ko, Yannis Pappas, YL Ko   +57 more
core   +1 more source

Understanding controlled trials: Randomisation methods in controlled trials

BMJ, 1998
The main purpose of randomisation is to avoid bias by distributing the characteristics of patients that may influence outcome randomly between treatment groups so that any difference in outcome can be explained only by treatment. These characteristics might be demographic ones such age or prognostic factors such as clinical history or disease severity.
Roberts, C., Torgerson, D.
openaire   +5 more sources

The Hawthorne Effect: a randomised, controlled trial [PDF]

BMC Medical Research Methodology, 2007
Abstract Background The 'Hawthorne Effect' may be an important factor affecting the generalisability of clinical research to routine practice, but has been little studied. Hawthorne Effects have been reported in previous clinical trials in dementia but to our knowledge, no attempt has been made to quantify them.
McCarney, R, Warner, J, Iliffe, S, van Haselen, R, Griffin, M, Fisher, P   +5 more
openaire   +5 more sources

The combined diabetes and renal control trial (C-DIRECT) - a feasibility randomised controlled trial to evaluate outcomes in multi-morbid patients with diabetes and on dialysis using a mixed methods approach [PDF]

, 2019
Background: This cluster randomised controlled trial set out to investigate the feasibility and acceptability of the “Combined Diabetes and Renal Control Trial” (C-DIRECT) intervention, a nurse-led intervention based on motivational interviewing and self-
AM Jacobson, AS Zigmond, AY Lai, C. G. Chua, CA Eigenmann, CSY Goh, DJ Toobert, E Salsberg, E. Y. H. Khoo, EA Bayliss, EA Beverly, EA Kerr, F Willingham, GW Welch, H Knight, H Vlaminck, I Bjelland, IM Stratton, IR White, JY Chen, K Griva, K. Griva, KR Lorig, L Bramley, M Anees, M. Nandakumar, M. Rajeswari, MA Powers, ME Charlson, MF Huang, MJ Davies, P Craig, R Schwarzer, RD Hays, RH Osborne, RK Yoong, S Newman, S. P. Newman, SL Norris, T Washington, V Braun, V. Y. W. Lee, WH Polonsky, Y-Q Huang, Y. T. D. Choong, YH Tang, Z. S. Goh   +46 more
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