What is an “ongoing” clinical trial? An analysis of different sources revealed heterogeneous definitions of when a clinical trial starts and ends: a meta-research study [PDF]
BACKGROUND: Although the concept of an “ongoing study” seems self-explanatory, it is difficult to determine whether a trial is underway. OBJECTIVE: To analyze the definitions of “ongoing clinical trial” across different clinical trial registries ...
Rafael Leite Pacheco +2 more
doaj +1 more source
Low-intensity extracorporeal shockwave therapy in the treatment of erectile dysfunction – a narrative review [PDF]
Objectives: To provide an overview of low-intensity extracorporeal shockwave therapy (LIEST) for erectile dysfunction (ED), pointing out which concepts are already consolidated and which paths we still need to advance.
Rodrigo R. Vieiralves +2 more
doaj +1 more source
The effect FRIENDS program on the anxiety of adolescent girls
Background: Anxiety is one of the most common psychological problems among adolescents which have been almost considered by researchers. In this regard, the present study was conducted to examine the effect of the FRIENDS training program on the anxiety ...
Gholamreza Sanagooe Moharer +3 more
doaj +1 more source
Studies sometimes aim to show that a new intervention is not substantially worse than the existing standard of care while offering some benefits, for example, lower cost, decreased toxicity, or easier administration.
Priya Ranganathan +2 more
doaj +1 more source
In an equivalence trial, researchers aim to show that a new intervention is more or less similar to an existing standard of care, i.e., the two are “equivalent”.
Priya Ranganathan +2 more
doaj +1 more source
Effect of L-carnitine on quality of life in covert hepatic encephalopathy: a randomized, double-blind, placebo-controlled study [PDF]
Background/Aims L-carnitine is potentially beneficial in patients with hepatic encephalopathy (HE). We aimed to evaluate the impact of L-carnitine on the quality of life and liver function in patients with liver cirrhosis and covert HE.
Eileen L. Yoon +13 more
doaj +1 more source
Interventions in hypertension: systematic review and meta-analysis of natural and quasi-experiments
Background Hypertension is an urgent public health problem. Consistent summary from natural and quasi-experiments employed to evaluate interventions that aim at preventing or controlling hypertension is lacking in the current literature.
Tong Xia, Fan Zhao, Roch A. Nianogo
doaj +1 more source
Visual data: a new tool to improve the presentation of clinical trial results
Randomized controlled trials are known to be the best tool to determine the effects of an intervention; however, most healthcare professionals are not able to adequately understand the results.
Raphael Mendes Ritti-Dias +2 more
doaj +2 more sources
INTRODUCTION: Open access publishing is becoming increasingly popular within the biomedical sciences. SciELO, the Scientific Electronic Library Online, is a digital library covering a selected collection of Brazilian scientific journals many of which ...
Raphael Freitas de Souza +3 more
doaj +1 more source
EVALUATION OF OUTCOMES IN INTERVENTION RANDOMIZED CLINICAL TRIALS - DISTAL RADIUS FRACTURES
Objectives: Describe the frequency and types of outcomes in randomized clinical trials (RCT) of intervention for distal radius fractures, analyze how confusing outcome presentations can lead to misinterpretations, and suggest strategies to improve the ...
Davi Amorim Meira +5 more
doaj +1 more source

