Results 11 to 20 of about 57,506,680 (308)

How necessary are randomized controlled trials? [PDF]

, 2012
Randomized controlled trials (RCTs) are often deemed the gold standard for testing new treatments. This belief in turn justifies recruiting patients into such trials even when it is suspected that a new treatment is superior – although patients in the ...
Northcott, Robert
core   +7 more sources

Topical vitamin D3: A randomized controlled trial (RCT) [PDF]

Clinical Nutrition ESPEN, 2018
The intent of this study was to test the effect of Top-D, a topical Vitamin D preparation, in delivering vitamin D.Five hundred and fifty healthy patients, with vitamin D insufficiency and deficiency were recruited after written informed consent. Demographic data was recorded, adequate history and clinical examination was done to rule out any metabolic
Dalal A, Bubshait, Dakheel A, Al-Dakheel, Fawaz M, Alanii   +2 more
openaire   +2 more sources

Efficacy of Topical Benzocaine in Maxilla: A Randomized Controlled Trial [PDF]

Anesthesia Progress, 2019
This study aims to compare the effect of topical anesthesia against the use of no topical agent on pain of needle penetration and local anesthesia deposition during buccal infiltration in anterior maxilla. In a randomized controlled trial, 100 adult participants were randomly allocated to the benzocaine group (received 20% benzocaine gel) and no ...
Nurain, Rehman, Samir Riaz, Qazi
openaire   +2 more sources

Topical Endoxifen for Mammographic Density Reduction—A Randomized Controlled Trial

The Oncologist, 2022
Abstract Although breast cancer incidence is increasing, there are few primary preventive initiatives. Tamoxifen can reduce breast cancer incidence but is rarely used for primary prevention due to adverse events and tolerance issues.
Magnus Bäcklund, Mikael Eriksson, Marike Gabrielson, Mattias Hammarström, Steve Quay, Jenny Bergqvist, Roxanna Hellgren, Kamila Czene, Per Hall   +8 more
openaire   +2 more sources

Effectiveness of Topic-specific Infobuttons: A Randomized Controlled Trial [PDF]

Journal of the American Medical Informatics Association, 2008
Infobuttons are decision support tools that provide links within electronic medical record systems to relevant content in online information resources. The aim of infobuttons is to help clinicians promptly meet their information needs. The objective of this study was to determine whether infobutton links that direct to specific content topics ("topic ...
Guilherme, Del Fiol, Peter J, Haug, James J, Cimino, Scott P, Narus, Chuck, Norlin, Joyce A, Mitchell   +5 more
openaire   +2 more sources

Topical tretinoin for treating photoaging: A systematic review of randomized controlled trials

International Journal of Women’s Dermatology, 2022
Background: Aging, an inevitable and continuous process in one’s lifetime, has all along been a focus of interest, especially for women, yet photoaging treatment to slow the process remains challenging. Recent studies have demonstrated the potency of topical tretinoin in the treatment of photoaging. Tretinoin, a
Irma Bernadette S. Sitohang, MD, PhD, Wresti Indriatmi Makes, MD, PhD, Normalina Sandora, MD, PhD, Jose Suryanegara, MD   +3 more
openaire   +3 more sources

Fecal incontinence: the quality of reported randomized, controlled trials in the last ten years. [PDF]

, 2008
This study was designed to analyze the characteristics and the quality of reporting of randomized, controlled trials published during the last ten years on fecal ...
Norton, C., Parés, D., Chelvanayagam, Sonya   +2 more
core   +1 more source

Systematic techniques for assisting recruitment to trials (START): study protocol for embedded, randomized controlled trials [PDF]

, 2014
Background Randomized controlled trials play a central role in evidence-based practice, but recruitment of participants, and retention of them once in the trial, is challenging.
Anne Kennedy, Shaun Treweek, Madurasinghe, Vichithranie, Wallace, P, David J. Collier, Paul Wallace, Kennedy, A, Bower, P; id_orcid, Peter Knapp, Treweek, S, Small, N; id_orcid, Bower, P, Eldridge, Sandra, Graffy, Jonathan, Graffy, J, David Torgerson, Wallace, Paul, Knapp, P, Nicola Small, Hughes-Morley, A, Salisbury, Chris, Treweek, Shaun, Eldridge, S, Chris Salisbury, Small, N, Torgerson, D, Peter Bower, Bower, Peter, Hughes-Morley, Adwoa, Madurasinghe, V, Knapp, Peter, Torgerson, David, Rick, J, Adwoa Hughes-Morley, Rick, Jo, Salisbury, C, Kennedy, Anne, Collier, DJ, Jonathan Graffy, Vichithranie Madurasinghe, Jo Rick, Collier, David J, Small, Nicola, Sandra Eldridge   +43 more
core   +2 more sources

Quality of the systematic reviews in cochrane multiple sclerosis related articles [PDF]

BioSocial Health Journal
Introduction: To enhance the assessment of the systematic reviews and meta-analyses performed by the Cochrane Multiple Sclerosis (MS) Group. Methods: Our study was conducted on 57 systematic reviews and meta-analyses related to MS, published by the ...
Masoud Zeynalzadeh, Nasim Mahdavi, Morteza Atayi, Hanieh Salehi-Pourmehr, Sakineh Hajebrahimi   +4 more
doaj   +1 more source

CONSORT for Reporting Randomized Controlled Trials in Journal and Conference Abstracts: Explanation and Elaboration [PDF]

, 2008
BACKGROUND: Clear, transparent, and sufficiently detailed abstracts of conferences and journal articles related to randomized controlled trials (RCTs) are important, because readers often base their assessment of a trial solely on information in the ...
Hopewell, S, Douglas G Altman, Moher, D., Mike Clarke, Schulz, KF, Hopewell, S., Wager, E., Philippa Middleton, The, CG, Sally Hopewell, Schulz, K., Moher, D, Altman, DG, CONSORT Group, Middleton, P, Clarke, M., Hopewel, S, Kenneth F Schulz, Elizabeth Wager, Wager, E, Middleton, P., Hopewell, Sally, David Moher, Altman, D., null null, Clarke, Michael, Haynes, B., Rennie, D., Gebski, V., Goodman, S., Ellenberg, S., Elbourne, D., Schriger, D., Altman, D.G., Grunberg, S., Devereaux, D.J., Montori, V.M., James, A., Pocock, S., Boutron, I., Diderot, D., Dickersin, K., Simera, I.Iveta, Juhn, P., Gøtzsche, P.C., Schulz, K.F., Groves, T., Babour, V., Mulro, C., Minckle, D., Berlin, J.   +50 more
core   +1 more source