Randomized controlled trial of topical phenylephrine in the treatment of faecal incontinence
Abstract Background Anal incontinence due to internal sphincter dysfunction is not amenable to simple surgical repair. The α-adrenergic agonist phenylephrine produces contraction of the internal sphincter and raises resting pressure when applied topically in healthy volunteers.
E A, Carapeti, M A, Kamm, R K, Phillips
openaire +2 more sources
Aim. In order to study the possibilities of aldosterone antagonists in the treatment of patients with acute myocardial infarction with ST elevation without chronic heart failure and post-MI chronic heart failure with low ejection fraction recent ...
V. V. Syvolap +4 more
doaj +1 more source
The incidence of delirium in intensive care patients remains high, and its consequences have a high negative impact on patients, their families, health care teams, and society in general.
Luz Omaira Gómez Tovar +1 more
doaj +1 more source
Comprehensive systematic review summary: Treatment of tics in people with Tourette syndrome and chronic tic disorders [PDF]
Objective To systematically evaluate the efficacy of treatments for tics and the risks associated with their use. Methods This project followed the methodologies outlined in the 2011 edition of the American Academy of Neurology\u27s guideline development
Cavanna, Andrea E +12 more
core +2 more sources
Parasacral Transcutaneous Electrical Nerve Stimulation with Desmopressin Acetate for Treating Primary Monosymptomatic Enuresis: A Randomized Controlled Clinical Trial [PDF]
Purpose: Approximately one-third of the children with primary monosymptomatic enuresis (PMNE) do not respond to first-line treatment. We aimed to investigate the short-term and six-month effectiveness of combining desmopressin acetate with parasacral ...
Melissa Faria Dutra +8 more
doaj +1 more source
The Effect of Schroth Therapy on Thoracic Kyphotic Curve and Quality of Life in Scheuermann’s Patients: A Randomized Controlled Trial [PDF]
Study Design Randomized controlled single-blinded clinical trial. Purpose To evaluate the efficacy of Schroth therapy on thoracic curve angle, pain, and self-perceived body image (SPBI) of the back in Scheuermann’s patients in comparison with the ...
Tomer Bezalel +3 more
doaj +1 more source
In 2014–2015, we conducted a randomized controlled trial (RCT) assessing the effect of an advertising campaign for influenza vaccination using posters and pamphlets in general practitioner (GP) waiting rooms.
Christophe Berkhout +7 more
doaj +1 more source
Aspirin and the Primary Prevention of Cardiovascular Diseases. An Approach Based on Individualized, Integrated Estimation of Risk [PDF]
While the use of aspirin in the secondary prevention of cardiovascular (CVD) is well established, aspirin in primary prevention is not systematically recommended because the absolute CV event reduction is similar to the absolute excess in major bleedings.
Battistoni, Allegra +4 more
core +1 more source
Darifenacin Versus Parasacral Transcutaneous Electric Nerve stimulation for overactive bladder syndrome in patients infected with Human T-Lymphotropic Virus 1 – randomized open clinical trial [PDF]
Purpose: To evaluate the efficacy of parasacral transcutaneous electric nerve stimulation (PTENS), in comparison to darifenacin for the reduction of OAB symptoms in patients infected with HTLV-1.
Tatiane Souza Soares de Oliveira +4 more
doaj +1 more source
Background: Participation in clinical trials is linked to improved patient outcomes. Despite this, most trial participants either reside in, or are treated in metropolitan areas.
Anne Woollett +10 more
doaj +1 more source

