Results 51 to 60 of about 188,812 (316)
Preoperative radiotherapy and curative surgery for the management of localised rectal carcinoma
Background: This is an update of the original review published in 2007. Carcinoma of the rectum is a common malignancy, especially in high income countries. Local recurrence may occur after surgery alone. Preoperative radiotherapy (PRT) has the potential
Valentini, Vincenzo
core +1 more source
Therapeutic alternatives in painful diabetic neuropathy: a meta-analysis of randomized controlled trials [PDF]
Background: One of the most frequent problems caused by diabetes is the so called painful diabetic neuropathy. This condition can be treated through numerous types of therapy.
Reina Bueno, María +9 more
core +1 more source
Only one meta-analysis has been published to discuss this topic and a good number of new trials have been published since then. The aim of this updated meta-analysis was to critically examine and evaluate the evidence of recent randomized controlled ...
Jinwei Guo
core +1 more source
Background Accurate reporting on sex and gender in health research is integral to ensuring that health interventions are safe and effective. In Canada and internationally, governments, research organizations, journal editors, and health agencies have ...
V. Welch +15 more
doaj +1 more source
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye +33 more
wiley +1 more source
Recommendations on recording harms in randomised controlled trials of behaviour change interventions [PDF]
Harms are possible from behaviour change interventions, such as the worsening of a health behaviour intended for change (rebound effect), improving a health behaviour but with subsequent worsening of another behaviour (risk compensation), and ...
Sprange, K. +11 more
core +1 more source
Estimates of the mean difference in orthopaedic randomized trials: obligatory yet obscure
Background Randomized controlled trials in orthopaedics are powered to mainly find large effect sizes. A possible discrepancy between the estimated and the real mean difference is a challenge for statistical inference based on p-values.
Lauri Raittio +3 more
doaj +1 more source
Oral versus topical tamoxifen in cyclical mastalgia—A randomized controlled trial
Mastalgia affects premenopausal in which cyclical mastalgia affects up to 40% of women. In approximately 8% of these women, pain will be severe and interfere with their normal activities. oral tamoxifen widely used in the treatment of mastalgia is associated with a wide range of side effects. Topical tamoxifen has the potential to be a more efficacious
Divya Dhananjay Singh +3 more
openaire +2 more sources
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Objective: We wish to update existing meta-analyses to assess the effectiveness of pharmacological agents against ureteral stent-related symptoms with better design of RCTs, as well as more valid and reliable measurement methods.
Andi As'ad Mubarak +3 more
doaj +1 more source

