Results 21 to 30 of about 43,824,661 (311)

CONSORT for Reporting Randomized Controlled Trials in Journal and Conference Abstracts: Explanation and Elaboration [PDF]

open access: yes, 2008
BACKGROUND: Clear, transparent, and sufficiently detailed abstracts of conferences and journal articles related to randomized controlled trials (RCTs) are important, because readers often base their assessment of a trial solely on information in the ...
Hopewell, S   +26 more
core   +1 more source

How necessary are randomized controlled trials? [PDF]

open access: yes, 2012
Randomized controlled trials (RCTs) are often deemed the gold standard for testing new treatments. This belief in turn justifies recruiting patients into such trials even when it is suspected that a new treatment is superior – although patients in the ...
Northcott, Robert
core   +2 more sources

Investigator initiated trials versus industry sponsored trials - translation of randomized controlled trials into clinical practice (IMPACT)

open access: yesBMC Medical Research Methodology, 2021
Background Healthcare decisions are ideally based on clinical trial results, published in study registries, as journal articles or summarized in secondary research articles.
Anette Blümle   +9 more
doaj   +1 more source

Randomized Controlled Trials on PET: A Systematic Review of Topics, Design, and Quality [PDF]

open access: yesJournal of Nuclear Medicine, 2012
Randomized controlled trials (RCTs) add important information to diagnostic accuracy studies in the evaluation of PET and PET/CT. We evaluated how many RCTs on PET existed, which clinical topics they addressed, and what their design and quality were.We searched MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials (Clinical Trials) up
Fülöp, Scheibler   +8 more
openaire   +2 more sources

Risk of bias analysis in diabetic retinopathy randomized clinical trials evaluated by RoB-1 tool from Cochrane systematic reviews

open access: yesJournal of Evidence-Based Healthcare, 2022
The objective of clinical trials is to answer about intervention in the real-world, for which they must be properly designed and executed by presenting the results reliably with the findings and in a clear way.
Vânia Mozetic   +3 more
doaj   +1 more source

Analysis of hospital and payer costs of care: aggressive warming versus routine warming in abdominal major surgery

open access: yesFrontiers in Public Health, 2023
BackgroundHypothermia is common and active warming is recommended in major surgery. The potential effect on hospitals and payer costs of aggressive warming to a core temperature target of 37°C is poorly understood.MethodsIn this sub-analysis of the ...
Shujia Song   +6 more
doaj   +1 more source

The Xylitol Applicability and its Effects in Health Area Worldwide: A Bibliometric Analysis Based on Randomized Controlled Trials

open access: yesPesquisa Brasileira em Odontopediatria e Clínica Integrada, 2022
Objective: To describe and evaluate the xylitol products’ applicability and its effects in the health area worldwide utilizing a bibliometric analysis from randomized controlled trials (RCT) with humans.
Mariana Leonel Martins   +7 more
doaj  

The external validity of published randomized controlled trials in primary care [PDF]

open access: yes, 2009
Background - A criticism of Randomized Controlled Trials (RCTs) in primary care is that they lack external validity, participants being unrepresentative of the wider population.
Jones Robert O   +29 more
core   +2 more sources

Analysis of the Cochrane Review: Incentives for Smoking Cessation. Cochrane Database Syst Rev. 2015;5:CD004307.

open access: yesActa Médica Portuguesa, 2016
Material incentives for alteration or reinforcement of healthy behaviours have been widely used in several health systems. These incentives, which are used in various contexts such as workplaces, health facilities or community programs, have been ...
António Vaz-Carneiro, João Costa
doaj   +1 more source

Randomized controlled trial of topical phenylephrine in the treatment of faecal incontinence

open access: yesJournal of British Surgery, 2000
Abstract Background Anal incontinence due to internal sphincter dysfunction is not amenable to simple surgical repair. The α-adrenergic agonist phenylephrine produces contraction of the internal sphincter and raises resting pressure when applied topically in healthy volunteers.
E A, Carapeti, M A, Kamm, R K, Phillips
openaire   +2 more sources

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