Results 1 to 10 of about 327,809 (311)

Cardiovascular Safety Signals of Oral Versus Topical Minoxidil in FAERS: A Disproportionality Analysis (Analytic Cohort 2012–2025) [PDF]

Life
Oral minoxidil, including low-dose regimens, is increasingly used off-label for alopecia, but cardiovascular safety remains a clinical concern. We compared cardiovascular adverse event reporting patterns for oral versus topical minoxidil using a ...
Hima Bindu Makkena, Vikas Kasu
doaj   +2 more sources

Acute Hyperglycemia Due to Topical Corticosteroid Administration

Case Reports in Endocrinology, 2019
We present the case of a 71-year-old man with longstanding, previously well-controlled type 1 diabetes who developed acute hyperglycemia. His insulin requirements, via his insulin pump, increased to nearly five times his typical daily dose.
Laura Y. Sue, Anna Milanesi
doaj   +5 more sources

Effectiveness of tranexamic acid in intervening postpartum vaginal lacerations [PDF]

BMC Pregnancy and Childbirth
Aims This prospective randomized controlled study aimed to investigate the effectiveness of tranexamic acid in controlling bleeding due to postpartum vaginal lacerations and to compare the intravenous (IV) and topical routes of administration.
Omer Tammo, Emre Uysal
doaj   +2 more sources

Topical timolol for superficial cutaneous infantile hemangiomas in very preterm infants [PDF]

Vojnosanitetski Pregled, 2021
Introduction. Infantile hemangiomas (IHs) occur 3 to 4 times more frequently in preterm infants than in those born at term. Yet, data about efficacy and safety of topical therapy for IHs in preterm infants, especially in those born with very low ...
Matić Aleksandra, Prćić Sonja, Matić Milan   +2 more
doaj   +1 more source

A promising alternative for mature skin: the effects of phytoestrogens on human skin and its topical use [PDF]

Revista Brasileira de Cirurgia Plástica, 2023
Skin quality deteriorates with age for various reasons, including hormone deficiencies. In women, the decline in estrogen levels during menopause plays an important role in skin degeneration, with consequent atrophy, collagen reduction, loss of ...
Júnia Lira Carneiro, Alessandra Haddad, Iago Bretas Righi, Lydia Masako Ferreira   +3 more
doaj   +1 more source

Graphene Oxide Topical Administration: Skin Permeability Studies [PDF]

Materials, 2021
Nanostructured carriers have been widely used in pharmaceutical formulations for dermatological treatment. They offer targeted drug delivery, sustained release, improved biostability, and low toxicity, usually presenting advantages over conventional formulations. Due to its large surface area, small size and photothermal properties, graphene oxide (GO)
Filipa A. L. S. Silva, Raquel Costa-Almeida, Licínia Timochenco, Sara I. Amaral, Soraia Pinto, Inês C. Gonçalves, José R. Fernandes, Fernão D. Magalhães, Bruno Sarmento, Artur M. Pinto   +9 more
openaire   +3 more sources

Hyaluronic acid: perspectives in upper aero-digestive tract. A systematic review [PDF]

, 2015
Background: To date, topical therapies guarantee a better delivery of high concentrations of pharmacologic agents to the mucosa of the upper aerodigestive tract (UADT).
Baptista, Peter, Casale, Manuele, Moffa, Antonio, Oliveto, Giuseppe, Pace, Annalisa, Sabatino, Lorenzo, Salvinelli, Fabrizio, Vitali, Massimiliano   +7 more
core   +10 more sources

Delivery of biologics: Topical administration

Biomaterials, 2023
Biologics are unaffordable to a large majority of the global population because of prohibitively expensive fermentation systems, purification and the requirement for cold chain for storage and transportation. Limitations of current production and delivery systems of biologics were evident during the recent pandemic when 90% are delivered using invasive
Rachel J. Kulchar, Rahul Singh, Suwan Ding, Elena Alexander, Kam W. Leong, Henry Daniell   +5 more
openaire   +4 more sources

Cryoanesthesia with ethyl chloride spray versus 5% lidocaine gel in alleviating oral local anesthetic injection pain for buccal anaesthesia: A randomized clinical (controlled) trial [PDF]

Journal of Dental Research, Dental Clinics, Dental Prospects, 2023
Background. Numbing the area of oral mucosa with cold application prior to administration of regional anesthesia has been widely used by various dentists in alleviating pain caused by needle prick.
Hira Abbasi, Faiza Ali, Hina Aslam, Muhammad Sharjeel Khan, Muhammad Waqas, Abhishek Lal   +5 more
doaj   +1 more source

Topical (S)-ketamine for pain management of postherpetic neuralgia [PDF]

Anais Brasileiros de Dermatologia, 2012
Herpes zoster infection may cause postherpetic neuralgia, which is defined by prolonged pain predominantly mediated by central nervous system hypersensitivity.
Guilherme Antonio Moreira de Barros, Hélio Amante Miot, Ademir Massarico Braz, Flávia Ramos, Marcos Aristoteles Borges   +4 more
doaj   +1 more source