Delivery of biologics: Topical administration [PDF]
Biologics are unaffordable to a large majority of the global population because of prohibitively expensive fermentation systems, purification and the requirement for cold chain for storage and transportation. Limitations of current production and delivery systems of biologics were evident during the recent pandemic when 90% are delivered using invasive
Rachel J. Kulchar +5 more
openaire +5 more sources
Xerostomia is linked to an increased risk of dental caries, oral fungal infections, and speaking/swallowing difficulties, factors that may significantly degrade patients’ life, socially- or emotionally-wise.
Afroditi Kapourani +2 more
doaj +3 more sources
The use of topical diclofenac in the pain management of osteoarthritis of the knee [PDF]
Osteoarthritis (OA) is a common complaint that affects millions of people worldwide. As there is no cure for OA, drug treatment is the main form of management.
Banning, M
core +6 more sources
Acute Hyperglycemia Due to Topical Corticosteroid Administration
We present the case of a 71-year-old man with longstanding, previously well-controlled type 1 diabetes who developed acute hyperglycemia. His insulin requirements, via his insulin pump, increased to nearly five times his typical daily dose.
Laura Y. Sue, Anna Milanesi
doaj +5 more sources
Nanostructured Lipid Carriers Enriched Hydrogels for Skin Topical Administration of Quercetin and Omega-3 Fatty Acid [PDF]
Lopes C M +2 more
exaly +2 more sources
Cryoanesthesia with ethyl chloride spray versus 5% lidocaine gel in alleviating oral local anesthetic injection pain for buccal anaesthesia: A randomized clinical (controlled) trial [PDF]
Background. Numbing the area of oral mucosa with cold application prior to administration of regional anesthesia has been widely used by various dentists in alleviating pain caused by needle prick.
Hira Abbasi +5 more
doaj +1 more source
Evidence of Cannabidiol Effectiveness Associated or Not with Tetrahydrocannabinol in Topical Administration: A Scope Review [PDF]
Ana Laura Masquetti Fava +2 more
exaly +2 more sources
Recent advances in topical therapeutics for vitreoretinal diseases [PDF]
Eye drops are convenient for patients, but achieving therapeutic doses and maintaining sustained drug release without frequent re-application to treat diseases of the retina has been largely unsuccessful.
Gibson, Jonathan, McGinnigle, Samantha
core +8 more sources
Silk peptide-hyaluronic acid based nanogels for the enhancement of the topical administration of curcumin [PDF]
Huiyuan Ya, Yanli Fan
exaly +2 more sources
Topical (S)-ketamine for pain management of postherpetic neuralgia [PDF]
Herpes zoster infection may cause postherpetic neuralgia, which is defined by prolonged pain predominantly mediated by central nervous system hypersensitivity.
Guilherme Antonio Moreira de Barros +4 more
doaj +1 more source

