Results 1 to 10 of about 311,236 (170)

“There’s Not Enough Bodies to Do the Demand:” An Exploration of Key Stakeholder Views on the Role of Health Service Capacity in Shaping Cancer Outcomes in 7 International Cancer Benchmarking Partnership Countries [PDF]

International Journal of Health Policy and Management, 2022
BackgroundDifferences in cancer survival are shaped by differences in health system capacity in workforce and infrastructure. Part of the International Cancer Benchmarking Partnership (ICBP), this study explored stakeholders’ perceptions of the role of ...
Maureen Seguin, Melanie Morris, Martin McKee, Ellen Nolte   +3 more
doaj   +1 more source

Combining network pharmacology, molecular docking, molecular dynamics simulation, and experimental verification to examine the efficacy and immunoregulation mechanism of FHB granules on vitiligo

Frontiers in Immunology, 2023
BackgroundFufang Honghua Buji (FHB) granules, have proven efficacy against vitiligo in long-term clinical practice. However, its major active chemical components and molecular mechanisms of action remain unknown.
Xiaolong Li, Xiaolong Li, Fengze Miao, Fengze Miao, Rujuan Xin, Rujuan Xin, Zongguang Tai, Zongguang Tai, Huijun Pan, Huijun Pan, Hao Huang, Hao Huang, Junxia Yu, Junxia Yu, Zhongjian Chen, Zhongjian Chen, Quangang Zhu, Quangang Zhu   +17 more
doaj   +1 more source

Skin permeation and penetration of mometasone furoate in the presence of emollients: An ex vivo evaluation of clinical application protocols

Skin Health and Disease, 2023
Background Topical corticosteroids (TCS) and emollients are developed independently by the pharmaceutical industry but are often used together in practice.
Mubinah T. Beebeejaun, Marc B. Brown, Victoria Hutter, Laura Kravitz, William J. McAuley   +4 more
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Effect and mechanism of longkui yinxiao soup in treating psoriasis in mice

Frontiers in Pharmacology, 2023
Objective: Longkui Yinxiao Soup is a traditional Chinese medicine formula used to treat psoriasis for decades. Although Longkui Yinxiao Soup showed promising efficacy in clinical practice, the regulatory mechanisms of Longkui Yinxiao Soup remain elusive.
Congcong Zhu, Congcong Zhu, Ya Chen, Ya Chen, Zongguang Tai, Zongguang Tai, Huijun Pan, Huijun Pan, Min Shen, Min Shen, Zhongjian Chen, Zhongjian Chen, Quangang Zhu, Quangang Zhu   +13 more
doaj   +1 more source

Reduced skin permeation and penetration of clobetasol propionate when Dermovate cream is applied at short time intervals with emollients

JEADV Clinical Practice, 2023
Background Dermovate cream containing 0.05% clobetasol propionate is a very potent topical corticosteroid (TCS) used in the treatment of severe inflammatory dermatoses.
M. T. Beebeejaun, M. B. Brown, V. Hutter, L. Kravitz, W. J. McAuley   +4 more
doaj   +1 more source

Topic Models with Topic Ordering Regularities for Topic Segmentation [PDF]

2014 IEEE International Conference on Data Mining, 2014
Documents from the same domain usually discuss similar topics in a similar order. In this paper we present new ordering-based topic models that use generalised Mallows models to capture this regularity to constrain topic assignments. Specifically, these new models assume that there is a canonical topic ordering shared amongst documents from the same ...
Lan Du 0002, John K. Pate, Mark Johnson 0001   +2 more
openaire   +1 more source

Mapping topics and topic bursts in PNAS [PDF]

Proceedings of the National Academy of Sciences, 2004
Scientific research is highly dynamic. New areas of science continually evolve; others gain or lose importance, merge, or split. Due to the steady increase in the number of scientific publications, it is hard to keep an overview of the structure and dynamic development of one's own field of science, much less all scientific domains.
Ketan K. Mane, Katy Börner
openaire   +3 more sources

High Content Image Analysis as a Tool to Morphologically Distinguish Macrophage Activation and Determine Its Importance for Foamy Alveolar Macrophage Responses

Frontiers in Immunology, 2021
IntroductionLung diseases are an increasing global health burden affecting millions of people worldwide. Only a few new inhaled medicines have reached the market in the last 30 years, in part due to foamy alveolar macrophage (FAM) responses observed in ...
Ewelina Hoffman, Paulina Napieralska, Rhamiya Mahendran, Darragh Murnane, Victoria Hutter   +4 more
doaj   +1 more source

Epidermal Delivery of Retinyl Palmitate Loaded Transfersomes: Penetration and Biodistribution Studies

Pharmaceutics, 2020
The alteration of retinoids levels in the skin can cause different disorders in the maturation of epithelial skin cells. Topical administration of these lipophilic molecules is a challenge that can be addressed by encapsulation into drug delivery systems.
Eloy Pena-Rodríguez, Mari Carmen Moreno, Bárbara Blanco-Fernandez, Jordi González, Francisco Fernández-Campos   +4 more
doaj   +1 more source

A child with debilitating pruritus

Clinics and Practice, 2016
We describe a case of two-year-old boy presenting with debilitating pruritus, patchy alopecia and jaundice since the age of 6 months. On evaluation he had intrahepatic cholestasis with persistently raised serum alkaline phosphatase, normal Gamma glutamyl
Nikhil Sonthalia, Sami S. Jain, Vinay B. Pawar, Vinay G. Zanwar, Ravindra G. Surude, Pravin M. Rathi, Kshitij K. Munde, Sandeep Bavdekar   +7 more
doaj   +1 more source