Results 41 to 50 of about 882,555 (308)

The International Workshop on Wave Hindcasting and Forecasting and the Coastal Hazards Symposium

, 2015
Following the 13th International Workshop on Wave Hindcasting and Forecasting and 4th Coastal Hazards Symposium in October 2013 in Banff, Canada, a topical collection has appeared in recent issues of Ocean Dynamics.
Babanin, Alexander, Breivik, Øyvind, Horsburgh, Kevin, Swail, Val   +3 more
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Mechanisms and active components of Solanum nigrum in the amelioration of psoriatic lesions

Frontiers in Immunology
IntroductionPsoriasis is a prevalent chronic inflammatory skin disease in which pattern recognition receptors, particularly the NLRP3 inflammasome, are increasingly implicated in disease pathogenesis.
Ya Chen, Ya Chen, Tianyou Ma, Tianyou Ma, Congcong Zhu, Congcong Zhu, Zongguang Tai, Zongguang Tai, Huijun Pan, Huijun Pan, Zhongjian Chen, Zhongjian Chen, Quangang Zhu, Quangang Zhu   +13 more
doaj   +1 more source

Topical analgesia for acute otitis media [PDF]

, 2006
BACKGROUND: Acute otitis media (AOM) is a spontaneously remitting disease for which pain is the most distressing symptom. Antibiotics are now known to have less benefit than previously assumed.OBJECTIVES: To assess the effectiveness of topical analgesia ...
Del Mar, C, Dooley, L, Foxlee, R, Johansson, A, Wejfalk, J   +4 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Topical non-steroidal immunomodulators in dermatology

Indian Dermatology Online Journal, 2023
Immunological abnormality is the pathological basis of many dermatological disorders. Although steroids are the backbone of topical therapy in dermatology, the side effects are encountered quite frequently.
Priya P Kadu
doaj   +1 more source

The physics of neutron stars

, 2010
Topical problems in the physics of and basic facts about neutron stars are reviewed. The observational manifestations of neutron stars, their core and envelope structure, magnetic fields, thermal evolution, and masses and radii are briefly discussed ...
Potekhin, A. Y.
core   +1 more source

Localization of dexamethasone within dendritic core-multishell (CMS) nanoparticles and skin penetration properties studied by multi-frequency electron paramagnetic resonance (EPR) spectroscopy [PDF]

, 2016
The skin and especially the stratum corneum (SC) act as a barrier and protect epidermal cells and thus the whole body against xenobiotica of the external environment. Topical skin treatment requires an efficient drug delivery system (DDS).
Anske, M., Bittl, R., Fleige, E., Haag, R., Lohan, S.B., Meinke, M.C., Saeidpour, S., Teutloff, C., Unbehauen, M.   +8 more
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Interventions in cytokine signaling: novel horizons for psoriasis treatment

Frontiers in Immunology
Intricate interactions between immune cells and cytokines define psoriasis, a chronic inflammatory skin condition that is immunological-mediated. Cytokines, including interleukins (ILs), interferons (IFNs), tumor necrosis factors (TNFs), chemokines, and ...
Lisha Li, Lisha Li, Lisha Li, Jun Liu, Jun Liu, Jiaye Lu, Jiaye Lu, Junchao Wu, Junchao Wu, Xinyue Zhang, Xinyue Zhang, Tianyou Ma, Tianyou Ma, Xiying Wu, Xiying Wu, Quangang Zhu, Quangang Zhu, Zhongjian Chen, Zhongjian Chen, Zongguang Tai, Zongguang Tai   +20 more
doaj   +1 more source