Results 1 to 10 of about 1,912,056 (267)

Dynamic shifts in chromatin states differentially mark the proliferative basal cells and terminally differentiated cells of the developing epidermis

Epigenetics, 2020
Post-translational modifications on nucleosomal histones represent a key epigenetic regulatory mechanism to mediate the complex gene expression, DNA replication, and cell cycle changes that occur in embryonic cells undergoing lineage specification ...
Yan Ting Shue, Kang Ting Lee, Benjamin William Walters, Hui Binn Ong, Shaktheeshwari Silvaraju, Wei Jun Lam, Chin Yan Lim   +6 more
doaj   +1 more source

Reactive Epidermal Hyperplasia and Angiogenesis of the Rear (REAR): A Proposed Unifying Name for Senile Gluteal Dermatosis and Prurigiform Angiomatosis

Dermatopathology, 2022
Senile gluteal dermatosis (SGD) is a common but seldom recognized condition. It is characterized clinically by unilateral or bilateral hyperkeratotic, lichenified plaques on the gluteal area, being attributed to prolonged sitting, particularly in the ...
Michelle Weiting Liang, Joel H. L. Lim, Hui Yi Chia, Shang-Ian Tee, Joyce S. S. Lee   +4 more
doaj   +1 more source

Narrowband UVB-induced lichen planus pemphigoides

Dermatology Reports, 2011
Lichen planus pemphigoides (LPP) is an autoimmune disease characterised by evolution of subepidermal blisters on normal and lichen planus affected skin. We describe a case of LPP in a 54-year-old Chinese woman.
Wai Man Mandy Chan, Joyce Siong See Lee, Colin Seng Thiam Theng, Sze Hon Chua, Hazel Hwee Boon Oon   +4 more
doaj   +1 more source

Reconstruction of retroauricolar surgical defect using the "Jigsaw puzzle" advancement flap

Dermatology Reports, 2023
We present the case of a 55 years old male patient who came to our attention because of a basal cell carcinoma of the right retroauricolar area, near the mastoid-auricle border. The tumour had a size of about 1,5 cm.
Michela Curzio, Vittorio Macchini, Giovanni Di Lella, Antonio Massaro, Giulio Sonego   +4 more
doaj   +1 more source

Laser capture microdissection as a method for investigating the human hair follicle microbiome reveals region-specific differences in the bacteriome profile

BMC Research Notes, 2023
Objective Human hair follicles (HFs) are populated by a rich and diverse microbiome, traditionally evaluated by methods that inadvertently sample the skin microbiome and/or miss microbiota located in deeper HF regions.
Marta B. Lousada, J Edelkamp, T Lachnit, M Fehrholz, F Jimenez, R Paus   +5 more
doaj   +1 more source

Sirtuins in Skin and Skin Cancers [PDF]

Skin Pharmacology and Physiology, 2017
The sirtuins are a family of proteins that comprise class III of the histone deacetylases. These NAD+-dependent proteins have been found to be intricately involved in a variety of important and skin-relevant cellular functions and processes, including aging, UV damage response, oxidative stress, and wound repair.
Liz Mariely, Garcia-Peterson, Melissa Jean, Wilking-Busch, Mary Ann, Ndiaye, Christine Gaby Azer, Philippe, Vijayasaradhi, Setaluri, Nihal, Ahmad   +5 more
openaire   +2 more sources

Lycorine transfersomes modified with cell-penetrating peptides for topical treatment of cutaneous squamous cell carcinoma

Journal of Nanobiotechnology, 2023
Background Topical anticancer drugs offer a potential therapeutic modality with high compliance for treating cutaneous squamous cell carcinoma (cSCC). However, the existing topical treatments for cSCC are associated with limited penetrating ability to ...
Ying Li, Zongguang Tai, Jinyuan Ma, Fengze Miao, Rujuan Xin, Cuie Shen, Min Shen, Quangang Zhu, Zhongjian Chen   +8 more
doaj   +1 more source

β‐Lactam allergy testing and delabeling—Experiences and lessons from Singapore

Immunity, Inflammation and Disease, 2020
Background β‐Lactam allergy is over‐reported and this leads to greater healthcare costs. Allergy testing has inherent risks, yet patients who test negative may continue avoiding β‐lactams.
Yee Kiat Heng, Yasmin Chia Chia Liew, Yan Ling Kong, Yen Loo Lim   +3 more
doaj   +1 more source

Development of a Rapid and Confirmatory Method to Identify Ganoderic Acids in Ganoderma Mushrooms

Frontiers in Pharmacology, 2012
To examine the composition of lanostanoids in Ganoderma lucidum, we have developed a liquid chromatography-mass spectrometry (LC-MS) method by using the ganoderic acids isolated in our laboratory as reference standards.
Hao Howard Sun, Ying eQi, Lingling eZhao
doaj   +1 more source

Patient satisfaction with specialty internet hospital services in Shanghai: an analysis based on a five-dimensional service quality model

Critical Public Health
Objective To evaluate patient satisfaction with Shanghai’s specialty internet hospitals, this study identifies key drivers, priority areas for improvement, and actionable recommendations.Methods Patients with online consultations from June 2023 to June ...
Peng Hu, Wen-Jie Lu, Yu-Xi Qian, Jia-Min Shi, Fang Chen, Xue-Bing Jiang, Yan-Ting Wang   +6 more
doaj   +1 more source