Results 21 to 30 of about 2,110,949 (286)

Topical diclofenac: Clinical effectiveness and current uses in osteoarthritis of the knee and soft tissue injuries [PDF]

open access: yes, 2008
Background: Diclofenac is a commonly used non-steroidal anti-inflammatory drug (NSAID) for symptom control in osteoarthritis (OA) of the knee and soft tissue injuries.
Banning, M
core   +1 more source

Topical Ocular Administration of Progesterone Decreases Photoreceptor Cell Death in Retinal Degeneration Slow (rds) Mice

open access: yesPharmaceuticals, 2022
Retinitis pigmentosa (RP) is an inherited eye disorder which triggers a cascade of retinal disorders leading to photoreceptor cell death and for which there is currently no effective treatment.
Adrián M. Alambiaga-Caravaca   +4 more
doaj   +1 more source

Effects of Combined Intralesional 5-Fluorouracil and Topical Silicone in Prevention of Keloids: A Double Blind Randomized Clinical Trial Study [PDF]

open access: yesActa Medica Iranica, 2011
Keloids are aesthetically disfiguring and severely disabling. The optimal treatment remains undefined. This clinical study, evaluate the efficacy and side effects of combined topical silicone and 5-Fluorouracil on the prevention of keloids.
Hamid Reza Ghafarian Shirazi   +3 more
doaj   +2 more sources

A Novel Model of Pain Sensation Using Superfused Gastrosplenic Omentum Preparation of Anesthetized Rats

open access: yesJournal of Pharmacological Sciences, 2008
A pain model for screening analgesics was established in anesthetized rats. The omenta of urethane-anesthetized rats were exteriorized, fixed in a plastic chamber, and superfused with Tyrode solution.
Shi-Jie Yang   +2 more
doaj   +1 more source

Topical prostaglandin analogues and conjunctival inflammation in uveitic glaucoma. [PDF]

open access: yes, 2012
20.02.14 KB. Ok to add published verson to spiral, OA paper.A pilot study to determine whether topical prostaglandin analogues alter the expression of conjunctival inflammatory markers in patients with uveitic glaucoma.Prospective, single-masked case ...
Sallam, A   +3 more
core   +1 more source

Ice versus lidocaine 5% gel for topical anaesthesia of oral mucosa – a randomized cross-over study

open access: yesBMC Anesthesiology, 2019
Background Topical anaesthesia is important to optimize pain control during dental injection. Our aim was to describe a new simple method for topical anaesthesia of oral mucosa and to compare the effectiveness of ice and lidocaine 5% gel for topical ...
Nishma Hindocha   +3 more
doaj   +1 more source

In Vivo Evaluation of Cefuroxime Axetil-Loaded Bioadhesive Nanoparticles to Treat Haemophilus influenzae-Induced Otitis Media

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Otitis media (OM) is a common disease in children. One of the most common pathogens causing OM is non-typeable Haemophilus influenzae (NTHi). NTHi in the middle ear can be successfully eradicated by a regimen of oral antibiotics sustained for 7–10 days ...
Hong Lin   +6 more
doaj   +1 more source

Activity of different desoximetasone preparations compared to other topical corticosteroids in the vasoconstriction assay [PDF]

open access: yes, 2008
Introduction: We report on a double-blind, vehicle-controlled, single-center confirmatory study with random assignment. The purpose of the study was to investigate the topical bioavailability of different topical corticosteroid formulations in healthy ...
Borelli, Claudia   +5 more
core   +1 more source

Comparison of topical and intravenous tranexamic acid for reducing postoperative blood loss in single-level posterior lumbar interbody fusion: a retrospective study from Japan [PDF]

open access: yesAsian Spine Journal
Study Design A retrospective cohort study. Purpose This study aimed to compare the efficacy and safety of topical and relatively high-dose intravenous tranexamic acid (TXA) in minimizing postoperative blood loss in patients undergoing single-level ...
Kazuma Kitaguchi   +4 more
doaj   +1 more source

Polymeric Biomaterials for Topical Drug Delivery in the Oral Cavity: Advances on Devices and Manufacturing Technologies

open access: yesPharmaceutics, 2022
There are several routes of drug administration, and each one has advantages and limitations. In the case of the topical application in the oral cavity, comprising the buccal, sublingual, palatal, and gingival regions, the advantage is that it is ...
Paula de Freitas Rosa Remiro   +5 more
doaj   +1 more source

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