Results 21 to 30 of about 139,815 (216)

Protective Effects of Topical Administration of Laminarin in Oxazolone-Induced Atopic Dermatitis-like Skin Lesions

Marine Drugs, 2022
Laminarin is a polysaccharide isolated from brown marine algae and has a wide range of bioactivities, including immunoregulatory and anti-inflammatory properties. However, the effects of laminarin on atopic dermatitis have not been demonstrated.
Tae-Kyeong Lee, Dae Won Kim, Ji Hyeon Ahn, Choong-Hyun Lee, Jae-Chul Lee, Soon Sung Lim, Il Jun Kang, Seongkweon Hong, Soo Young Choi, Moo-Ho Won, Joon Ha Park   +10 more
doaj   +1 more source

Topical ophthalmic atropine in horses, pharmacokinetics and effect on intestinal motility

BMC Veterinary Research, 2021
Background Topical ophthalmic atropine sulfate is an important part of the treatment protocol in equine uveitis. Frequent administration of topical atropine may cause decreased intestinal motility and colic in horses due to systemic exposure.
L. Ström, F. Dalin, M. Domberg, C. Stenlund, U. Bondesson, M. Hedeland, P-L Toutain, C. Ekstrand   +7 more
doaj   +1 more source

TOPICAL NONSTEROID ANTI-INFLAMATORY DRUGS – INDICATIONS, EFFICACY AND SAFETY [PDF]

Romanian Journal of Rheumatology, 2019
Topical Nonsteroid anti-inflammatory drugs are efficient for the treatment of acute and chronic pain in musculo-skeletal diseases. There clinical benefit is similar to the oral form of administration, but with significant less systemic adverse events ...
Diana Mazilu, Ruxandra Ionescu
doaj   +1 more source

Plasma pharmacokinetics of tigolaner, emodepside, and praziquantel following topical administration of a combination product (Felpreva®) and of intravenous administration of the individual active ingredients in cats

Current Research in Parasitology and Vector-Borne Diseases, 2023
Felpreva® for cats contains the new acaricidal/insecticidal active ingredient tigolaner in a fixed combination with the nematocidal and cestocidal compounds emodepside and praziquantel, respectively.
Norbert Mencke, Wolfgang Bäumer, Kristine Fraatz, Ralph Krebber, Marc Schneider, Katrin Blazejak   +5 more
doaj   +1 more source

Study of bases influence on the biopharmaceutical characteristics of the pastes for onychomycosis therapy

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2018
According to the European and American authors the onychomycosis prevalence in the world has amount from 8.0 % to 26.9 %. Topical treatment of onychomycosis in most cases is the only acceptable method of therapy mainly due to high safety.
V. V. Luc, V. V. Gladyshev, A.P. Lisyanskaya, A.D. Diudiun   +3 more
doaj   +1 more source

Systemic and topical administration of spermidine accelerates skin wound healing

Cell Communication and Signaling, 2021
Background The skin wound healing process is regulated by various cytokines, chemokines, and growth factors. Recent reports have demonstrated that spermine/spermidine (SPD) promote wound healing through urokinase-type plasminogen activator (uPA)/uPA ...
Daisuke Ito, Hiroyasu Ito, Takayasu Ideta, Ayumu Kanbe, Soranobu Ninomiya, Masahito Shimizu   +5 more
doaj   +1 more source

Bisphosphonate: Brief Review of Its Development for Usage in Dentistry

Journal of Dentistry Indonesia, 2013
Bisphosphonate (BP) is a class of drug that prevent the loss of bone mass. It inhibits the resorption of bone by encouraging osteoclast to undergo apoptosis.
Tita Ratya Utari
doaj   +1 more source

Effects of Combined Intralesional 5-Fluorouracil and Topical Silicone in Prevention of Keloids: A Double Blind Randomized Clinical Trial Study [PDF]

Acta Medica Iranica, 2011
Keloids are aesthetically disfiguring and severely disabling. The optimal treatment remains undefined. This clinical study, evaluate the efficacy and side effects of combined topical silicone and 5-Fluorouracil on the prevention of keloids.
Hamid Reza Ghafarian Shirazi, Mohsen Hatamipour, Ebrahim Hatamipour, Saadat Mehrabi   +3 more
doaj   +2 more sources

Comparison of topical and intravenous tranexamic acid for reducing postoperative blood loss in single-level posterior lumbar interbody fusion: a retrospective study from Japan [PDF]

Asian Spine Journal
Study Design A retrospective cohort study. Purpose This study aimed to compare the efficacy and safety of topical and relatively high-dose intravenous tranexamic acid (TXA) in minimizing postoperative blood loss in patients undergoing single-level ...
Kazuma Kitaguchi, Kunihiko Hashimoto, Takashi Kaito, Kazuya Oshima, Eiji Wada   +4 more
doaj   +1 more source

Clinical Efficacy and Safety of Lidocaine Tape for Topical Anesthesia of the Oral Mucosa: A Preliminary Controlled Trial

Dentistry Journal, 2023
Local anesthesia is administered to reduce pain-induced stress during dental treatment. However, local anesthetic injections are extremely painful; thus, methods to minimize this pain should be developed. Clinical studies on the pain-relieving effects of
Ryouji Tani, Sachiko Yamasaki, Atsuko Hamada, Mirai Higaki, Yasuyuki Asada, Souichi Yanamoto   +5 more
doaj   +1 more source