Microneedles enhance the efficacy of topical dental anesthesia in male subjects: a randomized controlled trial [PDF]
: This study aimed to determine whether microneedles (MN) can enhance the efficacy of a commercially available topical anesthetic (EMLA®) when applied to the palatal mucosa.
Stephany Di Carla Santos +5 more
doaj +3 more sources
Comparative study on the wound healing effects of local versus systemic application of Polymyxin B in mice infected with multidrug-resistant Pseudomonas aeruginosa [PDF]
BackgroundWound infections caused by extensively drug-resistant Pseudomonas aeruginosa (XDR-PA) pose a significant clinical challenge with extremely limited treatment options. Polymyxin B (PMB) represents one of the last therapeutic lines of defence, yet
Chenhu Ma +6 more
doaj +2 more sources
Topical timolol for superficial cutaneous infantile hemangiomas in very preterm infants [PDF]
Introduction. Infantile hemangiomas (IHs) occur 3 to 4 times more frequently in preterm infants than in those born at term. Yet, data about efficacy and safety of topical therapy for IHs in preterm infants, especially in those born with very low ...
Matić Aleksandra +2 more
doaj +1 more source
A promising alternative for mature skin: the effects of phytoestrogens on human skin and its topical use [PDF]
Skin quality deteriorates with age for various reasons, including hormone deficiencies. In women, the decline in estrogen levels during menopause plays an important role in skin degeneration, with consequent atrophy, collagen reduction, loss of ...
Júnia Lira Carneiro +3 more
doaj +1 more source
Topical (S)-ketamine for pain management of postherpetic neuralgia [PDF]
Herpes zoster infection may cause postherpetic neuralgia, which is defined by prolonged pain predominantly mediated by central nervous system hypersensitivity.
Guilherme Antonio Moreira de Barros +4 more
doaj +1 more source
Xerostomia is linked to an increased risk of dental caries, oral fungal infections, and speaking/swallowing difficulties, factors that may significantly degrade patients’ life, socially- or emotionally-wise.
Afroditi Kapourani +2 more
doaj +1 more source
Cryoanesthesia with ethyl chloride spray versus 5% lidocaine gel in alleviating oral local anesthetic injection pain for buccal anaesthesia: A randomized clinical (controlled) trial [PDF]
Background. Numbing the area of oral mucosa with cold application prior to administration of regional anesthesia has been widely used by various dentists in alleviating pain caused by needle prick.
Hira Abbasi +5 more
doaj +1 more source
Effects of Rusanda Spa balneotherapy combined with calcipotriol on plaque psoriasis [PDF]
Background/Aim. Treatment of psoriasis is very complex and there are no still universal, nor unique treatment modalities. Apart from conventional treatment, which includes topical calcipotriol (vitamin D3 analogue), balneotherapy is drawing ...
Golušin Zoran +5 more
doaj +1 more source
Topical ocular delivery of nanoparticles with epoetin beta in Wistar Hannover rats
Topical instillation of drugs targeting the posterior ocular segment is an expanding area of research. Chitosan and hyaluronic acid have remarkable mucoadhesive properties and potentially enhance pre-corneal retention time after topical instillation ...
Beatriz Silva +3 more
doaj +1 more source
A case of successful removal of a zipper entrapped on the upper eyelid of a child using a lidocaine gel [PDF]
Zipper entrapment injuries require a technique to safely and promptly release the entrapped tissues to prevent complications. Herein, we report an 8-year-old girl whose eyelid was successfully released from an entrapping zipper.
So Yeon Choi, Soyun Hwang
doaj +1 more source

