Drug Stability Analysis by Raman Spectroscopy [PDF]
Pharmaceutics, 2014 Pharmaceutical drugs are available to astronauts to help them overcome the deleterious effects of weightlessness, sickness and injuries. Unfortunately, recent studies have shown that some of the drugs currently used may degrade more rapidly in space ...
Chetan Shende +3 more
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Cyclodextrins and Their Derivatives as Drug Stability Modifiers. [PDF]
Pharmaceuticals (Basel), 2023 Cyclodextrins (CDs) are cyclic oligosaccharides that contain a relatively hydrophobic central cavity and a hydrophilic outer surface. They are widely used to form non-covalent inclusion complexes with many substances. Although such inclusion complexes typically exhibit higher aqueous solubility and chemical stability than pure drugs, it has been shown ...
Aiassa V, Garnero C, Zoppi A, Longhi MR.
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Drug Stability: ICH versus Accelerated Predictive Stability Studies [PDF]
Pharmaceutics, 2022 The International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH), along with the World Health Organization (WHO), has provided a set of guidelines (ICH Q1A-E, Q3A-B, Q5C, Q6A-B) intended to unify the standards
Olga González-González +6 more
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A Robust Liquid Chromatographic Method for Confirmation of Drug Stability of Azithromycin in Bulk Samples, Tablets and Suspensions [PDF]
Pharmaceutics, 2017 A simple, isocratic and robust RP-HPLC method for the analysis of azithromycin was developed, validated and applied for the analysis of bulk samples, tablets and suspensions.
Alex O. Okaru +4 more
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Stability of antimycobacterial drugs in susceptibility testing [PDF]
Antimicrobial Agents and Chemotherapy, 1992 Aqueous solutions of 0.02% isoniazid, 0.2% streptomycin, 0.2% para-aminosalicylate, and 0.5% ethambutol and ethylene glycol solutions of 0.5% ethionamide stored at 3 to 7 degrees C remained stable for 1 year, as did aqueous solutions of 0.05% ethionamide hydrochloride, 0.05% kanamycin, 0.05% viomycin, and 0.1% capreomycin stored at -20 degrees C.
M E Griffith, H L Bodily
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Biopolymeric Nanogel as a Drug Delivery System for Doxorubicin—Improved Drug Stability and Enhanced Antineoplastic Activity in Skin Cancer Cells [PDF]
PharmaceuticalsIn this study, doxorubicin was loaded in a chitosan–albumin nanogel with the aim of improving its stability and exploring the potential of the system in the treatment of skin cancer. Infrared spectroscopy and X-ray diffraction confirmed the encapsulation
Lyubomira Radeva +6 more
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The Value of Drug Stability Studies and Their Publication. [PDF]
Can J Hosp Pharm, 2018 -
Brown G.
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Compressed Oxygen in Drug Stability Experiments
Chemical and Pharmaceutical Bulletin, 2007 A drug stability experiment accelerated by compressed oxygen was established. The stability of 10% ascorbic acid solution as a model was studied and the kinetic parameters were obtained with the newly established experimental method. Because ascorbic acid degrades under both anaerobic and aerobic conditions, the total rate constant k(total) can be ...
Lin-Li Li +6 more
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Stability of furosemide and torasemide in parenteral nutrition admixture [PDF]
Acta Poloniae Pharmaceutica, 2023 Furosemide and torasemide (loop diuretics) are used to treat hypertension or pulmonary edema. They are often administered in the parenteral route. In critically ill patients, there is a problem of a limited number of venous accesses, which complicates ...
Szymon Tomczak +2 more
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Stability Tests and Analytical Methods of Tacrolimus: A Review [PDF]
ImmunoAnalysis, 2022 Tacrolimus is an immunosuppressive drug widely used in organ or tissue transplantation. Furthermore, its anti-inflammatory effects are employed in treatments for psoriasis, uveitis, and vernal keratoconjunctivitis.
Sara Sajjadi +2 more
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