Results 1 to 10 of about 248,997 (274)

Residual Channel Attention Network for Brain Glioma Segmentation [PDF]

open access: yes2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 2022
A glioma is a malignant brain tumor that seriously affects cognitive functions and lowers patients' life quality. Segmentation of brain glioma is challenging because of interclass ambiguities in tumor regions. Recently, deep learning approaches have achieved outstanding performance in the automatic segmentation of brain glioma.
arxiv   +1 more source

ZDHHC15 promotes glioma malignancy and acts as a novel prognostic biomarker for patients with glioma

open access: yesBMC Cancer, 2023
Background Glioma is the most common and aggressive tumor in the adult brain. Recent studies have indicated that Zinc finger DHHC-type palmitoyltransferases (ZDHHCs) play vital roles in regulating the progression of glioma.
Zhen-Yuan Liu   +8 more
doaj   +1 more source

PTPRZ1-MET FUsion GENe (ZM-FUGEN) trial: study protocol for a multicentric, randomized, open-label phase II/III trial

open access: yesChinese Neurosurgical Journal, 2023
Background PTPRZ1-MET fusion was reported to associate with glioma progression from low-grade to high-grade glioma, which was a target by a MET inhibitor vebreltinib.
Zhaoshi Bao   +7 more
doaj   +1 more source

Clinical and Biological Significances of a Methyltransferase-Related Signature in Diffuse Glioma

open access: yesFrontiers in Oncology, 2020
Methylation of DNA, RNA or protein is a reversible modification. The proteins and genes that regulate this modification can be a candidate target for tumor therapy. However, the characteristics of methyltransferase related genes in glioma remain obscure.
Ying Zhang   +11 more
doaj   +1 more source

TERT mutations-associated alterations in clinical characteristics, immune environment and therapy response in glioblastomas

open access: yesDiscover Oncology, 2023
Objective TERT is the most frequently mutated gene in adult glioblastomas (GBMs) defined by the 2021 World Health Organization classification system. The present study aims to explore differences in clinical characteristics and immune microenvironment ...
Feng Tang   +6 more
doaj   +1 more source

Characterization of tumor-associated reactive astrocytes in gliomas by single-cell and bulk tumor sequencing

open access: yesFrontiers in Neurology, 2023
ObjectiveAstrocytes constitute approximately 30% of cells in gliomas and play important roles in synapse construction and survival. Recently, JAK/STAT pathway activation associated with a new type of astrocyte was reported.
Chuan-bao Zhang   +9 more
doaj   +1 more source

SAMD9 Is Relating With M2 Macrophage and Remarkable Malignancy Characters in Low-Grade Glioma

open access: yesFrontiers in Immunology, 2021
Immunoreactions regulated by TAMs (Tumor-associated macrophages) play a pivotal role in tumorigenesis and metastasis. In recent decades, treatments based on immune regulation have achieved revolutionary breakthroughs in cancer targeted therapies.
Wenping Ma   +14 more
doaj   +1 more source

The University of California San Francisco Preoperative Diffuse Glioma MRI (UCSF-PDGM) Dataset [PDF]

open access: yesRadiology: Artificial Intelligence 4.6 (2022): e220058, 2021
Here we present the University of California San Francisco Preoperative Diffuse Glioma MRI (UCSF-PDGM) dataset. The UCSF-PDGM dataset includes 500 subjects with histopathologically-proven diffuse gliomas who were imaged with a standardized 3 Tesla preoperative brain tumor MRI protocol featuring predominantly 3D imaging, as well as advanced diffusion ...
arxiv   +1 more source

Weighted correlation network analysis identifies multiple susceptibility loci for low‐grade glioma

open access: yesCancer Medicine, 2023
Background The current molecular classifications cannot completely explain the polarized malignant biological behavior of low‐grade gliomas (LGGs), especially for tumor recurrence.
Xiaodong Niu   +8 more
doaj   +1 more source

Systematic Analysis of a Pyroptosis-Related Signature to Predict the Prognosis and Immune Microenvironment of Lower-Grade Glioma

open access: yesCells, 2022
Current treatments for lower-grade glioma (LGG) do not effectively improve life expectancy rates, and this is a major global health concern. Improving our knowledge of this disease will ultimately help to improve prevention, accurate prognosis, and ...
Yongze He   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy