Results 1 to 10 of about 22,728 (180)

Homocysteine Metabolism in Pregnancy and Developmental Impacts

open access: yesFrontiers in Cell and Developmental Biology, 2022
Homocysteine is a metabolite generated by methionine cycle metabolism, comprising the demethylated derivative of methionine. Homocysteine can be metabolised by the transsulphuration pathway to cystathionine, which requires vitamin B6, or can undergo ...
Stephen W. D’Souza, Jocelyn D. Glazier
doaj   +1 more source

Homocysteine levels correlate with AVSS-RigiScan test parameters in men with erectile dysfunction

open access: yesBasic and Clinical Andrology, 2023
Background Although elevated homocysteine levels have been shown to affect penile erection, the relationship between homocysteine and erection at the tip or base of the penis has not been extensively studied.
Xin Qian   +5 more
doaj   +1 more source

Ability of dietary factors to affect homocysteine levels in mice: a review

open access: yesNutrition & Metabolism, 2021
Homocysteine is associated with several diseases, and a series of dietary factors are known to modulate homocysteine levels. As mice are often used as model organisms to study the effects of dietary hyperhomocysteinemia, we collected data about ...
Christine Brütting   +3 more
doaj   +1 more source

Homocysteine inhibits hepatocyte proliferation via endoplasmic reticulum stress. [PDF]

open access: yesPLoS ONE, 2013
Homocysteine is an independent risk factor for coronary, cerebral, and peripheral vascular diseases. Recent studies have shown that levels of homocysteine are elevated in patients with impaired hepatic function, but the precise role of homocysteine in ...
Xue Yu   +4 more
doaj   +1 more source

Plasma homocysteine levels in patients with liver cirrhosis [PDF]

open access: yesVojnosanitetski Pregled, 2013
Background/Aim. Homocysteine (2-amino-4-mercaptobutyric acid) is an amino acid that may be found in small quantities in all cells, and is quantitatively the major methionine metabolite. The most prevalent form is protein-bound homocysteine (about 80%),
Ćulafić Đorđe M.   +3 more
doaj   +1 more source

Elevated plasma homocysteine upon ischemic stroke is associated with increased long-term mortality in women. [PDF]

open access: yesPLoS ONE, 2017
Ischemic stroke is a leading cause of death worldwide, despite preventive and therapeutic advances during the last twenty years. Blood-borne biomarkers have been studied in association to short- and long-term outcome, in order to investigate possible ...
Ioanna Markaki   +3 more
doaj   +1 more source

Apoptosis of bone marrow mesenchymal stem cells caused by homocysteine via activating JNK signal. [PDF]

open access: yesPLoS ONE, 2013
Bone marrow mesenchymal stem cells (BMSCs) are capable of homing to and repair damaged myocardial tissues. Apoptosis of BMSCs in response to various pathological stimuli leads to the attenuation of healing ability of BMSCs.
Benzhi Cai   +11 more
doaj   +1 more source

Role of homocysteine in the development and progression of Parkinson’s disease

open access: yesAnnals of Clinical and Translational Neurology, 2020
Homocysteine is an essential intermediate product of biochemical reactions that is present in various tissues of the human body. Homocysteine may be associated with the development and progression of Parkinson’s disease.
Xiaoyan Fan   +6 more
doaj   +1 more source

Mining literature for a comprehensive pathway analysis: A case study for retrieval of homocysteine related genes for genetic and epigenetic studies

open access: yesLipids in Health and Disease, 2006
Homocysteine is an independent risk factor for cardiovascular diseases. It is also known to be associated with a variety of complex disorders. While there are a large number of independent studies implicating homocysteine in isolated pathways, the ...
Mahajan Anubha   +6 more
doaj   +1 more source

Increased Plasma Homocysteine Levels Are Associated with Left Ventricular Hypertrophy in Hypertensive Patients with Normal Renal Function

open access: yesKidney & Blood Pressure Research, 2023
Introduction: Renal function has an important bearing on plasma homocysteine levels. Plasma homocysteine is related to left ventricular hypertrophy (LVH).
Lingyu Zhang   +5 more
doaj   +1 more source

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